Our lab is offering 3 PhD projects this year across 3 different topics: antibiotic resistance mechanisms, evolution of pathogenic bacteria, and fundamental mechanisms of gene regulation.
www.findaphd.com/phds/?Keywor...
@graingerlab.bsky.social
Bacterial chromosome biology, gene expression, pathogenicity... and football. www.graingerlab.com
Our lab is offering 3 PhD projects this year across 3 different topics: antibiotic resistance mechanisms, evolution of pathogenic bacteria, and fundamental mechanisms of gene regulation.
www.findaphd.com/phds/?Keywor...
@danielabarilla.bsky.social kicking off #BioPhyChrom2025 - a fantastic turn out too...
16.09.2025 10:52 โ ๐ 4 ๐ 1 ๐ฌ 0 ๐ 0'We show that the VqmAj homologs can indeed detect (host autoinducer) DPO and, in response, activate the lytic pathway. Our observation indicates that jVP882 is a member of a large family of globally-dispersed quorum-sensing-responsive temperate phages.'
www.biorxiv.org/content/10.1...
๐ข Dear lovers of prokaryotic chromosomes:
Registration for the Biology & Physics of Chromosomes meeting has been extended until 7 August โณ.
Join us!
@biophychrom.bsky.social
@danielabarilla.bsky.social
@damelab.bsky.social
@graingerlab.bsky.social
@biochemsoc.bsky.social
#microsky
Talk slots full but we can take late breaking poster abstracts until August 7th. Hope to see you in York to hear about your chromosome story ๐งฌ๐ฆ ๐งซ
www.eventsforce.net/biochemsoc/f...
@vslioy.bsky.social @damelab.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social @biophychrom.bsky.social
Left: Compound-promoter interaction network. Fifty-three significant compound-promoter interactions are shown as edges in a Sankey diagram connecting the compounds (left, source nodes) to the promoters (right, target nodes). Edge thickness represents mean Z-scores (nโ=โ8), while node size represents the total number of interactions. Right: Proposed model for the molecular mechanism of caffeine-ciprofloxacin antagonism. Caffeine triggers expression of MicF small RNA in a Rob-dependent manner, which then binds to the 5โฒ-UTR of ompF mRNA to inhibit and decrease OmpF protein levels. This ultimately prevents ciprofloxacin from entering the cell, resulting in caffeine-ciprofloxacin antagonism
How are bacterial transport machineries regulated by external cues? @brochadolab.bsky.social &co identify environmental chemicals that regulate #transporter transcription, identifying the TF Rob as a key modulator of #EffluxPump expression in #Ecoli #AMR @plosbiology.org ๐งช plos.io/46pUM9Q
23.07.2025 09:20 โ ๐ 35 ๐ 13 ๐ฌ 1 ๐ 0Poster advertising the Biology and Physics of Prokaryotic Chromosomes conference that will be held in York, 16-19 September 2025.
Just few days left to register for this chromosome biology fรชte! ๐งฌ๐งฌ๐งฌ
โณ๐ 16 July
www.eventsforce.net/biochemsoc/f...
@vslioy.bsky.social @damelab.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social @biophychrom.bsky.social
Flyer advertising The Biology and Physics of Prokaryotic Chromosome conference that will be held in York, 16-19 September 2025.
Chromosome Enthusiasts, join us at The Biology & Physics of Prokaryotic Chromosomes ๐งฌ! Friendly community, fantastic speakers line-up, grant writing session for ECRs. Early-bird deadline approaching soon.
@damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biophychrom.bsky.social
๐จ Out now!
West African South American pandemic Vibrio cholerae encodes multiple distinct phage defence systems
#MicroSky ๐ฆ #Phage @mblokesch.bsky.social
www.nature.com/articles/s41...
Join us in York for the Biology & Physics of Prokaryotic Chromosomes! ๐งฌ #Microsky #Archaeasky
www.biochemistry.org/events-and-t...
@biochemsoc.bsky.social
@damelab.bsky.social @graingerlab.bsky.social @vslioy.bsky.social
Fascinating new PLoS Biology paper from George Schaible et al in the Hatzenpichler Lab at Montana State
โ๐๐ด ๐ต๐ฉ๐ฆ ๐ฐ๐ฏ๐ญ๐บ ๐ฆ๐น๐ข๐ฎ๐ฑ๐ญ๐ฆ ๐ฐ๐ง ๐ฃ๐ข๐ค๐ต๐ฆ๐ณ๐ช๐ข ๐ต๐ฉ๐ข๐ต ๐ฆ๐น๐ฉ๐ช๐ฃ๐ช๐ต ๐ฐ๐ฃ๐ญ๐ช๐จ๐ข๐ต๐ฆ ๐ฎ๐ถ๐ญ๐ต๐ช๐ค๐ฆ๐ญ๐ญ๐ถ๐ญ๐ข๐ณ๐ช๐ต๐บ, ๐๐๐ ๐ฑ๐ณ๐ฐ๐ท๐ช๐ฅ๐ฆ ๐ข๐ฏ ๐ช๐ฎ๐ฑ๐ฐ๐ณ๐ต๐ข๐ฏ๐ต ๐ฆ๐น๐ข๐ฎ๐ฑ๐ญ๐ฆ ๐ฐ๐ง ๐ฑ๐ฐ๐ด๐ด๐ช๐ฃ๐ญ๐ฆ ๐ฎ๐ฆ๐ค๐ฉ๐ข๐ฏ๐ช๐ด๐ฎ๐ด ๐ฃ๐ฆ๐ฉ๐ช๐ฏ๐ฅ ๐ต๐ฉ๐ช๐ด ๐ฑ๐ณ๐ฐ๐ง๐ฐ๐ถ๐ฏ๐ฅ ๐ด๐ต๐ฆ๐ฑ ๐ช๐ฏ ๐ญ๐ช๐ง๐ฆโ๐ด ๐ฆ๐ท๐ฐ๐ญ๐ถ๐ต๐ช๐ฐ๐ฏ๐ข๐ณ๐บ ๐ฉ๐ช๐ด๐ต๐ฐ๐ณ๐บ ๐ฐ๐ฏ ๐๐ข๐ณ๐ต๐ฉโ
We loved being back on campus for Master's hour on team working! @unibirmingham.bsky.social
The students created content to highlight the excellent research from one of our customers! It's all about the Long Reads ๐ @graingerlab.bsky.social @fozzz21.bsky.social @imibirmingham.bsky.social #MicroSky
Super excited to share the peer-reviewed version of the KorAB paper. Amazing to work such talented collaborators and thanks to the reviewers for making the work even better!
www.nature.com/articles/s41...
If you're interested in chromosome biology (DNA folding, gene regulation, replication, polymer modelling and more) we're organising the below this autumn. It'd be great to see you there. Please share if you can. :-)
21.01.2025 19:49 โ ๐ 27 ๐ 29 ๐ฌ 0 ๐ 42x professorships available in Manchester Institute of Biotechnology including in Microbial Engineering area (broadly defined to include microbiomes, environmental biotech etc) โ join us!
www.jobs.manchester.ac.uk/Job/JobDetai...
PhD projects available in our lab all listed in the below link. All focus on bacterial gene regulation, in the context of basic understanding, disease, or antibiotic resistance. Deadlines in January...
www.findaphd.com/phds/?Keywor...