Dr Rajiv Sankaranarayanan

🚨More #HFSA2025 sim pubs out today @Jcardfail! 🚨

Hemodynamics and crosstalk between HF & EP! 📃🫀

🚨 #HFSA2025 SimPub alert!

The Heart Failure Society America’s 2025 Annual Scientific Meeting kicks off today, and JCF has 12 simultaneous publications releasing during the meeting!

#WorldHeartDay ❇️Exciting agenda on Sep 29th @liverpoolccs.bsky.social chaired by Prof Gregory Lip @lukaszkuzma.bsky.social delivers the Key Note Lecture. @worldheart.org @pumpingmarvellous.bsky.social @evertoninthecommunity.org @thebhf.bsky.social

Prevalence of pulmonary hypertension in HF is about 50%, with some variation depending on use of echo vs. RHC and HFpEF vs HFrEF. Unfortunately, the I2 heterogeneity is almost 100% onlinelibrary.wiley.com/doi/epdf/10.... #cardiosky

🫀 When heart failure meets CV prev, saving hearts is our focus.

@aspcardio.bsky.social & @hfsa.bsky.social Joint Scientific Statement, The Continuum of Prevention & Heart Failure in Cardiovascular Medicine, calls for a prevention-first approach at every stage.

www.sciencedirect.com/science/arti...

Comparative performance of risk prediction indices for mortality or readmission following heart failure hospitalization Comparative performance of 7 risk prediction indices in patients hospitalized for heart failure. In this cohort of 1206 patients, the LENT index offered the greatest discrimination, calibration, and ...

The simple LENT index—using length of stay, prior ED visits, and NT-proBNP—best predicts 30-day death or readmission after #HeartFailure hospitalization. Accurate, easy, and practical! #RiskPrediction @drrajivsankar.bsky.social @mmamas1973.bsky.social onlinelibrary.wiley.com/doi/10.1002/...

#Aldosterone-targeted therapies: early implementation in resistant #HTN and #CKD

Reflecting on the fundamentals and exploring future directions

academic.oup.com/eurheartj/ad...
#CardioSky @escardio.bsky.social #EHJ @cardioobdoc.bsky.social @shelleyzieroth.bsky.social @drrajivsankar.bsky.social

Finerenone, glycaemic status, and heart failure with mildly reduced or preserved ejection fraction: A prespecified analysis of the FINEARTS‐HF trial Finerenone and glycaemic status in patients with heart failure with mildly reduced/preserved ejection fraction. CI, confidence interval; CV, cardiovascular; HF, heart failure; HR, hazard ratio; RR, r...

#Finerenone reduced the risk of CV death and total worsening HF events, and was well-tolerated, independent of glycaemic status in HFmrEF/HFpEF

@escardio.bsky.social @shelleyzieroth.bsky.social @drrajivsankar.bsky.social @docbhardwaj.bsky.social

onlinelibrary.wiley.com/doi/full/10....

Conduction system pacing: promoting the physiology to prevent HF

Background and Clinical perspectives of HBP and LBBP area in HF
link.springer.com/article/10.1...

#HF #CardioSky #CardioEd @cardioobdoc.bsky.social @drrajivsankar.bsky.social @annakatebarton.bsky.social @vietheartpa.bsky.social

Multicentre comparison of various microaxial pump devices as a bridge to durable assist device implantation

onlinelibrary.wiley.com/doi/10.1002/... #Impella #CardioSky #CardiogenicShock #LVADs
@drrajivsankar.bsky.social @shelleyzieroth.bsky.social @cardioobdoc.bsky.social @hvanspall.bsky.social

Lower extremity lymphatic flow is associated with diuretic response in acute heart failure

In 65 AHF patients, lymphatic flow (via ICG lymphangiography) predicted diuretic response.

#AHF #CardioSky #Lymphatics #AHF @shelleyzieroth.bsky.social @escardio.bsky.social @drrajivsankar.bsky.social

Lower extremity lymphatic flow is associated with diuretic response in acute heart failure Lower extremity lymphatic flow and diuretic response in acute heart failure (AHF). IV, intravenous. (Created in BioRender)

Faster lower limb lymph flow was linked with better diuretic efficacy in AHF.

#CardioSky @escardio.bsky.social #EJHF @cardioobdoc.bsky.social @noshreza.bsky.social @novitham.bsky.social @drrajivsankar.bsky.social @vietheartpa.bsky.social

onlinelibrary.wiley.com/doi/10.1002/...

The dream team! So desperately hoping every one of you will be voted in by colleagues 💙

Please encourage your FRCP colleagues to vote before Monday 14th April

Vote Asif Qasim for President

@drlkvaughan.bsky.social for VP
@respirologist.bsky.social Dr Philip Pearson for Council
@copddoc.bsky.social Prof Nick Hopkinson for Council

#TimeForChange

#VoteAsifQasim #TimeForChange

PRCP Election — Dr Asif Qasim, MA PhD FRCP Dr Asif Qasim candidate for election at President of the Royal College of Physicians - restoring the RCP as the Voice of Physicians

Thank you for your votes & support in the RCP Election - your endorsements to #VoteAsifQasim send a powerful message.

We need a fresh start, with new leadership #TimeForChange.

I am committed to rebuilding pride in the RCP & restoring your #VoiceOfPhysicians

#VoteAsifQasim

asifqasim.co.uk/prcp

More from Dr. Masri from Day 2 at #ACC.25...

Adding #Whycmr to the mix of risk in patients with #ATTR #cardiomyopathy. @accintouch.bsky.social #CardioSky #Cardiology #MedSky #ACC25

Evolut Low Risk: Pts w/ severe #vhdAS who were treated w/ either #TAVR/surgery had comparable rates of all-cause mortality or disabling #stroke at 5️⃣ years. Valve durability & performance were also excellent in both groups. #ACC25

🔗 bit.ly/43wW1m7 #JACC @jaccjournals.bsky.social

#CardioSky #MedSky

FLAVOUR-II: Novel #AI-Powered Imaging Technique Noninferior to IVUS in #PCI

Read the journal scan to learn more: bit.ly/4j8u8oP #ACC25

#CardioSky #MedSky

Roxana Mehran shares the breakthroughs from PROTECT-TAVI

#ESCTVOnTheRoad #ACC25

#ACC25 #cardiosky #EVOLUT

📎https://www.jacc.org/doi/10.1016/j.jacc.2025.03.004?utm_medium=print_qr&utm_source=author&utm_campaign=spub&utm_content=author

#ACC25 #LBCT 5 year #EVOLUT Trial
❤️Low risk patients with symptomatic AS: what are the 5y outcomes of Sx 🆚 TAVI
💔1/3 Female
💔 all-cause Mortality gap ⬇️ with time
💔 CV mortality ⬇️ for TAVI
💔more pacemaker with EVOLUT

💥EVOLUT IN LOW RISK PATIENTS SAFE ALTERNATIVE TO Sx

MIGHTy-Heart: A program that delivered in-home visits from a trained paramedic team to people with #HeartFailure did not significantly reduce 30-day 🏥 readmissions or improve health status compared with standard follow-up 📞 calls. #ACC25

Learn more: bit.ly/41SPhOe

#CardioSky #MedSky

In an individual patient data meta-analysis of 7,805 patients enrolled in 7 RCTs, Dr. @rohankhera.bsky.social and colleagues of @cardslab.bsky.social found evidence of superiority for tirzepatide in resolving metabolic syndrome www.jacc.org/doi/10.1016/...

#ACC25 #JACC #T2D #diabetes

Dr. Amy Sarma:
Who needs monogenic genetic testing for #SCAD ?
✅Men
✅Aortic aneurysm
✅Family history
✅SCAD pt wanting pregnancy

Otherwise likely polygenic
@accintouch.bsky.social #acc25
#cvprev

Dapagliflozin in Patients Undergoing Transcatheter Aortic-Valve Implantation | NEJM Sodium–glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of heart-failure admission among high-risk patients. However, most patients with valvular heart disease, including those undergoing...

At the #ACC25

Flozinate (after TAVI) www.nejm.org/doi/full/10....

Glipinate (oral) www.nejm.org/doi/full/10....

Update on preclinical models of cancer therapy-related cardiac dysfunction: Challenges and perspectives
A scientific statement of the #HFA of @escardio.bsky.social

onlinelibrary.wiley.com/doi/full/10.... @shelleyzieroth.bsky.social @cardioobdoc.bsky.social @drrajivsankar.bsky.social #CardioSky

Reappraisal of #RCTs cited in North American & EU dyslipidemia guidelines:

📍 Many meeting RCT eligibility criteria had low 10-yr risk per risk scores & wouldn’t qualify for statins.

📍 Trials with lower LDL-C enrollees had older patients + more risk factors.
academic.oup.com/eurjpc/advan...

Risk Factors for Post−COVID-19 Condition This systematic review and meta-analysis evaluates the findings of 41 studies with a total of 860 783 patients to identify risk factors associated with post−COVID-19 condition.

Worth a reminder 👆 (& a repost!)

jamanetwork.com/journals/jam...

@drmarthagulati.bsky.social @gbiondizoccai.bsky.social @hancardiomd.bsky.social @anastasiasmihaili.bsky.social @annakatebarton.bsky.social @cardioobdoc.bsky.social @benoyshah.bsky.social @drrajivsankar.bsky.social

I am running for Clinical VP of the RCP.

For those who don't know me, here is a potted bio.
🧵