Charlie Wilson

HAPPY HOLIDAYS TO ALL OF YOU!🎄✨

Thanks for CNRS Biologie for highlighting our new work - more to come...

Without monkeys, neuroscience has no future Research in primate brains has been essential for the development of BCIs, ANNs. New funding and policy changes put future such advances at risk.

Research in primate brains has been essential for the development of brain-computer interfaces and artificial neural networks. New funding and policy changes put future such advances at risk, write Cory Miller, @movshon.bsky.social and Doris Tsao.

#neuroskyence

bit.ly/47MXYLH

Transcriptomic diversity of amygdalar subdivisions across humans and nonhuman primates Specialized cell types and links to psychiatric disorders are revealed by genetic mapping of primate amygdala neurons.

A spatially resolved transcriptomic atlas of the primate amygdala (human, macaque, and baboon) now out in Science Advances (www.science.org/doi/10.1126/...). The amygdala contains 32 types of neurons with many neuron types specific to particular subdivisions.

Lots of updates from the preprint!

A fun hippo thread that is worth your time…
“ it makes neutering them a copper-plated bitch.”

Kraftwerk gets it
#neuroscience

Why academia is sleepwalking into self-destruction. My editorial @brain1878.bsky.social If you agree with the sentiments please repost. It's important for all our sakes to stop the madness
academic.oup.com/brain/articl...

Change in Paris air quality between 2007 and 2023 using visuals

Air pollution has dropped significantly in #Paris in the last 15 years. Mayor @annehidalgo.bsky.social’s leadership has traded car space for green space, safe bike space, kid space.. and traded pollution for people.

Good trade.

Yes, sorry, got distracted earlier (literally by some French people going on strike 🇫🇷) but meant to follow-up with Baxter's paper. We have datasets on their slow way out which support their finding of no behavioural (or for us ephys) evidence of off-target effects at 0.1mg/kg DCZ sans DREADDs.

Resting-State fMRI-Based Screening of Deschloroclozapine in Rhesus Macaques Predicts Dosage-Dependent Behavioral Effects Chemogenetic techniques, such as designer receptors exclusively activated by designer drugs (DREADDs), enable transient, reversible, and minimally invasive manipulation of neural activity in vivo . Th...

We do control DCZ injections prior to vector surgery for this reason. "Off target" effects at higher doses have been shown (paper from @rudebecklab.bsky.social and @russbeneuro.bsky.social www.jneurosci.org/content/42/2...), and we have seen similar things in MRI but so far not in ephys/behaviour.

🥰

Very sad news, an inspiring scientist.

Mr White *deserves* to taste that prime rib...

It is, needless to say, magnificent.

Year of my birth, a very treasured present. I've planned it for the last glass on my 50th...

I still have a bottle of 1979 on the go... slow...

Joyeux Noël!

Open letter to Sir Patrick Vallance To sign the letter, please complete the form here: https://forms.gle/eRydV6VpMQVFPtdF7 Please forward a link to this letter to any colleagues who you think may be interested in signing – we would li...

MRC Units across the UK have led the scientific world for generations, but are due to be closed with little consultation, for reasons that are largely unknown. Please sign this letter if you would like the MRC to reconsider. docs.google.com/document/d/1...

Bravo Jimmy.

But perfect might be stretching it a bit....

Surfing beta burst waveforms to improve motor imagery-based BCI Abstract. Our understanding of motor-related, macroscale brain processes has been significantly shaped by the description of the event-related desynchronization (ERD) and synchronization (ERS) phenome...

New 💥beta burst💥 paper! With Sotirios Papadopoulos, Jérémie Mattout of @cophy.bsky.social, and @maciekszul.bsky.social, we show how waveform-specific beta burst rates outperform classic motor imagery BCI approaches based on beta power

direct.mit.edu/imag/article...

Surfing beta burst waveforms to improve motor imagery-based BCI Abstract. Our understanding of motor-related, macroscale brain processes has been significantly shaped by the description of the event-related desynchronization (ERD) and synchronization (ERS) phenome...

Check out our recent article by Sotirios Papadopoulos, Jérémie Mattout, @maciekszul.bsky.social, @danclab.bsky.social et al.!
direct.mit.edu/imag/article...

Congratulations to Sotirios and all!

But also if you're already skeeting paper threads, you didn't party hard enough last night...

One of those days where you bust out the soldering iron half way through the experiment 🤷‍♂️

Older women participating to a race at the Senior Games 2023.

⚠️ New preprint !
« Social determinants of cognitive aging trajectories across 39 countries »
Some people in their 80s have cognitive abilities similar to many 30-year-olds, others are severely diminished. 
How comes?

www.medrxiv.org/content/10.1...
A short 🧵👇 1/7

I have not seen a starter pack for the study of brain rhythms. So, here's a start.
go.bsky.app/A6zgHeE

Would appreciate being part of this if it is possible. Plenty of frontal beta work coming up… Thanks

Do you know how dark Twitter has to be for *STEPHEN KING* to say it’s too dark

I've largely been absent from the socials, for reasons, but as this place seems to have a reasonable discussion to bullshit ratio, and folks are here now, let's give it another go. Here is an introductory thread for all these lovely new followers....

He, me too. Thanks!