@genesdev.bsky.social
G&D publishes high-quality research in molecular biology, cancer biology, development, neuroscience and related fields. In addition, G&D also publishes comprehensive Review Articles, Perspectives and Outlooks written by leading scientists.
RESOURCE/METHODOLOGY: A genome-wide, CRISPR-based screen reveals new requirements for translation initiation and ubiquitination in driving adipogenic fate change
By Turn et al. and Peter Jackson
Learn more here:
β‘οΈ https://genesdev.cshlp.org/content/39/19-20/1241.abstract
RESEARCH PAPER: A noncanonical Pol III-dependent, Microprocessor-independent biogenesis pathway generates a germline-enriched miRNA family
By Sakhawala et al. and Katherine McJunkin
Learn more here:
β‘οΈ https://genesdev.cshlp.org/content/39/19-20/1198.abstract
RESEARCH PAPER: SUMO2 promotes histone pre-mRNA processing by stabilizing histone locus body interactions and facilitating U7 snRNP assembly
By He et al. and Michael Matunis
Learn more here:
β‘οΈ https://genesdev.cshlp.org/content/39/19-20/1182.abstract
RESEARCH PAPER: Condensation of human OAS proteins initiates diverse antiviral activities in response to West Nile virus
By Briggs et al. and James Burke
Learn more here:
β‘οΈ https://genesdev.cshlp.org/content/39/19-20/1162.abstract
RESEARCH COMMUNICATION: Structural basis of nucleosome recognition by the conserved Dsup and HMGN nucleosome-binding motif
By Alegrio-Louro et al. and Andres Leschziner
Learn more here:
β‘οΈ https://genesdev.cshlp.org/content/39/19-20/1155.full
REVIEW: Modeling and targeting general and chromosome-specific aneuploidy in cancer.
By Aleah Goldberg, Maria Trifas and Teresa Davoli
Learn more here:
β‘οΈ https://genesdev.cshlp.org/content/39/19-20/1132.abstract
π½οΈ G&D Tapes π½οΈ
G&D Author, Aishwarya Pawar, tells us about their new study showing that PHF6 and PHIP function together to suppress stemness programs and leukemia progression.
@aishwarya2510.bsky.social
@paralkarlab.bsky.social
Learn more here:
β‘οΈ genesdev.cshlp.org/content/39/1...
OUTLOOK: A new link in the leukemia genetic puzzle
By Xiaodi Wu and Ross Levine
Learn more here:
β‘οΈ https://genesdev.cshlp.org/content/39/19-20/1129.full
G&D's Editor-in-Chief, Andrew Dillin, will be at #FusionAging25
If youβd like to chat about publishing your work with #genesdev, feel free to reach out to dillin[at]berkeley[dot]edu
RESEARCH PAPER: Leukemia mutated proteins PHF6 and PHIP form a chromatin complex that represses acute myeloid leukemia stemness
By Pawar et al. and Vikram Paralkar
Aishwarya Pawar
Vikram Paralkar
Learn more here:
Β β‘οΈ https://genesdev.cshlp.org/content/39/19-20/1219.abstract
π¨ NEW ISSUE ALERT!!! π¨
New Outlook, Review and Research Papers online now at Genes & Development.
Click on the link to learn more:
β‘οΈ https://genesdev.cshlp.org/content/39/19-20.toc
How does the brain connect with each muscle to control the body? Check out new videos from @columbiamed.bsky.social & @zuckermanbrain.bsky.social that reveal two key molecules behind this vital process in fruit flies. @genesdev.bsky.social
zuckermaninstitute.columbia.edu/microscopic-...
π§ πͺπͺ°
Our study on the biogenesis of neuronal circular RNAs is out in Genes&Development @genesdev.bsky.social !
genesdev.cshlp.org/content/earl...
Our celebration picture features first authors @carlosalfonsog.bsky.social and @shimengjin.bsky.social holding the fabulous circular cake, and most co-authors.
G&D will be at Biology of Cancer 2025 #cshlcancer this week. Come find us in Grace Lobby or schedule an appointment below if you'd like to chat about your work or learn more about publishing with us.
@cshlmeetings.bsky.social @genesdev.bsky.social
β‘οΈ https://tinyurl.com/GenesDev-MeetTheEditors
RESEARCH PAPER: Bystander activation across a TAD boundary supports a cohesin-dependent transcription cluster model for enhancer function
By Williamson et al.
β‘οΈ https://tinyurl.com/gd352648
#chromatin #enhancer #transcription #sonichedgehog #TAD #cohesin #genomics #3Dgenome #loopextrusion
OUTLOOK: Lineage rewiring in lung adenocarcinoma via HNF4Ξ± and NKX2-1 dynamics
By Alice Feng, Alena Yermalovich, and Matthew Meyerson
β‘οΈ https://tinyurl.com/gd353142
Read the paper:
β‘οΈ https://tinyurl.com/gd352742
#KRAS #hybrididentity #lineage #plasticity #lungcancer #cancertherapy
G&D's Editor-in-Chief, Andrew Dillin will be at the 2025 Frontiers in Metabolism β Mechanisms of Metabolic Disease meeting at the Morgridge Institute for Research @uwmadison.bsky.social. If youβd like to chat about publishing your work with us, feel free to reach out to dillin@berkeley.edu
12.09.2025 15:49 β π 5 π 3 π¬ 1 π 0
RESEARCH PAPER: Opposing lineage specifiers induce a pro-tumor hybrid identity state in lung adenocarcinoma
By Fort et al.
β‘οΈ https://tinyurl.com/gd352742
#cancer #gastrointestinal #lung #transcriptionfactor #tumorigenesis #RAS/MEK #signaling #lineage #plasticity #cancertherapy
OUTLOOK: Speed of life: tuning the ticktock of the segmentation clock
By Sally Lowell
β‘οΈ https://tinyurl.com/gd353096
Read the paper:
β‘οΈ https://tinyurl.com/gd352909
#Notch #E3ligase #segmentationclock #somitogenesis #somitoid
RESEARCH PAPER: ELAV mediates circular RNA biogenesis in neurons
By Alfonso-Gonzalez et al.
β‘οΈ https://tinyurl.com/gd352670
#circRNA #neuroscience #RNAbindingprotein #Drosophila #embryos #neurons #mRNA #introns #splicing
REVIEW: Timing is everything: transcription bursting in development
By Jee Min Kim and Daniel Larson
β‘οΈ https://tinyurl.com/gd352465
#transcription #molecularbiology #transcriptionbursting #embryonicdevelopment #stemcell #differentiation #mRNA #development #molecularmechanism
π½οΈ G&D Tapes π½οΈ
G&D Author, Edel McCrea tells us about their new study in #genesdev reporting a role for tyrosine phosphatase PTNP14 in the sexually dimorphic regulation of Hippo pathway function.
Learn more here:
β‘οΈ https://tinyurl.com/gd352620
RESEARCH PAPER: Analysis of knockout mice reveals critical female-specific roles for the Hippo pathway component PTPN14
By McCrea et al.
β‘οΈ https://tinyurl.com/gd352620
#Hippo #Development #SexDifferences #YAPTAZ #signaling #WoundHealing #PTPN14 #CornealDisease #uterus #WomensHealth
Excited to share that our manuscript βMEF2C controls segment-specific gene regulatory networks that direct heart tube morphogenesisβ is now online @genesdev.bsky.social !
genesdev.cshlp.org/content/earl...
(1/n)
π½οΈ G&D Tapes π½οΈ
G&D Author, Hedda Meijer tells us about their recent study in #genesdev that demonstrates the functional significance of the interaction between NOTCH1/NICD and the F-box protein FBXW7 during somitogenesis.
Learn more here:
β‘οΈ https://tinyurl.com/gd352909
RESEARCH PAPER: NOTCH1 S2513 is critical for the regulation of NICD levels impacting the segmentation clock in hiPSC-derived PSM cells and somitoids
By Meijer et. al
β‘οΈ https://tinyurl.com/gd352909
#segmentationclock #NOTCH #NICD #somite #somitoid #embryo #patterning
π¨ NEW ISSUE ALERT!!! π¨
New Outlooks, Review and Research Papers online now at Genes & Development.
Click on the link for more:
β‘οΈ genesdev.cshlp.org/content/39/1...
REVIEW: Studying ovarian aging and its health impacts: modern tools and approaches
By BΓ©rΓ©nice A. Benayoun, Alison Kochersberger, and Jennifer L. Garrison
β‘οΈ genesdev.cshlp.org/content/39/1...
@bbparis1984.bsky.social @jennifergarrison.bsky.social
#reproductiveaging #ovary #aging #womenshealth
SYMPOSIUM OUTLOOK: C. elegans cognitive decline with age: more than just wiggling forward and backward
By Coleen T. Murphy
β‘οΈ genesdev.cshlp.org/content/39/1...
#animalmodels #elegans #behavior #cognition #memory #aging #cognitiveaging
SYMPOSIUM OUTLOOK: The interplay between senescence, inflammation, and the immune system
By JesΓΊs Gil
β‘οΈ genesdev.cshlp.org/content/39/1...
#senescence #aging #immune #SASP #nucleicacid #inflammation #therapy #openaccess
