Nezha Benabdallah

Opinion | I’m the Prime Minister of Spain. This Is Why the West Needs Migrants.

'The regularization effort underway in Spain actually began as a citizen-led initiative endorsed by more than 900 nongovernmental organizations, including the Catholic Church, and it has the support of business associations and trade unions alike.'

www.nytimes.com/2026/02/04/o...

Congratulations to @ezsociety.bsky.social Christiane Nüsslein-Volhard Award winner Liz Patton for her pioneering work with zebrafish models in melanoma research, outstanding scientific excellence, unwavering dedication to community service & shaping of learned societies 👉https://edin.ac/4r1an7d

RESEARCH PAPER: SOX2 phosphorylation during mitosis limits genomic damage
By Williams et al., and Steven Pollard
➡️ https://genesdev.cshlp.org/content/40/3-4/185.full

Edinburgh University
#sox2 #chromatin #neural #mitosis #stemcells #phosphorylation

This is for you – and a great opportunity – if you are establishing a group in Croatia, Czechia, Estonia, Hungary, Lithuania, Luxembourg, Poland, Portugal and Türkiye...

DOT1L provides transcriptional memory through PRC1.1 antagonism - Nature Cell Biology Neville, Ferguson et al. show that non-canonical Polycomb repressive complex 1.1-mediated gene silencing is antagonized by DOT1L and is required for the therapeutic efficacy of Menin and DOT1L inhibit...

www.nature.com/articles/s41...

happy i could be a part of this paper from the Gilan lab out now. Along with many other things, it provides strong evidence of chromatin memory for gene activation, and suggests that DOT1L is the missing link balancing the fast and slow arms of the MLL/Polycomb axis

Ad for a postdoc position in centromere biology with colorful chromosomes and centromeres made out of FIMO.

🧪 My lab has an opening for a postdoc position soon! Please share/get in touch!

Today in @natgenet.nature.com, we report a saturation genome editing study that systematically dissects the degron of β-Catenin, which contains 5 of the 25 most frequently mutated regions of the human cancer genome, and >70 recurrent missense mutations.

rdcu.be/e1Tvk

Congratulations Pradeep!

Check out our new findings showing BRD4's role in preventing the premature activation of developmental transcription factors via #Polycomb, providing new mechanistic insights into the pathogenesis of neurodevelopmental disorder #CdLS #NDDs, #chromatinopathies www.biorxiv.org/content/10.6...

An example of a voter suppression ad on Facebook. This ad was part of a Russian election interference campaign.

Exposure to voter suppression ads on Facebook—which targeted non-White residents of battleground states—was associated with a 1.9% decrease in voter turnout in the 2016 election, representing approximately 4.7 million fewer votes nationwide. In PNAS: https://ow.ly/HJGf50Y7FPG

📣 I'm excited to share our latest preprint!

We adapt and characterise a neurosphere-based CNCC differentiation protocol, and demonstrate utility for quantitative phenotyping and craniofacial disease modelling! 🧫

Read about Array-CNCC here:
www.biorxiv.org/content/10.6...

@uoe-igc.bsky.social

Synovial sarcoma is driven almost exclusively by a single oncofusion – SS18-SSX

For years, the assumptions on disease mechanisms were simple:

➡️ SS18-SSX works by hijacking SWI/SNF chromatin remodeling activity

Our new study shows that assumption was wrong 🧵👇

www.biorxiv.org/content/10.6...

I did not know she was on Bluesky, but this whole work was led by @afroditisotiriou.bsky.social, a truly talented scientist that will finish her PhD this year and has not started looking for postdoc positions yet...

Also very cool co-ordinated back-to-back with a sister preprint from colleagues (and office mate) @gerrybrien.bsky.social reporting the same finding 🤝
www.biorxiv.org/content/10.6...

SS18::SSX activates Polycomb target genes without BAF ❌
Instead, transcription relies on EP300 via the SS18 QPGY domain
www.biorxiv.org/content/10.6...
➡️ Coactivator targeting emerges as a new therapeutic strategy in synovial sarcoma 🎯
Team work from @banitolab.bsky.social and @uoe-igc.bsky.social

Anyone know anything about Jennifer Harvey, who first isolated the virus containing HRAS (Harvey-Ras) at Mill Hill in 1967?

Prepping a lecture including the discovery of Ras oncogenes and wanted to add pics of the scientists involved.

The Internet has NOTHING

#sciencehistory #forgottenwomen

Very cool! Can't wait to see single-cell TimeVault 🤩

A genetically encoded device for transcriptome storage in mammalian cells Understanding how cells make decisions over time requires the ability to link past molecular states to future phenotypic outcomes. We present TimeVault, a genetically encoded system that records and s...

🧬🔬@science.org A genetically encoded device for #transcriptome storage in mammalian cells | Science www.science.org/doi/10.1126/... @broadinstitute.org

Yes, this is where you would work (the round building, not the boat)

We are looking for a postdoc to join our team! If you're interested in translating a cutting edge genomics technology (www.nature.com/articles/s41...) to real-life applications in hematology, this is for you. We offer a unique working environment ON THE BEACH: recruitment.crg.eu/content/jobs...

EASTBIO - Dissecting CIC::DUX4 oncogenic circuitry through single-cell perturbation profiling and network inference at University of Edinburgh on FindAPhD.com PhD Project - EASTBIO - Dissecting CIC::DUX4 oncogenic circuitry through single-cell perturbation profiling and network inference at University of Edinburgh, listed on FindAPhD.com

We have an exciting PhD opportunity through the EASTBIO programme, co-supervised with Diego Oyarzún. This project combines synthetic and systems biology to uncover the gene-regulatory circuitry hijacked in a cancer model. We’re looking for candidates with a strong interest in functional genomics.

Why we made Affinity free, and how we’ll keep it that way We’ve made Affinity completely free, empowering professional designers with studio-grade creative software, supported by Canva’s sustainable ecosystem.

I'm a longtime fan of Affinity Designer as an affordable Illustrator-killer for figures, and... it's now free?! www.canva.com/newsroom/new...
Highly recommended if you're sick of paying Adobe $. Maybe Canva can buy NPG too and get rid of the OA fees.

Job opportunity postodoctoral research fellow closing 18th November 2025

📣Job Opportunity: Develop machine learning of cellular automata models with applications to in vitro developmental biology.
More info: edin.ac/49Mr7ZQ

Congratulations @nsbenab.bsky.social and fellow experts joining the Independent Scientific Advisory Panel! 👏
@cmvm-edinburghuni.bsky.social

Beautiful (jaw-dropping 😉) work from Hannah Long’s group revealing how Neandertal enhancers influence facial morphology!

I guess I need to apologize to the writers of Alien: Prometheus. it turns out scientists really do touch everything like that

🥁This Wednesday , in #FragileNucleosome seminar, we are excited to host @hannahlong.bsky.social and @jeffvierstra.bsky.social to tell us about amazing work they are doing!
🗓️Register here for upcoming session and the entire series:
us06web.zoom.us/webinar/regi...

Promoter-proximal gatekeepers restrict pleiotropic enhancer inputs to achieve tissue specificity Developmental enhancers are central regulatory elements that can activate multiple genes, yet how they selectively regulate one gene over its neighbours remains unclear. Using the Drosophila twist E3 ...

Ever wondered what drives enhancer-promoter specificity? Why would an enhancer activate one gene rather than another neighboring one?

Check our latest preprint, led by @mmasoura.bsky.social, to find out!
www.biorxiv.org/content/10.1...

Enhancer-promoter compatibility is mediated by the promoter-proximal region Gene promoters induce transcription in response to distal enhancers. How enhancers specifically activate their target promoter while bypassing other promoters remains unclear. Here, we find that the p...

What is a promoter? And how does it work?

We very happy to share our latest work trying to understand enhancer-promoter compatibility.
I am very excited about the results of @blanka-majchrzycka.bsky.social, which changed the way I think about promoters

www.biorxiv.org/content/10.1...

Programmable promoter editing for precise control of transgene expression - @mitcheme.bsky.social @mitdeptofbe.bsky.social go.nature.com/4h9wlR1

🦖 Something HUGE just hatched.

Plasmidsaurus now offers RNA sequencing for gene expression analysis:
• As fast as 3 day turnaround
• $50/sample for academia, $80 for industry
• Up to ~10M unique transcript 3’ end reads per sample
• Interactive results

Explore Plasmidsaurus RNA-Seq today.