Luca Pezzullo

Your dignity honors the bravery of the Ukrainian people.

Be strong, be brave, be fearless.
You are never alone, dear President Zelenskyy.

We will continue working with you for a just and lasting peace.

A foundation model of transcription across human cell types - Nature A foundation model learns transcriptional regulatory syntax from chromatin accessibility and sequence data across a range of cell types to predict gene expression and transcription factor interactions...

A new large language of life model (LLLM) for the transcriptome that predicts gene expression within and across human cell types www.nature.com/articles/s41... @nature.com
For more on the remarkable surge of LLLMs see erictopol.substack.com/p/learning-t...

Working paper studying freelancers argues AI creates an "inflection point" for each job type.

Before that, AI boosts freelancer earnings (web devs saw a +65% increase). After, AI replaces freelancers (translators saw -30% drop). They suggest that once AI starts replacing a job, it doesn't go back.

“Through the screen, I found something unexpected: the chance for technology to offer a different — and sometimes deeper — interaction with patients.”
—@helenouyang.bsky.social
@nytopinion.nytimes.com
gift link www.nytimes.com/2024/12/27/o...

"Any moment might be our last. Everything is more beautiful because we're doomed. You will never be lovelier than you are now. We will never be here again."

A message for our time from Homer’s Iliad.

‼️"o1-preview demonstrates superhuman performance in differential diagnosis, diagnostic clinical reasoning, and management reasoning, superior in multiple domains compared to prior model generations and human physicians."

And this is using vignettes, not multiple choice. arxiv.org/pdf/2412.10849

Human behavior happens at a surprisingly slow 10 bits/second or so, even though our sensory systems gather 8 orders of magnitude more data. Plus, we can only think about one thing at a time. We don’t know why

(In LLM terms, human behavior happens at less than a token/sec). arxiv.org/abs/2408.10234

Basically think of the o3 results as validating Douglas Adams as the science fiction author most right about AI.

When given longer to think, the AI can generate answers to very hard questions, but the cost is very high, it is hard to verify, & you have to make sure you ask the right question first.

Among ~9 million Americans, representing over 440 occupations, who had the lowest proportion of #Alzheimer's disease related deaths?
Ambulance and taxi drivers
www.bmj.com/content/387/...
? benefit of spatial and navigational processing

Endlessly terrible news cycle around this company. Previously:

Can A.I. Be Blamed for a Teen’s Suicide? www.nytimes.com/2024/10/23/t...

An AI companion suggested he kill his parents. www.washingtonpost.com/technology/2...

Just a reminder that none of the people who make LLMs, no matter how smart, actually know what specific tasks LLMs will be good or bad at. We are barely benchmarking these systems at all on any sorts of tasks.

You should explore in areas of your expertise to try to figure it out for your use cases.

"Quantity", when at sufficient high levels, becomes "Quality" (a change in the underlying processes): Generative AI produces functional and operational changes in this way.

Thank you for sharing.

Perfect explanation :-)

Very interesting work, @maxboot.bsky.social About 40 years later, the GOP is deeply different...

Yes, measure the middle of one piece (folding it on itself), then put them in line, and put on fire the first one. When the flames reach the middle of the second one, 45 minutes have passed...

Perfect 😅

Very good observation from @emollick.bsky.social : the technical / procedural competence and the functional / context-focused one are on different levels, in LLM use cases...

So, this result seems to confirm the previous observations: general LLM frontier models produce similar results, in terms of quality, as medically adapted ones when used in medical field...

These open questions are absolutely valid also for the AI impact on Psychological practice...

Just wait until conspiracy theorists discover they’re part of a conspiracy to use conspiracy theorists to spread disinformation via conspiracy theories.

The "Personal Tutor" use case is one of the most powerful LLM application to date.
It has the potential to substantially restructure and innovate the Education field.

Like ‘old Twitter’: The scientific community finds a new home on Bluesky After recent changes to Elon Musk’s X, a gradual migration turns into a stampede

Scientific communities are shifting their own "Ideas & News exchange forum" from X to Bluesky... and seemingly with a rapid pace.

www.science.org/content/arti...

I mostly agree.

It’s definitely an escalation and designed to send a message to Kyiv

No, it’s not nuclear armageddon

Ukraine doesn’t have exoatmospheric interception capability, but they do have some terminal phase interceptors that may (heavy emphasis on may) be of some use vs Russian IR/ICBMs.

Very interesting theme... at the intersection of economics, technological development / innovation, and societal dynamics...

I would like to be added. Military psychology, cognitive security, stratcom / disinformation.

Interesting, but this isn't the first time...

Frankly embarassing... 🙄

Screenshot of an Irish Times article from 2011 with the headline "University in talks with Egypt over future of ancient mummy"

Screenshot of an Irish Times article from 2003 with the headline "UCC keeping 2.3 tonnes of uranium in basement store"

The fact that UCC hid a 3000-year-old mummy under the floorboards of a lecture theatre on a campus where two and a half tonnes of uranium rods were being stored in a basement nearby and DIDN'T end up with a zombie-pharaoh apocalypse is both a mystery and endlessly disappointing