Brian J. Gadd

Completely ignorant here - why in the world isn't this something NCBI does?!

It was mentioned during the question period. RFK Jr called it a canard.... So, there's that...

#medsky #immunosky #episky #pedsky #idsky

My colleagues and I have completed our review of the obscenity that was this ACIP meeting. You can download it here (it's free after you answer the questions)

www.evicollective.org/tec-briefs

Thanks for this. Any chance you have time stamps for each of the claims you documented here?

New post on the original culture war: kucharski.substack.com/p/the-origin...

*on things where they have more limited knowledge/understanding themselves.

Bingo. One exercise - have them do this with a topic they have some good understanding of and where you find ChatGPT errors...it will help them gauge just how cautious they need to be when using it on things they have limited more knowledge...

Kulldorf: "So the vote today is for seasonal influenza vaccines, not for a pandemic, because there's no such vaccines currently on the market. I think. So that the future meetings of ACIP and CDC will have to consider those things."

t.co/G6GMXlTNm5

This exact question was brought up at the June ACIP meeting. Kulldorf declined to address the question since it wasn't being voted on ("and because there is no such thing currently on the market").

Relatedly - factors that influence viral aerostability by ukhadds.bsky.social, (including the role of humidity & CO2).

bsky.app/profile/ukha...

He was fixated on the higher number of deaths in vaccine arms for multiple trials on the RSV monoclonals regardless of other findings. He said he would give them to his infant if they had an underlying condition, but not if they were healthy. Meissner basically layed into him for that.

He seemed to ignore that they were balanced (ex officio and Merck rep also stated the rates), and was impervious to the fact that Merck's 3rd party evaluator and the FDA found no association between the products and deaths and the working group, as Meissner made clear, found no cause for concern.

This was absolutely mind boggling to me. He kept acknowledging the 2:1 randomization but also kept pointing out that the vaccine arms had higher numbers of death in prior clinical studies of nirsevimab (already approved, not being voted on),

Sang Woo (Daniel) Park and I are excited to share a new preprint, "Susceptible host dynamics explain pathogen resilience to perturbations" [1/8]

www.biorxiv.org/content/10.1...

Reports are 12 were dropped on Fordow....

Restrictions had unequal impacts, but the pandemic itself did too. - Boston Review Adam Kucharski responds to Stephen Macedo and Frances Lee.

New piece on why it’s unhelpful to characterise COVID debate as ‘lockdowns are bad’ vs ‘lockdowns are good’ when it was really about people who claimed that COVID was 100x less fatal than it was + optimal to have a massive epidemic immediately before vaccine… vs those who sense checked these claims.

@jsm2334.bsky.social has some thoughts here:

x.com/jsm2334/stat...

Ousted CDC vaccine adviser says RFK Jr.'s message is clear: ‘Scientific expertise is no longer of use’ Terminated CDC vaccine adviser Helen Chu spoke with STAT about her fears for the future of vaccine policy

ICYMI: Fired #ACIP member is deeply worried about the committee she worked years to get a seat on, and the future of vaccination policy and vaccine access in this country. www.statnews.com/2025/06/10/c...

HHS justifies decision to stop recommending Covid shots during pregnancy with studies supporting the shots’ safety The studies are cited in a document sent to lawmakers.

"The Department of Health and Human Services is circulating a document on Capitol Hill to explain its decision to remove the Covid-19 vaccine recommendation for pregnant women — citing studies that largely found the shot is safe." www.politico.com/news/2025/06...

Thanks to @ReporterGoodman
for this excellent piece.

A team of us compiled data on controlled vaccine trials: 258 so far (~1/2 of which used inert placebo), covering 45 antigens and 2.5M participants.

Claims that vaccines lack placebo trials are false. 1/2

We just had an article published in ACS Central Science on the how the pH of exhaled aerosol evolves over time.

As we’ve previously reported, respiratory aerosol pH (high pH!) is a driver of SARS-CoV-2 decay. Meaning, understanding the pH dynamics is important for estimating risk.

Check it out! I'm proud to unveil CellWalk 2 for Apple Vision Pro. Bring beautiful and immersive biology learning into your space.

@cellwalk.bsky.social 🧬🦠🍎
#science #applevisionpro #visionos #apple #wwdc25

Our preprint “How Malicious AI Swarms Can Threaten Democracy” is now online.

We show how coordinated multi-agent LLM swarms can infiltrate communities, craft synthetic grassroots “consensus,” and erode institutional trust—and what we can do now to stop it.

osf.io/preprints/os...

Promoting more transparent,  reproducible, rigorous research with carefully justified conclusions and uncertainty quantification is a great idea…

www.science.org/content/arti...

Determinants of SARS-CoV-2 outcomes in patients with cancer vs controls without cancer: a multivariable meta-analysis with genomic imputation This comprehensive meta-analysis indicates that patients with active cancer with SARS-CoV-2 have a higher risk of mortality and hospitalisation than those without cancer. The risk of death was compara...

'To our knowledge, this is the largest meta-analysis to date evaluating outcomes in patients diagnosed with or treated for active cancer within three years prior to their index SARS-CoV-2 case, and includes over 280,000 patients with cancer and more than 18 million controls.'

🤦step 1) finish reading given references. TY Ed. Curious about other outcomes as well.

Is there vaccine era data on this and other infection-related risks during pregnancy? Theres obviously good reason for transfer of Ab but I'm curious if/how the risk may have changed.

....delving into the the data, by eye and quick ImageJ check, I don't think Fig 1A supports the claim that spike disrupts the p53-MDM2 interaction....

Two thoughts: 1) the same way other stimuli alter p53 stability, via post transcriptional modification (discussed but not studied in this paper), and 2) I've found one pre-print that observed ~25% of spike in the nucleus (Sattar et al. 2022). but, it is missing some key experiments IMO, and ... 1/2

They're the worst!