Karl Grieshop's Avatar

Karl Grieshop

@karlgrieshop.bsky.social

Evolutionary genetics PI and professional reinventor of wheels @biouea.bsky.social @uniofeastanglia.bsky.social. #firstgen πŸ‡ΊπŸ‡Έ ➑️ πŸ‡ΈπŸ‡ͺ ➑️ πŸ‡¨πŸ‡¦ ➑️ πŸ‡ΊπŸ‡Έ ➑️ πŸ‡¬πŸ‡§ | He/him | Posts are mine. grieshoplab.com

237 Followers  |  218 Following  |  8 Posts  |  Joined: 16.04.2025  |  2.2

Latest posts by karlgrieshop.bsky.social on Bluesky

Krebs or Davies... think it was Krebs, no?

17.10.2025 13:55 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

@biouea.bsky.social @nrpdtp.bsky.social

16.10.2025 13:57 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Molecular and genomic insights to sexually antagonistic genes (GRIESHOP_U26DTP) | Doctoral Training Partnership Why do harmful genes persist in populations instead of being removed by natural selection? One answer lies in sexual antagonism: when a genetic variant benefits males but harms females, or vice versa.

Please RT!

🚨 4-year PhD position in my lab (Oct 2026 start) 🚨

Molecular and genomic insights to sexually antagonistic genes

Application deadline: Dec 2, 2025

biodtp.norwichresearchpark.ac.uk/projects/mol...

16.10.2025 13:51 β€” πŸ‘ 12    πŸ” 21    πŸ’¬ 1    πŸ“Œ 0
Text: Society for the Study of Evolution Call for Proposals: Research Synthesis Working Groups. Deadline: January 6.

Text: Society for the Study of Evolution Call for Proposals: Research Synthesis Working Groups. Deadline: January 6.

Now accepting proposals for new Research Synthesis Working Groups! Each funded group will present a symposium at the Evolution meeting, collaborate on a publication, and establish a lasting research network. Submit your proposal by January 6: www.evolutionsociety.org/content/soci...

09.10.2025 07:22 β€” πŸ‘ 12    πŸ” 12    πŸ’¬ 0    πŸ“Œ 2

I'm the incoming SSE president and am behind this idea -- if you're interested in putting together an app and have questions, pls reach out!

11.10.2025 14:31 β€” πŸ‘ 48    πŸ” 32    πŸ’¬ 2    πŸ“Œ 0
FlyBase: Current Release FlyBase: a database for drosophila genetics and molecular biology

#FlyBase release FB2025_04 is live. There's a couple of major changes in this release.

First, we've added many new bulk files to the Downloads page. flybase.org/downloads/bu... (you can find descriptions of the contents and format of each file here wiki.flybase.org/wiki/FlyBase...)

03.10.2025 21:04 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
Population Genetics group 59

Exciting news!
The next #PopGroup meeting will take place in Lille 🍟, France, 7–9 January 2026 – just 1 hour by train from London, Brussels, and Paris.

This year, PopGroup will also host ALPHY, the annual meeting of Evolutionary Genomics.

More info: populationgeneticsgroup.org.uk

See you there !

29.09.2025 08:52 β€” πŸ‘ 45    πŸ” 53    πŸ’¬ 1    πŸ“Œ 2

Important heads up! This is crazy

15.09.2025 09:31 β€” πŸ‘ 0    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

Genome-wide associations of fitness components reveal antagonistic pleiotropy and sexual conflict in the Florida Scrub-Jay https://www.biorxiv.org/content/10.1101/2025.09.09.673786v1

13.09.2025 04:32 β€” πŸ‘ 9    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
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Dozens of heatwaves linked to carbon emissions from specific companies Nearly one-quarter of heatwaves would have been β€˜virtually impossible’ without global warming β€” and can be attributed to the emissions of individual energy producers.

Nearly one-quarter of heatwaves would have been β€˜virtually impossible’ without global warming β€” and can be attributed to the emissions of individual energy producers.

go.nature.com/3Iemuwm

10.09.2025 16:08 β€” πŸ‘ 49    πŸ” 22    πŸ’¬ 1    πŸ“Œ 4
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Leaving Academia: Insights from Evolutionary Biologists on Their Career Transitions and Job Satisfaction Many who have obtained PhDs in evolutionary biology will ultimately pursue careers that fall outside a narrow definition of an academic career. At the same time, PhD students and supervisors of PhD st...

β€œOverall, the message from this survey is positive; evolutionary biologists are readily employable outside of academia, generally well-prepared for those jobs, and report high levels of satisfaction” www.biorxiv.org/content/10.1...

10.09.2025 11:19 β€” πŸ‘ 41    πŸ” 19    πŸ’¬ 0    πŸ“Œ 1
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Assistant Professor Plant-Microbe Interactions We seek a creative, collaborative, and visionary plant biologist to establish an internationally recognized research program at the forefront of plant-microbe interactions aimed at understanding how t...

The Department of Biology at Colorado State University is hiring an Assistant Professor in the area of plant-microbe interactions! Please spread the word!

jobs.colostate.edu/postings/165...

08.09.2025 15:45 β€” πŸ‘ 74    πŸ” 138    πŸ’¬ 0    πŸ“Œ 1

bioRxiv bat signal. We had a huge influx of submissions around Labor Day and now have a backlog. If any affiliates are available to screen, we'd be eternally grateful!

04.09.2025 17:44 β€” πŸ‘ 22    πŸ” 19    πŸ’¬ 5    πŸ“Œ 0
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Only 10 days left to apply:

We are searching for a senior postdoc (3 +3 years) in the field of theoretical ecology and evolution.

The position provides the opportunity to closely interact with experimentalists and develop own research projects.

Please RT.

Details πŸ‘‡:
shorturl.at/iiiOv

01.09.2025 05:54 β€” πŸ‘ 26    πŸ” 43    πŸ’¬ 1    πŸ“Œ 3
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Asymmetry in Cross-Sex Cross-Trait Genetic Covariances and the Evolvability of Sexual Dimorphism | The American Naturalist Abstract The evolution of sexual dimorphism is predicted to resolve conflict that can arise from divergent evolutionary interests between sexes, enabling each sex to reach its fitness optimum. However...

Videlier and Sztepanacz re-analyse published data to show that sexual dimorphism may evolve as easily from indirect responses to sexually concordant selection as from direct responses to sexually antagonistic selection.

Read now ahead of print!
www.journals.uchicago.edu/doi/10.1086/...

30.08.2025 19:10 β€” πŸ‘ 8    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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GAUTIER Mathieu / baypass public Β· GitLab GitLab Community Edition

For those interested: πŸš€ BayPass v3.1 released!
πŸ”Ή Improved MCMC adaptive phase
πŸ”Ή Computation reduced >6X with default (recommended) options, while keeping similar accuracy
πŸ”Ή Plus other minor edits

πŸ“– Details in the manual / changelog
πŸ”— Repo: forge.inrae.fr/mathieu.gaut...

26.08.2025 14:50 β€” πŸ‘ 16    πŸ” 12    πŸ’¬ 0    πŸ“Œ 2

Please share broadly: I am looking for a postdoctoral fellow to work on a collaborative project on the temporal population genomics of invasive Capeweed (using contemporary and herbarium genomics), with β€ͺβ€ͺ@shaky-dingo.bsky.social‬ and colleagues

27.08.2025 12:09 β€” πŸ‘ 52    πŸ” 90    πŸ’¬ 3    πŸ“Œ 3
Dear Fly Community,

In May 2025, the NIH terminated all grant funding to Harvard University, including the NHGRI grant that supported FlyBase. This grant also funded FlyBase teams at Indiana University (IU) and the University of Cambridge (UK), and as a result, their subawards were also canceled.

The Cambridge team has secured support for one to two years through generous donations from the European fly community, emergency funding from the Wellcome Trust, and support from the University of Cambridge. At IU, funding has been secured for one year thanks to reserve funds from Thom Kaufman and a supplement from ORIP/NIH to the Bloomington Drosophila Stock Center (BDSC).

Unfortunately, the situation at Harvard is far more critical. Harvard University had supported FlyBase staff since May but recently denied a request for extended bridge funding. As a result, all eight employees (four full-time and four part-time) were abruptly laid off, with termination dates ranging from August to mid-October depending on their positions. In addition, our curator at the University of New Mexico will leave her position at the end of August. This decision came as a shock, and we are urgently pursuing all possible funding options.

To put the need into perspective: although FlyBase is free to use, it is not free to make. It takes large teams of people and millions of dollars a year to create FlyBase to support fly research (the last NHGRI grant supported us with more than 2 million USD per annum).

To help sustain FlyBase operations, we have been reaching out to you to ask for your support. We have set up a donation site in Cambridge, UK, to which European labs have and can continue to contribute, and a new donation site at IU to which labs in the US and the rest of the world can contribute. We urge researchers to work with their grant administrators to contribute to FlyBase via these sites if at all possible, as more of the money will go to FlyBase. However, we appreciate that some fu…

Dear Fly Community, In May 2025, the NIH terminated all grant funding to Harvard University, including the NHGRI grant that supported FlyBase. This grant also funded FlyBase teams at Indiana University (IU) and the University of Cambridge (UK), and as a result, their subawards were also canceled. The Cambridge team has secured support for one to two years through generous donations from the European fly community, emergency funding from the Wellcome Trust, and support from the University of Cambridge. At IU, funding has been secured for one year thanks to reserve funds from Thom Kaufman and a supplement from ORIP/NIH to the Bloomington Drosophila Stock Center (BDSC). Unfortunately, the situation at Harvard is far more critical. Harvard University had supported FlyBase staff since May but recently denied a request for extended bridge funding. As a result, all eight employees (four full-time and four part-time) were abruptly laid off, with termination dates ranging from August to mid-October depending on their positions. In addition, our curator at the University of New Mexico will leave her position at the end of August. This decision came as a shock, and we are urgently pursuing all possible funding options. To put the need into perspective: although FlyBase is free to use, it is not free to make. It takes large teams of people and millions of dollars a year to create FlyBase to support fly research (the last NHGRI grant supported us with more than 2 million USD per annum). To help sustain FlyBase operations, we have been reaching out to you to ask for your support. We have set up a donation site in Cambridge, UK, to which European labs have and can continue to contribute, and a new donation site at IU to which labs in the US and the rest of the world can contribute. We urge researchers to work with their grant administrators to contribute to FlyBase via these sites if at all possible, as more of the money will go to FlyBase. However, we appreciate that some fu…

https://wiki.flybase.org/wiki/FlyBase:Contribute_to_FlyBase

Our immediate goals are:

1. To maintain core curation activities and keep the FlyBase website online

2. To complete integration with the Alliance of Genome Resources (The Alliance).

Integration with the Alliance is essential for FlyBase’s long-term sustainability. For nearly a decade, NHGRI/NIH has supported the unification of Model Organism Databases (MODs) into the Alliance, which we aim to achieve by 2028. Therefore, securing bridge funding to sustain FlyBase over the next three years is crucial for successful integration and the long-term access to FlyBase data.

At present, our remaining funds will allow us to keep the FlyBase website online for approximately one more year. Beyond that, its future is uncertain unless new funding is secured. We will, of course, continue pursuing additional grant opportunities as they arise.

Given the uncertainty of future NIH or alternative funding sources, we are relying on the Fly community for support. Your contributions will directly help us retain the staff needed to complete this transition and to secure ongoing fly data curation into the Alliance beyond 2028.

We at FlyBase are incredibly grateful for the outpouring of support from the community during this challenging time. Your encouragement has strengthened our resolve and underscores how vital this resource remains to Drosophila research worldwide.

Sincerely,
The FlyBase Team

https://wiki.flybase.org/wiki/FlyBase:Contribute_to_FlyBase Our immediate goals are: 1. To maintain core curation activities and keep the FlyBase website online 2. To complete integration with the Alliance of Genome Resources (The Alliance). Integration with the Alliance is essential for FlyBase’s long-term sustainability. For nearly a decade, NHGRI/NIH has supported the unification of Model Organism Databases (MODs) into the Alliance, which we aim to achieve by 2028. Therefore, securing bridge funding to sustain FlyBase over the next three years is crucial for successful integration and the long-term access to FlyBase data. At present, our remaining funds will allow us to keep the FlyBase website online for approximately one more year. Beyond that, its future is uncertain unless new funding is secured. We will, of course, continue pursuing additional grant opportunities as they arise. Given the uncertainty of future NIH or alternative funding sources, we are relying on the Fly community for support. Your contributions will directly help us retain the staff needed to complete this transition and to secure ongoing fly data curation into the Alliance beyond 2028. We at FlyBase are incredibly grateful for the outpouring of support from the community during this challenging time. Your encouragement has strengthened our resolve and underscores how vital this resource remains to Drosophila research worldwide. Sincerely, The FlyBase Team

The community of Drosophila researchers is amazing, mutually supportive and collaborative. Right now a key resource for our community, @flybase.bsky.social , is threatened by the cancellation of its NIH grant and is seeking community help in raising short term funds 1/n πŸ§ͺ please share

23.08.2025 12:18 β€” πŸ‘ 152    πŸ” 128    πŸ’¬ 1    πŸ“Œ 8
Open Call for Expressions of Interest in Max Planck Directorships:
Expressions of interest can be submitted until 31 October 2025.

Open Call for Expressions of Interest in Max Planck Directorships: Expressions of interest can be submitted until 31 October 2025.

Director at Max Planck - a unique position! The Open Call for Expressions of Interest in Max Planck Directorships is open now and can be submitted by the 31st of October 2025. ➑️ mpg.de/directors - Please share the Open Call among potential candidates.

01.08.2025 09:06 β€” πŸ‘ 162    πŸ” 196    πŸ’¬ 1    πŸ“Œ 15
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EZ4 D Educational Stereo Microscope with Integrated LED llumination and Digital 3 MP Camera Educational Stereo Microscope with Integrated LED llumination and Digital 3 MP Camera

Anyone out there have a copy of the old @leicamicrosystems.bsky.social‬ "Firecam" software?

From the mid/late 2000s. I'm trying to resurrect a EZ4D with integrated camera, but the software for it seems to have disappeared from the internet...

www.leica-microsystems.com/products/lig...

27.07.2025 08:30 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 2    πŸ“Œ 1
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Tenure-track faculty search of the UCSF Biochemistry & Biophysics Department is open for applications!

We are looking for creative, innovative scientists asking fundamental questions in any area of biology.

Join our vibrant, collaborative, and supportive community!

aprecruit.ucsf.edu/JPF05702

23.07.2025 22:51 β€” πŸ‘ 85    πŸ” 71    πŸ’¬ 1    πŸ“Œ 2
Hibbins Lab

I'm recruiting students / postdocs to join my new lab at the University of Rochester for Fall 2025 onwards! If you're interested in phylogenetic comparative methods, genome evolution, and/or computational biology, please get in touch! More info:

mhibbins.github.io

02.10.2024 20:01 β€” πŸ‘ 49    πŸ” 58    πŸ’¬ 0    πŸ“Œ 2
CIG- UNIL

CIG- UNIL

Become our colleague! Tenure-track Assistant Professor position at The Center for Integrative Genomics, University of Lausanne, Switzerland. unil.ch/cig/en/home....
More details for how to apply are here:
www.nature.com/naturecareer...

21.07.2025 10:18 β€” πŸ‘ 42    πŸ” 60    πŸ’¬ 1    πŸ“Œ 2
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Evolutionary Ecologist - Williamstown, Massachusetts (US) job with Williams College - Biology Department | 674315 The Biology Department at Williams College, a premier liberal arts college with a strong commitment to excellence in the sciences, invites applicat...

🚨 TT JOB ALERT 🚨
Evolutionary Ecology
Williams College

21.07.2025 11:02 β€” πŸ‘ 9    πŸ” 18    πŸ’¬ 0    πŸ“Œ 0

Do you like to think about temporal niches and coexistence theory? Or perhaps you want to hear some really quirky natural history of marine insects & the moon? Or both? Read on: a mystery & its potential solution in two papers!

21.07.2025 05:44 β€” πŸ‘ 37    πŸ” 16    πŸ’¬ 1    πŸ“Œ 4
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Expression Divergence in Response to Sex-biased Selection Abstract. It remains debated whether greater degrees of sexual dimorphism would evolve if not for intersexual genetic constraints. Here, we used experiment

@karlgrieshop.bsky.social @aneil-agrawal.bsky.social @ruxmolnar.bsky.social et al. experimentally broke intersexual genetic constraints in Drosophila: male-limited chromosome inheritance increased male fitness and masculinized splicing.

πŸ”— doi.org/10.1093/molbev/msaf099

#evobio #molbio #drosophila

10.07.2025 16:33 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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The Xerces Society - Science Illustration Intern   JOB TITLE:  Science Illustration InternLOCATION:  Remote position. Candidates must have a personal office location suitable for work purposes, with broadband internet access, and must work from a city/state location approved by Xerces as their assigned work location.COMPENSATION: $24 per hourSTATUS & SCHEDULE: Part time, approximately 20 hours/week.DURATION:  September – December 2025 (Flexible based upon student’s academic schedule)APPLICATION DEADLINE:  July 14, 2025APPLICATION INSTRUCTIONS: All applications must be submitted via our application website at: xerces.org/jobsXerces provides accommodations for the job application process if needed. If you need an accommodation to complete the job application process, please email reasonable.accomodation@xerces.org with your specific request.JOIN US!The Xerces Society's science illustration internship program is generously supported by funding from the Maxwell/Hanrahan Foundation. At Xerces, we harness the knowledge of scientists and the enthusiasm of the public to implement conservation programs. We take action by helping farms and public agencies develop conservation plans for pollinators and beneficial insects, producing ground-breaking publications on insect conservation, training thousands of farmers and land managers to protect and manage habitat for beneficial insects, protecting endangered species and their habitat, and engaging the public to raise awareness about invertebrates found on farms, forests, prairies, deserts, streams, wetlands, towns and cities. Our methods focus on habitat conservation planning, education, scientific analysis, advocacy, and applied research to conserve invertebrates, such as bees, butterflies, mollusks, and fireflies. WHAT YOU’LL BE DOING: As the Scientific Illustration Intern for the Xerces Society, you will build your portfolio and gain experience in science illustration through creating visual media that advances public understanding of invertebrates and advocacy for their conservation. This is a remote position at 20 hours per week from September through December. The intern will be supervised by the communications director and work directly with many Xerces Society staff.ESSENTIAL JOB FUNCTIONS AND RESPONSIBILITIES:  Produce scientific illustrations, animations, and/or data visualizations of invertebrates and the conservation issues impacting them. Projects will include developing print and digital media for the Xerces’ Bring Back the Pollinators campaign.Work with the  communications team and conservation program staff to identify and produce visual storytelling opportunities for Xerces conservation initiatives. Participate in relevant staff meetings and events.Participate in occasional community science field work.Present and exhibit final illustrations through a Xerces Society venue. 

Job! Paid scientific illustration internship.

09.07.2025 13:05 β€” πŸ‘ 26    πŸ” 21    πŸ’¬ 0    πŸ“Œ 1

More details in the paper:

bsky.app/profile/karl...

09.07.2025 15:12 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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We also analysed sex-specific alternative splicing and found flies carrying chromosomes that underwent male-limited evolution had more male-like sex-specific alternative splicing profiles.

09.07.2025 15:10 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

@karlgrieshop is following 20 prominent accounts