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Raff Lab

@jrafflab.bsky.social

Interested in how centriole and centrsomes build themselves

473 Followers  |  300 Following  |  3 Posts  |  Joined: 07.11.2024  |  1.4787

Latest posts by jrafflab.bsky.social on Bluesky

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β€ͺ
Many congratulations to all our postdocs recently awarded postdoctoral fellowships! πŸ₯³

A special mention to @carokobras.bsky.social for a BBSRC Fellowship, and Emma and Laura for @wellcometrust.bsky.social early career awards!

Check the full list here: www.path.ox.ac.uk/news-article...

17.04.2025 21:13 β€” πŸ‘ 17    πŸ” 2    πŸ’¬ 0    πŸ“Œ 2
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The conserved Spd-2/CEP192 domain adopts a unique protein fold to promote centrosome scaffold assembly A conserved structural domain within CEP192/Spd-2 protein promotes centrosome scaffold assembly during centrosome maturation.

πŸ”¬ Exciting findings from our collaborative study with Lea, Raff, van Breugel&Feng Lab! We've uncovered how Spd-2/CEP192 proteins with an SP2D structure are crucial for centrosome assembly. Crystal structures&mutations reveal new insights into PCM scaffold formation.

www.science.org/doi/10.1126/...

30.03.2025 04:28 β€” πŸ‘ 15    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
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#biologists100
Please come to my poster on Wed at the Liverpool conference and see how the @jrafflab.bsky.social with @dunngogreen.bsky.social @dunnschool.bsky.social is conducting our world class science in an environment friendly way at @ox.ac.uk ! Saving money & planet! There is no planet B!

24.03.2025 16:30 β€” πŸ‘ 19    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
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Centrioles generate two scaffolds with distinct biophysical properties to build mitotic centrosomes Spd-2 organizes the assembly of two distinct centriole-scaffolds to build mitotic centrosomes in Drosophila.

πŸ”¬ Excited to share our latest paper! We’ve found how Spd-2 coordinates with Polo and Aurora A to build critical scaffolds in centrosome assembly in Drosophila. 🧬 www.science.org/doi/10.1126/...

10.02.2025 06:45 β€” πŸ‘ 20    πŸ” 10    πŸ’¬ 0    πŸ“Œ 2

Happy to be here. Hopefully this will be fun and useful. Like Twitter used to be.

19.11.2024 08:33 β€” πŸ‘ 9    πŸ” 0    πŸ’¬ 1    πŸ“Œ 1

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