Franz Meitinger

The mitotic stopwatch synergizes with mild p53 activation to halt cell proliferation https://www.biorxiv.org/content/10.64898/2025.12.02.691971v1

If you’re interested in aneuploidy, mark your calendar! The FASEB SRC on the Consequences of Aneuploidy will be held Sept 28 - Oct 1, 2026 in Melbourne, Florida. Many speaking slots are reserved for early-career researchers. Please help spread the word!

events.faseb.org/event/Aneupl...

Join us for the #CellDivision2026 meeting in Okinawa. Abstract Submission Deadline: Nov 3. www.oist.jp/conference/c...

Join us for the Cell Division Meeting in the Pacific Island setting of Okinawa.
Hosted at OIST, this symposium brings together leading researchers to explore emerging roles of the cell cycle in development, cancer, and aging.

Registration now open: www.oist.jp/conference/c...

Special Application Deadline for Students Accepted or Studying in the United States

The OIST Graduate School has opened a Special PhD Admissions Portal for students currently enrolled in, or accepted to, universities in the U.S. #PhDprogram

www.oist.jp/admissions/s...

Thank you 😊

Excited to share our new preprint on @biorxivpreprint!
We show that USP28 mutations found in cancer block its interaction with 53BP1, disrupting p53 stabilization. Check out the full story... @Midori_RuruOta
www.biorxiv.org/content/10.1...

PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential Centrosomes catalyze the assembly of a microtubule-based bipolar spindle, essential for the precise chromosome segregation during cell division. At the center of this process lies Polo-Like Kinase 4 ...

Check out our review on "PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential".

Everything you need to know about centriole duplication, mitotic stopwatch and TRIM37-mediated cancer-specific vulnerabilities.

onlinelibrary.wiley.com/doi/10.1002/...

Our base editor plasmids are now available on addgene: www.addgene.org/Franz_Meitin...

We wish you Happy Holidays from Okinawa!

A prolonged mitosis is characteristic of defects that drive genome instability. What are the underlying causes and broader implications of prolonged mitosis? Check out our review...

authors.elsevier.com/sd/article/S...

Genetic Engineering and Screening Using Base Editing and Inducible Gene Knockout Genetic engineering and screening in human cells are powerful techniques for the precise and comprehensive identification and analysis of gene and protein domain functions. Genome-wide knockout screen...

Interested in Base Editing and Genetic Screening?
Check out our method chapter: link.springer.com/protocol/10....
Esther Ng did an excellent job developing these methods in our lab. The constructs will soon be available on @addgene.bsky.social
Many thanks to OIST for supporting open access!

@MBSJ 2024 in Fukuoka