Sebastián Jara

As Requested - A Starter Pack of PIs in Biology (or adjacent) fields who are recruiting POSTDOCS! Please don't hesitate to reach out if you wish to be added! go.bsky.app/4gbXXR3

Professor in Neuroimmunology - DEMENTIA RESEARCHER The Salk Institute seeks a Professor in Neuroimmunology to lead innovative research on nervous and immune system interactions within a world-class setting

The Salk Institute seeks a Full Professor in Neuroimmunology to lead innovative research on nervous and immune system interactions within a collaborative, world-class setting. Closing date: 7th September

www.dementiaresearcher.nihr.ac.uk/job/professo...

Barcoded viral tracing identifies immunosuppressive astrocyte–glioma interactions - Nature Using viral barcode tracing to detect interactions between glioblastoma cells and non-malignant astrocytes in patient samples, investigators discovered a pathway that reduces tumour-specific immunity ...

Our newest paper studying immunosuppressive astrocyte-GBM interactions using RABID-seq is out in ‪@nature.com today! Congrats to Brian Andersen and Camilo Faust Akl!
www.nature.com/articles/s41...

Expansion microscopy reveals nano-scale insights into the human neuromuscular junction Ramadan et al. employ expansion microscopy to visualize neuromuscular junctions in human and mouse muscles. Their findings demonstrate expansion microscopy as an accessible and cost-effective approach...

New paper from the lab 🚨: Expansion microscopy reveals nano-scale insights into the human neuromuscular junction: Cell Reports Methods www.cell.com/cell-reports...

Calling all Neuroscience postdocs! 🧠 Share your research through SPiNES (Seminars from Postdocs in Neuroscience: Extramural Series) from the NYUGSoM Department of Neuroscience. Applications close 08/20/25. Apply today! 👉 nyumc.qualtrics.com/jfe/form/SV_...
#Neuroscience #Postdoc #ResearchOpportunity

AxoDen: An Algorithm for the Automated Quantification of Axonal Density in Defined Brain Regions The rodent brain contains 70,000,000+ neurons interconnected via complex axonal circuits with varying architectures. Neural pathologies are often associated with anatomical changes in these axonal pro...

🧠🐁

Interested in a quick / reliable / reproducible tool to quantify your fluoresently-tagged axons ?

Check out AxoDen, a no-coding-needed web app and downloadable GUI ...

Designed + developed entriely by the amazing Raquel Adaia Sandoval Ortega

www.eneuro.org/content/12/6...

Happy to share my first publication with @patrikernfors.bsky.social Lab - all about the DRG: Chromatin accessibility, single cell and spatial RNA sequencing - a great source for everyone interested in sensory neurons and non-neuronal cell of the DRG 😊

Choroid plexus apocrine secretion shapes CSF proteome during mouse brain development Nature Neuroscience - The choroid plexus (ChP) provides molecular cues for brain development. However, the underlying mechanisms are unclear. This study identifies an apocrine secretion mechanism...

Led by @scienceyael.bsky.social & out today in @natneuro.nature.com: the brain's fluid-secreting organ — the choroid plexus — can reshape neural development through a powerful, little-known process. & it can be hijacked by serotonergic drugs like LSD. 🧠👇 A thread
rdcu.be/eoaSY

Heatmap from the linked paper in figure 2, of hDRG and nerve proteomics showing the detection of TRP- and SCN- channels across samples, with higher levels of myelin-related proteins in the nerve and higher levels of TRPV1 and SCN10a in the ganglia

We set out to map a detailed proteome of the human DRG and nerve using DIA-MS as a reference to the field, and I think we've succeeded! Lots of proteins (& lots of ion channels), with the data is fully searchable. It's also available on @sparc.science

sensoryomics.shinyapps.io/Proteomics/

Our lab's 1st paper, led by @fchrisbennett.bsky.social & @waisenberg.bsky.social. A decade thinking how to directly assess the impact of microglia replacement. Yrs of hard work. This kind of work is needed to expand brain disease care for kids & the vision for safer, more effective cell therapy.

🤍🖤

Interoceptive processing in the nucleus of the solitary tract The interoceptive nervous system continuously monitors the status of visceral organs to synthesize internal perceptions and regulate behavioral and ph…

Lots of recent papers discuss the nucleus of the solitary tract in interoception. In this review, we take a sensory processing perspective on how interoceptive signals are encoded in the NTS:
www.sciencedirect.com/science/arti...

SCAM ALERT. This is a fake conference that ripped off my and other people’s names to trick people into registering. There is no such conference that I or the others shown were invited or agreed to. We are working to try to get this fraud taken down from the web.

chemsymposia.com

MicroRNA mechanisms instructing Purkinje cell specification Zolboot et al. introduce DD-T6B and SAP-seq, methods for investigating microRNA function with enhanced spatiotemporal resolution, and identify Purkinje cell-specific microRNAs and targets instructing ...

✨So happy to see part of my PhD work with @lippilab.bsky.social out today in @cp-neuron.bsky.social! ✨

We developed new tools to study microRNA-target networks with greater spatial and temporal resolution and found neuronal subtype- and developmental stage-specific roles:

A single-cell transcriptomic atlas of sensory-dependent gene expression in developing mouse visual cortex Summary: Single-cell RNA sequencing of developing mouse visual cortex uncovers cell type-specific gene programs induced by sensory experience. All cell types mounted transcriptional responses to the e...

journals.biologists.com/dev/article/...

New work from the lab characterizing sensory-dependent transcriptomes in mouse V1 across neuronal and glial cell types. Some fun nuggets in here, and all data publicly available for download and re-analysis. Happy gene hunting!

13 chair positions open @inserm.fr to lead a junior research group in France covering #neuroscience, #immunology, #bioinformatics, #bioengineering, #biotherapy, #public health pro.inserm.fr/rubriques/co... 🧪🔬

And science continues… check out our new work led by @rbrianroome.bsky.social

Hey Neuroscientists 🧠! Heading to San Diego for #SfN25 in November? Join us for an exciting all-day symposium at @scripps.edu in beautiful La Jolla, just a couple of days before the conference. It's free to attend, so register early and plan your travels accordingly! 🧪

Differential encoding of mammalian proprioception by voltage-gated sodium channels Voltage-gated sodium channels differentially encode mammalian proprioception via distinct cellular localization patterns.

Thrilled to share the most recent pub from the Griffith Lab! We show that sodium channels play unique roles in proprioceptive encoding. We also found some really cool effects on skeletal muscle, and a dev dependent role for Nav1.6 in proprioceptive spinal circuits www.science.org/doi/10.1126/...

Color blind friendly palettes for data visualizations with categories A discussion of color blind friendly palettes for labeling unique catergories in data visualization.

Having a color-blind colleague is a good reminder that we need to be more careful when designing figures for scientific publication 🧪
My lab has found this page especially useful for selecting color palettes, used in combination with different symbols: thenode.biologists.com/data-visuali...

Macrophages excite muscle spindles with glutamate to bolster locomotion - Nature A population of macrophages with exclusive molecular and functional signatures in the muscle spindles express machinery for synthesizing and releasing glutamate, and a cellular component, the muscle s...

Here is our latest discovery: macrophages that behave like neurons to help you walk
Thanks to Bellardita's lab!
www.nature.com/articles/s41...

BOOM! Re-upping our Pain Research Starter Pack since so many people have joined this glorious place in the past week. If you are not on the list and want to be added, let me know and I will add you... I have been doing my best to keep this updated.
#painresearch
go.bsky.app/KboKNhg

Axon Degeneration starter pack now updated. Plenty of room for more so give me a nudge if you’d like to be added.

I would very much like to be included! Thank you!

Thank you! I would appreciate to be included as well!

Congrats!! 🙌🙌

🙋‍♂️😁