Stefan Ruhl 🦷💧🦠

academic.oup.com/gbe/article/...
🦷🦷 #TEETH 🥛🥛 #MILK 💧💧 #SALIVA❗️

The answer is yes. We expect to learn about the functions of saliva in humans through comparative investigations with other mammalian species, most importantly other primates.

SCPP gene presence/absence phylogeny. Blocks represent genes within the SCPP locus, color-coded by functional relevance: enamel (purple), milk (blue), saliva (yellow), and genes implicated in all three functions (red). The animal phylogeny is shown on the left with species silhouettes. Two primate species (baboon and green monkey) are depicted placing blocks representing saliva-related genes at the points in evolution where these genes emerged. Imagine designed in BioRender.

Pajic, @gokcumenlab.bsky.social @spit-lab.bsky.social et al. explored the evolution of saliva-related SCPP genes, observing extensive diversification of SCPP genes within mammals, driven by gene duplications and losses.

🔗 doi.org/10.1093/gbe/evaf165

#genome #evolution #primates

Saliva Protein Genes in Humans were Shaped During Primate Evolution Abstract. Genes within the secretory calcium-binding phosphoprotein locus diversified along with the formation of a calcified skeleton in vertebrates, the

What have 🦷🦷 #TEETH 🦷🦷, 🥛 #MILK 🥛, and💧💧 #SALIVA 💧💧to do with each other? Ask PetarPajic, Luane Landau, and Omer Gokcumen @gokcumenlab.bsky.social ❗️

academic.oup.com/gbe/article-...

🦷🦷 #TEETH ❗️🦷🦷

🦷🦷 #TEETH❗️🦷🦷

Ghost sharks grow forehead teeth to help them have sex Male “ghost sharks” — eerie deep-sea fish known as chimaeras that are related to sharks and rays — have a strange rod jutting from their foreheads, studded with sharp, retracta...

🦷🦷 #TEETH ❗️🦷🦷
Ghost sharks grow forehead teeth to help them have sex | EurekAlert! www.eurekalert.org/news-release...

Behold the Gloriously Weird Spotted Ratfish. It Has Teeth on Its Forehead for Sex Researchers have finally traced the origin of the spotted ratfish’s bizarre forehead teeth, which are used for mating

🦷🦷 #TEETH ❗️🦷🦷
www.scientificamerican.com/article/this...

🦷🦷 #TEETH ❗️🦷🦷

The gene from Denisovan to Neanderthal to modern mucus A “genetic sandwich” reveals how a block of DNA entered several populations successively and was affected by natural selection.

Thank you for the write-up @johnhawks.net in particular for dedicating space to explaining mucin structure and function.

The gene from Denisovan to Neanderthal to modern mucus
open.substack.com/pub/johnhawk...

The MUC19 gene: An evolutionary history of recurrent introgression and natural selection We study the gene MUC19, for which some modern humans carry a Denisovan-like haplotype. MUC19 is a mucin, a glycoprotein that forms gels with various biological functions. We find diagnostic variants ...

Our paper on the evolution of MUC19 in humans, Neanderthals, and Denisovans is finally out today in Science!

This has been a six-year effort by 13 authors to weave together 3 separate but related evolutionary stories around this one gene (more on thread 🧵).

www.science.org/doi/10.1126/...

🦷🦷 #TEETH ❗️🦷🦷

🦷🦷 #TEETH ❗️🦷🦷

Convergent evolution through independent rearrangements in the primate amylase locus Structurally complex regions of the genome are increasingly recognized as engines of evolutionary convergence due to their propensity to generate recurrent gene duplications that give rise to similar ...

Our latest preprint explores the evolution of the primate amylase locus, uncovering structural innovations, regulatory shifts and molecular convergence.
www.biorxiv.org/content/10.1...

UB oral biologists recognized on global stage Patricia Diaz, Hyuk-Jae “Edward” Kwon and Frank Scannapieco have received "distinguished scientist" awards from the IADR.

www.buffalo.edu/ubnow/storie... ⭐️⭐️⭐️

Sialic Acid Identity Modulates Host Tropism of Sialoglycan-binding Viridans Group Streptococci Microbial interactions with multiple species may expand the range of potential hosts, supporting both pathogen reservoirs and zoonotic spillover. Viri…

Congratulations, KeAndreya!
#glycotime
@keandreyam.bsky.social
share.google/G6jTNj5kL856...

Assistant Professor/Associate Professor, Oral Biology The University at Buffalo School of Dental Medicine (SDM) invites applications from qualified early- to mid-career oral health scientists and/or clinician-scientists for a full-time tenure track acade...

❗️❗️❗️👄👄 #MOUTH 👄👄 🦷🦷 #TEETH 🦷🦷 💧💧 #SALIVA 💧💧🦠🦠 #MICROBIOME🦠🦠 🍭🍭 #glycotime 🍭🍭 ❗️❗️❗️

❗️We are hiring❗️Check out this full-time tenure track academic faculty position in the #UBSDM's Department of Oral Biology.

ms.spr.ly/6045sKrT9

🎉 Today marks the 120th anniversary of the Niagara Movement, founded in Buffalo & Fort Erie in 1905 by W.E.B. Du Bois & other national black leaders. A precursor to NAACP, the group paved the way for the 20th century civil rights movement.

Learn more: discoverniagara.org/the-niagara-movement

Eighteen million years of diverse enamel proteomes from the East African Rift - Nature The isolation of dental proteins from fossils deposited 1.5 million to 18 million years ago in the Turkana Basin in Kenya, a tropical region, demonstrate the promise of dental enamel for palaeoproteom...

🦷🦷 #TEETH ❗️🦷🦷

www.nature.com/articles/s41...

🦷🦷 #TEETH❕🦷🦷

Oral Biology - Yes, that’s us!
lnkd.in/enttGneU
Now hiring:
www.ubjobs.buffalo.edu/postings/57652

#AADOCR Advocacy Day on Capitol Hill to emphasize the importance of research and education in the dental, oral, and craniofacial sciences.
🦷🦷 #FundOralHealth 🦷🦷

🦷🦷 #TEETH ‼️ 🦷🦷

🦷🦷 #TEETH ‼️ 🦷🦷

A look at the fossil skull from Steinheim The skull provides some of the best evidence for the ancestral population of Neandertals, and had a tumultuous history in the decades after its discovery.

The story of a fascinating ancient skull and the scientist who resorted to hiding it in his bedroom to keep it from being studied by Nazi anthropologists

johnhawks.net/weblog/a-loo...

Check out our new research in NPJ Biofilms and Microbiomes on the surprising patterns of oral streptococci variation in humans and the clues they encode for understanding human evolution and the recent impacts of oral hygiene. A big congratulations to Irina Velsko! www.nature.com/articles/s41...

Irawati Karve: India's trailblazing female anthropologist who challenged Nazi race theories Irawati Karve, India's first female anthropologist, led a fascinating life that challenged patriarchal norms.

www.bbc.com/news/article...