Adrian Aldcroft's Avatar

Adrian Aldcroft

@ajaldcroft.bsky.social

Editor in Chief of BMJ Open.

357 Followers  |  522 Following  |  44 Posts  |  Joined: 20.11.2024  |  2.0768

Latest posts by ajaldcroft.bsky.social on Bluesky

Procalcitonin to guide antibiotic use during the first wave of COVID-19 in English and Welsh hospitals: integration and triangulation of findings from quantitative and qualitative sources Aim To integrate the quantitative and qualitative data collected as part of the PEACH (Procalcitonin: Evaluation of Antibiotic use in COVID-19 Hospitalised patients) study, which evaluated whether pro...

πŸ‘ PEACH has landed!

The final publication from the PEACH study is now live in BMJ Openβ€”marking the 8th major output from this impactful research.

πŸ”— bmjopen.bmj.com/content/15/8...

@researchwales.bsky.social
@ukcrc-ctu.org.uk πŸ“„πŸŽ―

08.08.2025 12:38 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

I'm so glad Leonard is finally receiving the recognition he deserves! Hopefully this helps relieve him of his weighty thoughts. πŸ˜‚

21.07.2025 08:34 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

He is indeed just sitting in front of his portrait contemplating his existence (also hoping I give him a treat) πŸ˜€

21.07.2025 06:59 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Preview
Dealing with continuous variables and modelling non-linear associations in healthcare data: practical guide Proper handling of continuous variables is crucial in healthcare research, for example, within regression modelling for descriptive, explanatory, or predictive purposes. However, inadequate methods ar...

Very useful, clearly presented paper published in @bmj.com about dealing with continuous variables. Handy resource for authors and editors www.bmj.com/content/390/...

17.07.2025 10:09 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Wonderful to see this article in BMJ Open having such an impact @sineadmcd89.bsky.social bmjopen.bmj.com/content/15/6...

14.07.2025 10:03 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Do patients’ and doctors’ perceptions about cardiovascular outcomes coincide?

Answer: No

Highlights the importance of patient involvement in designing research, including identifying key outcomes.

bmjopen.bmj.com/content/15/7...

14.07.2025 09:47 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

T0a: #NephJC

CKD in T2D isn’t just common - it’s deadly πŸ’£
Up to 1 in 3 people with T2D have CKD, and the risks go way beyond declining eGFR

πŸ“ˆThose with CKD had 2–3x higher rates of CV events, hospitalizations, and death

pubmed.ncbi.nlm.nih....

09.07.2025 01:09 β€” πŸ‘ 9    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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Congratulations to UBL on a πŸ†• #publication in @bmj.com Open πŸŽ‰

#Research on youth #smoking in #BiHπŸ‡§πŸ‡¦ finds:
-⬆️#cigarette prices 10% would ⬇️ likelihood of youth smoking initiation 5️⃣%, while
-parental & peer smoking would ⬆️ increase likelihood of initiation.

Learn moreπŸ‘‡
bmjopen.bmj.com/content/15/6...

09.07.2025 14:47 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Congrats to A/Prof Eric Hau, Dr Sagun Parakh & the CHEST-RT researchers on their new protocol paper in BMJ Open. The study is investigating combining thoracic #RT with chemotherapy & immunotherapy for patients with extensive-stage small-cell lung cancer.
bmjopen.bmj.com/content/15/7...

10.07.2025 04:07 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Paper published: Predicting Opportunities for Improvement in Trauma Care using Machine Learning: A retrospective registry-based study at a major trauma centre #MedSky bmjopen.bmj.com/content/15/6...

11.07.2025 08:09 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Appropriateness of NHS 111 Wales outcomesβ€”using the Call Prioritisation Streaming System: a RAND/UCLA modified Delphi method

CPSS effectively prioritises and streams patients to appropriate outcomes based on expert clinician consensus.

bmjopen.bmj.com/content/15/7...

11.07.2025 14:28 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Schematic illustration of the ecological momentary music intervention (EMMI-T). Upon reporting a stressful and/or discriminatory event (E1: β€˜pre’), participants will be randomly assigned (50:50) to listen to their study playlist (i.e., intervention event) or not (i.e., control event) (= intervention period). If assigned to an intervention event, participants may choose a music listening duration of 10 or 20 min. A post assessment (E2: β€˜post’) will be included to capture effects on subjective stress levels and biological stress markers (salivary cortisol, salivary alpha-amylase).

Schematic illustration of the ecological momentary music intervention (EMMI-T). Upon reporting a stressful and/or discriminatory event (E1: β€˜pre’), participants will be randomly assigned (50:50) to listen to their study playlist (i.e., intervention event) or not (i.e., control event) (= intervention period). If assigned to an intervention event, participants may choose a music listening duration of 10 or 20 min. A post assessment (E2: β€˜post’) will be included to capture effects on subjective stress levels and biological stress markers (salivary cortisol, salivary alpha-amylase).

Our team member Stefanie Hirsch just published her first paper! πŸŽ‰

The protocol describes an ecological momentary music intervention for stress reduction in chronically discriminated against Turkish immigrant women.

Curious? Follow this link: doi.org/10.1136/bmjo...

#openaccess

12.05.2025 11:37 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

Caution that this is a modeling study not a clinical trial, performing annual multi-cancer early detection tests could produce 49% fewer late-stage cancer diagnoses and 21% fewer deaths within 5 yrs compared to usual care bmjopen.bmj.com/content/15/5...

12.05.2025 13:45 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Developing patient journey maps with Aboriginal and Torres Strait Islander peoples living with dementia or cognitive impairment and their carers: protocol | BMJ Open bmjopen.bmj.com/content/15/5...

12.05.2025 14:17 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Hot off the press! Our latest research shows that the availability of community pharmacies has declined in the past decade, with the most deprived areas in England 65% more likely to lose a pharmacy.

In BMJ Open: bmjopen.bmj.com/content/15/5...

#gischat #episky #publichealth #medsky #pharmsky

12.05.2025 10:05 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 2    πŸ“Œ 0
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Is undergraduate medical education contributing to the extreme health inequities faced by socially excluded groups? What do we know and what can we do about it?

Learning about Inclusion Health in undergraduate medical education: a scoping review bmjopen.bmj.com/content/15/4...

02.05.2025 12:52 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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NEW PAPER: Updated CONSORT-2025 for reporting randomised trials is now available in the @bmj.com @jama.com , @thelancet.bsky.social, @plos.org and @naturemedicine.bsky.social

β€”> www.bmj.com/content/389/...

#openscience #transparency #medsky #statssky #episky

15.04.2025 05:55 β€” πŸ‘ 56    πŸ” 40    πŸ’¬ 2    πŸ“Œ 3
National yearly cost of breast cancer screening in the USA and projected cost of advocated guidelines: a simulation study with life table modelling Objective The aim of this study was to estimate the total national direct cost of breast cancer screening from 2019 to 2022 and project the total national cost and average lifetime cost of screening p...

This paper is so important and shows how different approaches to screening can change the cost by 20 billion dollars. Being more targeted does just as much good and avoids screening burdens and extra costs for women. bmjopen.bmj.com/content/15/2...

08.04.2025 00:43 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
Development of the International Classification of Functioning, Disability and Health Core Sets for children and youth with deafblindness: protocol for a multistudy collaboration across regions of WHO Introduction While the International Classification of Functioning, Disability and Health (ICF) Core Sets have been developed for deafblindness across the lifespan, there are currently no Core Sets sp...

bmjopen.bmj.com/content/15/4...

08.04.2025 09:55 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Continuity of care with doctorsβ€”a matter of life and death? A systematic review of continuity of care and mortality Objective Continuity of care is a long-standing feature of healthcare, especially of general practice. It is associated with increased patient satisfaction, increased take-up of health promotion, grea...

The evidence shows that patients of *all ages and levels of health* benefit from continuity of care with the same GP. Wes’s claim that this is only important for older, sicker people is simply not backed up by the evidence bmjopen.bmj.com/content/8/6/...

08.04.2025 11:29 β€” πŸ‘ 30    πŸ” 13    πŸ’¬ 2    πŸ“Œ 4

bmjopen.bmj.com/content/15/3...

02.04.2025 09:53 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I, alongside Dr Mike Ryder at Lancaster University, have just published an article in BMJ Medical Humanities titled 'Role of science fiction in conceptualising the reproductive future: a linguistic and literary perspective'! It is open access and you can read it here - mh.bmj.com/content/earl... 1/3

27.03.2025 08:27 β€” πŸ‘ 10    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
Physiotherapy and Optimised Enteral Nutrition In the post-acute phase of critical illness (PHOENIX): protocol for a mixed methods feasibility randomised controlled trial Introduction Each year in the UK, 140 000 patients are discharged from intensive care units (ICUs) to general hospital wards, almost all with complex rehabilitation needs. 84% of patients still requir...

The protocol for our PHOENIX trial has been published today, evaluating the feasibility of optimised nutrition and enhanced Physiotherapy for survivors of critical illness #ICURehab bmjopen.bmj.com/content/15/3...

28.03.2025 06:31 β€” πŸ‘ 10    πŸ” 9    πŸ’¬ 1    πŸ“Œ 0
Association between expedited review designations and the US or global burden of disease for drugs approved by the US Food and Drug Administration, 2010–2019: a cross-sectional analysis Objectives Pharmaceutical innovation can contribute to reducing the burden of disease in human populations. This research asks whether products approved by the US Food and Drug Administration (FDA) fr...

Do the FDA expedite review for the drugs the world needs the most? Analysis indicates "no". bmjopen.bmj.com/content/14/3... @bentleysciindustry.bsky.social

31.03.2025 12:51 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
GPT for RCTs? Using AI to determine adherence to clinical trial reporting guidelines Objectives Adherence to established reporting guidelines can improve clinical trial reporting standards, but attempts to improve adherence have produced mixed results. This exploratory study aimed to ...

Reporting guidelines are useful, but it is challenging (and time-consuming) to check how well authors adhere to them. Is this a task for AI? Research at bmjopen.bmj.com/content/15/3... @profkarimkhan.bsky.social

31.03.2025 12:42 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
Evaluating the implementation of inclisiran in primary care: process evaluation interim findings from interviews with key stakeholders Objectives VICTORION-Spirit was a hybrid study designed to assess the feasibility of implementing inclisiran, a novel cholesterol-lowering treatment and behavioural support within primary care centres...

First ever use of Type I Hybrid design in a Phase IIIb space, harnessing #impsci upstream in the translational pathway to accelerate diffusion of innovations - new in BMJ open

bmjopen.bmj.com/content/15/2...

07.03.2025 11:40 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Communication Article regarding the importance of quality PPI work. It should form a core part of the research, and shouldn't be an afterthought. @drmroz.bsky.social

10.03.2025 08:32 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Prospective harmonisation of four international randomised controlled trials in Canada, China, India and South Africa: the Healthy Life Trajectories Initiative Objectives The Healthy Life Trajectories Initiative (HeLTI) is an international multistudy consortium that supports the development and integration of four randomised controlled trials (RCTs) conducte...

Delighted to share that our HeLTI consortium harmonization paper has been published! Click the link below to find more about the paper:

bmjopen.bmj.com/content/15/3...

07.03.2025 20:13 β€” πŸ‘ 0    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Image of a newborn baby yawning

Image of a newborn baby yawning

Our Baby Sleep Project Protocol is out now in the BMJ Open. Find out how we are investigating innovative tools for promoting safer sleep in families with infants at increased risk of SUDI.
bmjopen.bmj.com/content/15/2...

17.02.2025 10:27 β€” πŸ‘ 1    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Cohort profile: the Viral load Cohort North-East Lesotho (VICONEL) from 2016 to 2023 – cohort description, test volumes, predictors of viraemia and the road ahead Purpose The prospective Viral load Cohort North-East Lesotho (VICONEL) aims to support clinical management and generate scientific evidence to inform HIV care. Specifically, VICONEL allows for the mon...

πŸ§ͺ Insights from the VICONEL Cohort on HIV Care in Lesotho 🧡(1/54)

Check out the full cohort profile here: bmjopen.bmj.com/content/15/2...

14.02.2025 10:52 β€” πŸ‘ 0    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

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