Dubcovsky Lab 's Avatar

Dubcovsky Lab

@dubcovskylab.bsky.social

Updates from Jorge Dubcovsky's lab at UC Davis Account run by students and postdocs https://dubcovskylab.ucdavis.edu/home

94 Followers  |  24 Following  |  7 Posts  |  Joined: 23.01.2025  |  1.5541

Latest posts by dubcovskylab.bsky.social on Bluesky

Post image

Talking Biotech 467 - #Celiac safe wheat? Less immunoreactive wheat has been developed by
@UCDavisPlants using old-school mutagenesis. A scintillating talk with grad student Maria Rottersman.
@ASPB
share.transistor.fm/s/9419052e

12.07.2025 05:44 β€” πŸ‘ 14    πŸ” 7    πŸ’¬ 2    πŸ“Œ 1
Preview
Old Tricks, New Wheat for Celiacs - Maria Rottersman SummaryIn this episode of the Talking Biotech Podcast, Kevin Folta...

πŸŽ™οΈ Just published a new episode of Talking Biotech with Dr. Kevin Folta: Old Tricks, New Wheat for Celiacs - Maria Rottersman. Have a listen:

12.07.2025 05:00 β€” πŸ‘ 9    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
Preview
Targeting Gluten: Researchers Delete Proteins in Wheat Harmful to People with Celiac Disease A UC Davis study found that deleting a cluster of genes in wheat may reduce wheat allergies without harming breadmaking.

🌱 From UC Davis: Deleting key gliadin genes boosts wheat gluten strength & cuts celiac-triggering epitopesβ€”without harming yield. (Maria Rottersman, Jorge Dubcovsky)
▢️ www.ucdavis.edu/food/news/ta...

05.05.2025 16:23 β€” πŸ‘ 41    πŸ” 10    πŸ’¬ 1    πŸ“Œ 2
Deletion of wheat alpha-gliadins from chromosome 6D improves gluten strength and reduces immunodominant celiac disease epitopes

New work from a graduate student, Maria Rottersman, and others in the lab demonstrates that deleting the alpha-gliadins on chromosome 6D of wheat improves gluten strength and produces less celiac disease epitopes. Check it out now in Theoretical and Applied Genetics: rdcu.be/egXZ2

09.04.2025 04:18 β€” πŸ‘ 10    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
A high-quality genome assembly of the durum wheat landrace PI 192051. a Circular diagram showing the assembly features of PI 192051. The tracks, arranged from outermost to innermost, include: (i) chromosomes, (ii) GC content, (iii) gene density, and (iv) syntenic connections between A and B subgenomes. b Comparison of genome assembly quality (contig N50) between PI 192051and other published tetraploid (turquoise blue) and hexaploid (pink) wheat genomes. The horizontal axis represents the year, and the vertical axis represents the contig N50 size. Each circle represents one genome, with the diameter of the circle corresponding to the genome size. PI 192051 is highlighted with a red arrow. c Syntenic blocks among T. urartu (G1812 v2.0), T. monococcum (PI 306540), T. durum (PI 192051 and Svevo v1.0), T. dicoccoides (Zavitan v1.0), Ae. searsii (TE01), Ae. speltoides (TS01), and the A/B subgenomes of the bread wheat variety Chinese Spring (CS, RefSeq v2.1). Each line represents a syntenic block of 15 or more gene pairs with β‰₯ 80% identity.

A high-quality genome assembly of the durum wheat landrace PI 192051. a Circular diagram showing the assembly features of PI 192051. The tracks, arranged from outermost to innermost, include: (i) chromosomes, (ii) GC content, (iii) gene density, and (iv) syntenic connections between A and B subgenomes. b Comparison of genome assembly quality (contig N50) between PI 192051and other published tetraploid (turquoise blue) and hexaploid (pink) wheat genomes. The horizontal axis represents the year, and the vertical axis represents the contig N50 size. Each circle represents one genome, with the diameter of the circle corresponding to the genome size. PI 192051 is highlighted with a red arrow. c Syntenic blocks among T. urartu (G1812 v2.0), T. monococcum (PI 306540), T. durum (PI 192051 and Svevo v1.0), T. dicoccoides (Zavitan v1.0), Ae. searsii (TE01), Ae. speltoides (TS01), and the A/B subgenomes of the bread wheat variety Chinese Spring (CS, RefSeq v2.1). Each line represents a syntenic block of 15 or more gene pairs with β‰₯ 80% identity.

🌱From a Nature Portfolio preprint: Cloning of Lr30 reveals it’s identical to Lr.ace-4A and encodes a unique NLR gene conferring strong rust resistance in durum #wheat, but less so in hexaploid. (Jorge Dubcovsky)
▢️ www.researchsquare.com/article/rs-6...
#PlantScience #PlantImmunity

01.04.2025 15:46 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
Preview
Public Statement on Supporting Science for the Benefit of All Citizens TO THE AMERICAN PEOPLE We all rely on science. Science gave us the smartphones in our pockets, the navigation systems in our cars, and life-saving medical care. We count on engineers when we drive acr...

Please read this statement supporting science from members of US National Academies of Science, Engineering, and Medicine. It’s important we stand against these egregious cuts to science.

01.04.2025 17:08 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
Opinion | Why Did Elon Musk Go After Bunkers Full of Seeds? Gene banks are like a survivalist cache: our nation’s safeguard against all future challenges to growing the food we need.

Check out this article by a previous lab member, Iago Hale, on the impact of cuts to the USDA germplasm system. Definitely worth a read! www.nytimes.com/2025/03/22/o...

23.03.2025 23:17 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Preview
Blocking the scissors: New genetic tool makes grain breeding faster Scientists have developed a new genetic tool that makes it easier and faster to breed grains that grow more efficiently and are better adapted to different environments. They're using a ground-breakin...

Check out our work on fine-tuning miRNA control of plant height in wheat and triticale, as covered by the folks at the plant sciences department! www.plantsciences.ucdavis.edu/news/deberna...

14.03.2025 22:09 β€” πŸ‘ 12    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
Preview
Single cell analysis of wheat spike development | Plantae This preprint wins the award for β€œmost beautiful paper” this week. Xu, Lin et al. carried out an expression analysis of developing wheat spikes at three developmental stages, using both single-cell…

Plant Science Research Weekly -- Single cell analysis of wheat spike development (bioRxiv) @dubcovskylab.bsky.social (Summary by Mary Williams @PlantTeaching.bsky.social ) buff.ly/O6elukV

#PlantaePSRW

14.03.2025 14:15 β€” πŸ‘ 18    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
Three stages of wheat spike development with color-coded labels showing gene expression clusters. Several structures are visible clearly changing in form and gene expression pattern between the three developmental stages.

Three stages of wheat spike development with color-coded labels showing gene expression clusters. Several structures are visible clearly changing in form and gene expression pattern between the three developmental stages.

#PlantSci Research Weekly March 7 plantae.org/plant-scienc... (2/2) Single-cell analysis of wheat spikelet; Autoactivated calcium channel enhances symbiosis; Fungal pathogen hijacks phosphate signaling; Erucamide inhibits the type III secretion system; How Rhodanobacter R179 evades plant immunity

07.03.2025 07:31 β€” πŸ‘ 11    πŸ” 5    πŸ’¬ 1    πŸ“Œ 1
Spatial cell clusters based on the expression of 99 genes analyzed by smFISH at three stages of wheat spike development.

Spatial cell clusters based on the expression of 99 genes analyzed by smFISH at three stages of wheat spike development.

Expression profiles of genes differentially expressed during spikelet development.

Expression profiles of genes differentially expressed during spikelet development.

We’re excited to share our new preprint on wheat spike development! We used spatial transcriptomics and scRNA-seq to take a closer look at the different cell types and expression domains during key developmental stages of the wheat spike. Check it out here:
www.biorxiv.org/content/10.1...

20.02.2025 17:39 β€” πŸ‘ 59    πŸ” 25    πŸ’¬ 0    πŸ“Œ 5
Preview
A triplicated wheat-rye chromosome segment including several 12-OXOPHYTODIENOATE REDUCTASE III genes influences magnesium partitioning and impacts wheat performance at low magnesium supply We previously reported a structural rearrangement between wheat (Triticum aestivum) and rye (Secale cereale) chromosomes 1BS/1RS that increased the do…

🌱 A wheat-rye chromosome rearrangement alters Mg partitioning between shoots and roots by increasing jasmonate biosynthesis, enhancing wheat tolerance to Mg scarcity. (Gilad Gabay, Jorge Dubcovsky)
▢️ www.sciencedirect.com/science/arti...
#PlantScience #Genomics #Wheat

18.02.2025 23:42 β€” πŸ‘ 12    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0

Congrats @cristobaluauy.bsky.social, incredible news!

14.02.2025 04:51 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

We’re excited to announce the recent publication from our lab was featured on the cover of the plant biotechnology journal! It demonstrates an approach for precisely controlling wheat and triticale plant height. Read the full paper here: onlinelibrary.wiley.com/doi/10.1111/...

29.01.2025 00:15 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

@dubcovskylab is following 19 prominent accounts