Michael Cilento

www.nature.com/articles/s41...

Overall survival and quality of life with [177Lu]Lu-PSMA-617 plus enzalutamide versus enzalutamide alone in metastatic castration-resistant prostate cancer (ENZA-p): secondary outcomes from a multicen... The addition of [177Lu] Lu-PSMA-617 to enzalutamide was associated with improved survival and some aspects of HRQOL in patients with high-risk metastatic castration-resistant prostate cancer. Our find...

www.thelancet.com/journals/lan...

Final Overall Survival and Molecular Data Associated with Clinical Outcomes in Patients Receiving Ipatasertib and Abiraterone in the Phase 3 IPATential150 Trial In the phase 3 IPATential150 trial, ipatasertib addition to abiraterone significantly reduced the risk of disease progression in men with metastatic c…

www.sciencedirect.com/science/arti...

Our paper is out in @jclinical-invest.bsky.social 🎉 A great piece of collaborative science with Leigh Ellis and Chris Sweeney, looking at the role of tristetraprolin in #prostatecancer phenotypic plasticity (plus journal cover art by yours truly!) www.jci.org/articles/vie...

Evolution of myeloid-mediated immunotherapy resistance in prostate cancer - Nature Single-cell profiling of human prostate cancer and studies in mouse models show that macrophages expressing SPP1 mediate immunotherapeutic resistance through adenosine pathway activation and repr...

Congrats to Larry, Aram et al on latest prostate cancer immunology effort, now out in @natureportfolio.bsky.social - fun collaboration + more to come! @danafarber.bsky.social @ucsfcancer.bsky.social www.nature.com/articles/s41...

Single cell and spatial transcriptomics highlight the interaction of club-like cells with immunosuppressive myeloid cells in prostate cancer - Nature Communications The prostate cancer tumour microenvironment in the context of treatment remains to be explored. Here, single-cell RNA-sequencing and spatial transcriptomics analysis of samples at multiple treatment p...

Single cell and spatial transcriptomics highlight the interaction of club-like cells with immunosuppressive myeloid cells in prostate cancer.

doi.org/10.1038/s414...

Spatial transcriptomics in cancer research and potential clinical impact: a narrative review - Journal of Cancer Research and Clinical Oncology Spatial transcriptomics (ST) provides novel insights into the tumor microenvironment (TME). ST allows the quantification and illustration of gene expression profiles in the spatial context of tissues,...

doi.org/10.1007/s004...

Ok Not really sure what I’m doing but this #ProstateCancer starter pack has been created

It is meant to be INclusive so please let me know if you know anyone who wants so “join”

@asharpmedonc.bsky.social @nimasharifimd.bsky.social @alison-tree.bsky.social @profiand.bsky.social

go.bsky.app/ANw3D3j

Genitourinary oncology starter pack https://go.bsky.app/DtoXvaD

GU starter pack… started!
Let me know if you want to be added.
go.bsky.app/DtoXvaD

#Genitourinary #Oncology #GUonc #ProstateCancer #KidneyCancer #Urothelial #BladderCancer #PenileCancer #TesticularCancer #pcsm #kcsm #blcsm #tcsm #Medsky #Medtwitter

co-signed.

🌟Support SAiGENCI Cancer Research and help fund groundbreaking science! Plus, you can double your impact through matched giving on Giving Day! Let's make a lasting impact together. 💪🌍 #UoAGivingDay #UAMakeHistory Donate now!

How can #spatial biology/tech help people living with cancer? In our review published #OpenAccess @SpringerNature we highlight the latest insights being made with #ST spatial transcriptomics in cancer #research! 🧬🔬
👉🔗
@ChrisSweens1 @LisaButler5

Single-cell RNA sequencing of human prostate basal epithelial cells reveals zone-specific cellular populations…

Great to see the power of #spatial being used in more comparative analyses (not just descriptive), like this #GeoMx data looking at unique features of CAFs in early onset CRC!

Interesting big-picture perspective about the important issue of research biopsies, I’m always amazed by the altruism of people living with cancer in this space.

Over $17K raised for SAiGENCI Cancer Research on #UoAGivingDay!! Huge thank you to everyone who contributed 🤩

Proud to be an ambassador for @SAiGENCI Cancer Research this week! 🔬🧪🌟 You can have double the impact by donating tomorrow on #UofAGivingDay!! where all gifts this Tuesday will be matched up to $10,000!

Excited to finally make my debut on X, as I delve into the world of #CancerResearch! 🔬🧬👨‍🔬