Dario Cantù

Excited to share our now @newphyt.bsky.social paper on the Genetic Basis of Microbiome Recruitment in Grapevine - a cool collaboration with @cantulab.bsky.social! 🍇🦠🧬

➡️ doi.org/10.1111/nph....

Here are some highlights: 🧵

GrepeGenomics @grapegenomics.bsky.social and
#Grapedia are now integrated via orthology between #CabernetSauvignon and #PN40024: a brand new synteny viewer and direct links to orthologs in the PN40024 gene catalogue hosted on #PlantaeViz by @jtmatus.bsky.social

Some months later, work is now published @natcomms.nature.com www.nature.com/articles/s41...

Phased epigenomics and methylation inheritance in a historical Vitis vinifera hybrid Epigenetic modifications, such as DNA methylation, regulate transcription and influence key biological traits. While many efforts were made to understand their stability in annual crops, their long-te...

Fresh from the lab: www.biorxiv.org/content/10.1.... We describe long-term conservation of haplotype-specific methylation patterns in clonal lineages, resolving mapping bias, collapsed haplotypes, and structural variation using a novel phased, graph-based approach.

Congrats to all elected as new fellows of AAAS including from @ucdavis.bsky.social:

Dawn Sumner, Dario Cantù, Huaijun Zhou, Frederic Chedin, Stephanie Hampton, Raissa M. D'Souza, Simona Ghetti, and Alexander Aue.

Assistant Professor of Applied Viticulture University of California, Davis is hiring. Apply now!

New faculty job at UC Davis! We are recruiting an Assistant Professor of Applied Viticulture, based at the Oakville research station in the heart of Napa Valley. A dream job for anyone passionate about viticulture and industry outreach. Apply by March 15.

recruit.ucdavis.edu/JPF06900

Assistant Professor of Sensory Science University of California, Davis is hiring. Apply now!

Applications for the Assistant Professor of Sensory Science are open until January 15.

Sensory scientists, apply on time!

No prior experience in wine is required.

Please share widely.

recruit.ucdavis.edu/JPF06782

The wild side of grape genomics With broad genetic diversity and as a source of key agronomic traits, wild grape species (Vitis spp.) are crucial to enhance viticulture’s climatic resilience and sustainability. This review discusses how recent breakthroughs in the genome assembly and analysis of wild grape species have led to discoveries on grape evolution, from wild species’ adaptation to environmental stress to grape domestication. We detail how diploid chromosome-scale genomes from wild Vitis spp. have enabled the identification of candidate disease-resistance and flower sex determination genes and the creation of the first Vitis graph-based pangenome. Finally, we explore how wild grape genomics can impact grape research and viticulture, including aspects such as data sharing, the development of functional genomics tools, and the acceleration of genetic improvement.

🍇 Dario Cantu, Mélanie Massonnet and Noé Cochetel collaborated on ways wild grape #genomics unlocks climate resilience for viticulture. Advances in pangenomics & haplotype analysis reveal traits for disease resistance, adaptability, & sustainability.
▶️ www.cell.com/trends/genet...
#ClimateAdaptation

Happy to share the final program for the Grape Genomics Workshop #PAG32 (aka Grape Genome Initiative) 🍇

An exceptional lineup of international speakers covering genome editing, genomic selection, epigenomics, and gene regulatory networks.

plan.core-apps.com/pag32/event/...

Grapegenomics is now live on BlueSky, all the news related to grapegenomics.com will be posted here. Follow to stay up to date on new grape, pathogen, and pest data!

Step 1

Getting there!

Our results support a model where, in an ancestor of Vitis and Muscadinia, mutations within a highly conserved region associated with flowering in angiosperms led to the emergence of dioecy in this lineage

Promoter variations in VviYABBY3 and expression profile in flowers suggest its role as a female suppressor in muscadines, similar to Vitis.

Unlike in Tetrastigma, in Muscadines flower sex is controlled by the same SDR as in Vitis with highly conserved boundaries and the same sex candidate genes

Whole genome sequencing and phasing of the SDR in Vitaceae show high gene content conservation in the family with size variations due to repetitive elements.

Conservation analysis reveals a collinear window with elevated gene conservation in the Vitis SDR across angiosperms.
pbs.twimg.com/media/GcIRnb...

Evolutionary history of the grape sex-determining region in angiosperms and emergence of dioecy in Vitaceae Dioecy, defined by the presence of either female or male flowers on separate individual plants, is rare in angiosperms. However, it has independently evolved multiple times from hermaphroditic ancesto...

New preprint from the lab biorxiv.org/content/10.1... describing the conservation of the grape sex determining region (SDR) across angiosperm genomes and detailed history within Vitaceae leading to dioecy in Vitis and Muscadinia. Collaboration with