Bas van Woudenberg

Methylobacterium extorquens!

Aromatic acid metabolism in Methylobacterium extorquens reveals interplay between methylotrophic and heterotrophic pathways www.biorxiv.org/content/10.1... #jcampubs

Interested in Sustainability, Metabolic Engineering and Evolution?
Check out how we convinced E. coli to grow on the CO2-derived substrate formic acid using the synthetic Serine Threonine Cycle! ♻️🌱🦠

OPEN ACCESS publication to be found here:
🚨 doi.org/10.1016/j.ym... 🚨

#MEvoSky #microsky

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Beyond the pink: uncovering the secrets of pink pigmented facultative methylotrophs - Archives of Microbiology Pink Pigmented Facultative Methylotrophs (PPFMs) belong to a diverse group of methylotrophic bacteria predominantly in the genus Methylobacterium, and are known for their beneficial interactions with ...

Beyond the pink: uncovering the secrets of pink pigmented facultative methylotrophs link.springer.com/article/10.1... #jcampubs

Upcycling of polyamides through chemical hydrolysis and engineered Pseudomonas putida - Nature Microbiology Metabolic engineering guided by laboratory evolution enables upcycling of nylon by Pseudomonas putida.

www.nature.com/articles/s41...

Design and regulation of engineered bacteria for environmental release - Nature Microbiology Chemla et al. review the release of bacteria into the environment and propose engineering strategies to help improve performance and reduce risk.

REVIEW: Design and regulation of engineered bacteria for environmental release

by Chris Voigt & co

#microsky

www.nature.com/articles/s41...

Methanol transfer supports metabolic syntrophy between bacteria and archaea - Nature Zhaonella formicivorans produces methanol, for a novel syntrophic interaction, without requiring methylated compounds as an input.

Methanol transfer supports metabolic syntrophy between bacteria and archaea www.nature.com/articles/s41... #jcampubs

Designing strong inducible synthetic promoters in yeasts - Nature Communications Inducible promoters that control gene expression in response to small molecules are essential in synthetic biology. Here, the authors describe a simple and reliable approach for constructing strongly…

Eukaryotic promoters are complex, making synthetic promoter design challenging. In a recent paper, Masahiro Tominaga’s team decoded key design rules and demonstrated the potential of their inducible yeast promoters for biologic production. Learn more 👇

Led astray by 16S rRNA: phylogenomics reaffirms the monophyly of Methylobacterium and lack of support for Methylorubrum as a genus academic.oup.com/ismej/advanc... #jcampubs

Monitoring and dynamically controlling glucose uptake rate and central metabolism - Nature Chemical Engineering Glucose uptake is the initial step in cellular metabolism, and its uptake rate directly determines the overall metabolic flow. Here the authors develop a set of programmable bifunctional biosensors fo...

🚨 Out now with free access!

A set of programmable bifunctional biosensors for real-time monitoring of glucose uptake rates and dynamic dual control of glucose uptake and central metabolism. #ChemSky #ChemBio

Link: www.nature.com/articles/s44...

Measurements of translation initiation from all 64 codons in E. coli Abstract. Our understanding of translation underpins our capacity to engineer living systems. The canonical start codon (AUG) and a few near-cognates (GUG,

Some examples showing this from my group's research:
doi.org/10.1093/nar/...

doi.org/10.1101/2021...