Wanpen Vongpatanasin

Also welcome new Honorary JC member @k-bunsawat.bsky.social

Good HTN journal club today by @robynwei.bsky.social discuss effects of ultraprocessed food on cardiometabolic health @giaconajohn.bsky.social @hkkimphd.bsky.social Need to eat less UPF! www.nature.com/articles/s41...

⏳In 7 days an impt discussion on #BloodPressure across Womens #Lifespan coordinated by #NIH #NHLBI

There is still time to register👉🏻
web.cvent.com/event/e7c2bdc3…

Looking fwd to presenting & learning!

Hope you will join #CardioSky #MedSky

Multiple large natural experiments have documented Shingles vaccine is linked with ~20-25% reduced risk of dementia and Alzheimer's disease. A new report today adds to that and extends the to slowing the progression of dementia @cellcellpress.bsky.social
www.cell.com/cell/fulltex...

Teens may have come up with a new way to detect, treat Lyme disease using CRISPR gene editing To compete at iGEM, a sort of science Olympics, teens at a Georgia high school set their sights on finding a better way to detect and treat Lyme disease. Their approach uses CRISPR gene editing.

Remarkable story of a Georgia high school team who used CRISPR to make a rapid diagnostic test strip for Lyme disease, speeding dx from 2 weeks to days
www.cbsnews.com/news/teens-m...

Aldo on NEJM

It’s all aldosterone on the @nejm.org right now!

www.nejm.org/browse/speci...

🙌👇👏

#CardioSky #MedSky @cardioobdoc.bsky.social @aspcardio.bsky.social @cardioob.bsky.social @ahascience.bsky.social

Are you interested in #BloodPressure?

Please join me & the other invited speakers & moderators for #NHI #NHLBI online 2 Day Workshop!

Free Registration👉
web.cvent.com/event/e7c2bd...

1/ In this #OriginalResearch paper in @ahajournals.bsky.social, Bellamo et al evaluate Lp(a) as a prognostic marker for incident and secondary vascular disease in participants from the UK Biobank

Here's a🧵summarizing key aspects of paper

🔗http://bit.ly/3HkLhP6

Let’s unpack the findings ⤵️

Redefining the Genetic Architecture of Hypertrophic Cardiomyopathy: Role of Intermediate Effect Variants | Circulation Background: Hypertrophic cardiomyopathy (HCM) is a genetically heterogeneous disorder primarily linked to rare variants in sarcomere genes, though recently certain non-sarcomeric genes have emerged as...

🚨 New @CircAHA #ESC2025 SimPub alert!
🚨 HCM isn’t just driven by rare Mendelian mutations. This study highlights the role of intermediate-effect variants (IEVs)—variants with moderate effect & low penetrance—in shaping disease expression. #HCM #SoMeEditor

tinyurl.com/HCM-IEVs

1/ Should you be concerned about lead in your protein powder? Consumer Reports found elevated levels in several popular brands, causing influencers to spread the results of the report. So we asked Megan, an RN and our nutrition contributor for YLE, to break it down. Here’s what you need to know 👇

Thankful for the opportunity to visit Nara Women University with @hkkimphd.bsky.social to observe laboratory of Prof Miki and Yoshimoto who are pioneer in measurements of conscious renal and lumbar SNA recording. Never have my seminar brochure translated into Japanese before 😀 @utswim.bsky.social

Can’t stop staring at the prevalence of hypertension among young people.

www.ahajournals.org/doi/epub/10....

What ‘Secret Shoppers’ Discovered About IV Hydration Spas Researchers posed as potential clients to examine the practices and regulation of the burgeoning intravenous hydration spa industry.

The unregulated and unscrupulous medical hydration spa industry

www.medscape.com/viewarticle/... with @fperrywilson.bsky.social

great HTN JC discussion today on BAXHTN study by Dr. Shawna Nesbitt joined by @dramitkhera.bsky.social @giaconajohn.bsky.social @utswim.bsky.social Interesting that baseline aldosterone in the trial was around 7.5 ng/dL by LCMS with baseline PRA is 1 ng/mlhr. This means that majority of pts have PA

Thank you 🙏

🏆 First time at Epic Cosmos Datathon—our team took 1st place! Grateful for the collaboration and hands on experience ! @drwanpen.bsky.social Excited to present tomorrow (Oct 3) at Pegasus Park Symposium on “Missed Opportunities: Screening for Primary Aldosteronism” #EpicCosmos #HTN

Optimal Treatment of Primary Aldosteronism: Can We Compare Apples to Oranges? Primary aldosteronism (PA) is an endocrine disorder characterized by inappropriate and excessive aldosterone production.1 PA is a prevalent cause of elevat

Comparing Management strategies for Primary Aldosteronism: Is it 🍎 versus 🍊 ?

Commentary academic.oup.com/ajh/article-...

based on
academic.oup.com/ajh/article-...

#Hypertension #Aldosteronism

Reduction of Antihypertensive Treatment in Nursing Home Residents | NEJM Among older adults with frailty, evidence on the benefits and risks of discontinuing antihypertensive drugs is limited. In a multicenter, randomized, controlled trial conducted in France, we assign...

Enough is enough:

RETREAT-FRAIL www.nejm.org/doi/full/10....

OPTIMISE
www.thelancet.com/journals/lan...

DANTON
academic.oup.com/ageing/artic...

No mortality benefit (and potentially harm) from antihypertensive deprescription among frail older adults. Meta-analyze that!

Such a great opportunity, to be involved in an editorial on the most recent evidence for Subclinical Primary Aldosteronism. Thank you to @drwanpen.bsky.social @giaconajohn.bsky.social

Go check it out!! www.ahajournals.org/doi/10.1161/...

Not great Apple, not great
www.accessdata.fda.gov/cdrh_docs/pd...

Our new study that links high Phosphate diet found in processed food and anxiety behavior and alternation of genes involved in mood regulation in mice. That may explain why we don't feel good after a whopper or a big Mac @hkkimphd.bsky.social @utswim.bsky.social sciencedirect.com/science/arti...

My quote of the day

There is a magnet in your heart that will attract true friends. That magnet is unselfishness, thinking of others first; when you learn to live for others, they will live for you.

Paramahansa Yogananda

Some information (still not primary data, more like marketing speak) about the Apple Hypertension detection.

>2,000 adults wore the watch ~12 hours/day for a month and took BID cuff BP; The watch was “as accurate as the cuff” for detecting signs of HTN what ever that is

time.com/7316725/appl...

great HTN journal club discussing GWAS in primary aldosteronism by @jdmosley-moses.bsky.social @giaconajohn.bsky.social www.ahajournals.org/doi/10.1161/...

Inspiring talk by Dr Tom Frieden former director of CDC on the challenges in implementing public health policy emphasizing “Simplification is the ultimate sophistication” and humility in communication to key to success @utswim.bsky.social

Try to find a good reference that describe incidence of impotency related to spironolactone and stumble into this classic article from 1972 by Dr. Carey&Liddle. 3/24 men (12.5%) with low renin HTN had impotency with 400mg/d of aldactone 6wks. pubmed.ncbi.nlm.nih.gov/5082464/
@hswapnil.medsky.social

Remember all the cardiologists whining about Atrial fibrillation with the Apple Watch?

I am sure it has lead to many unnecessary referrals - but also possibly some saves. Surely they didn’t have tsunami of inappropriate referrals right?

Prevalence and Frequency of Self-measured Blood Pressure Monitoring in US Adults This survey study investigates the prevalence, frequency, and factors associated with self-measured blood pressure monitoring among adults ages 50 to 80 years.

But it may still be useful as < 50% of adults age 50-80 monitor home BP regularly and only 62% were recommended by their PCP to check BP . This may be another reason for consumers to check BP with other devices jamanetwork.com/journals/jam...