A comprehensive genetic catalog of human double-strand break repair | Science www.science.org/doi/10.1126/...
02.10.2025 18:47 β π 24 π 9 π¬ 1 π 0@altmeyerlab.bsky.social
Genome integrity maintenance during cell cycle progression: This is what we care about, this is what we study. #GenomeStability #ReplicationStress #DNADamage #UZH #Science #AcademicSky https://www.altmeyerlab.org/
A comprehensive genetic catalog of human double-strand break repair | Science www.science.org/doi/10.1126/...
02.10.2025 18:47 β π 24 π 9 π¬ 1 π 0A screenshot of a post by the Jane Goodall Institute on LinkedIn stating that they learned that Dr. Goodall passed away due to natural causes in California while on her speaking to her current speaking tour there.
The world has lost its most powerful advocate for nature and hope. Yet many remain who will continue her legacy and I know she will continue to inspire generations more.
01.10.2025 18:01 β π 1607 π 476 π¬ 37 π 63Come and join us at the Barts Cancer Institute @qmbci.bsky.social ! Our medical school, part of Queen Mary University of London @qmulfmd.bsky.social is hiring 10 professors!! www.veredus.co.uk/job/job-747a/. Contact me for a chat if interested.
01.10.2025 07:34 β π 19 π 9 π¬ 1 π 1Thrilled that our work is now finally out in Nature Comms!
rdcu.be/eG3vP
We reveal cryo-EM structures of the MRN complex bound to DNA & TRF2 - showing how DNA breaks are sensed and regulated at telomeres.
Fantastic work by first authors @yilanfan.bsky.social @filizkuybu.bsky.social & Hengjun!
Congratulations to Dirk GΓΆrlich and Steven L. McKnight, 2025 #LaskerAward winners! - βfor discoveries that exposed the structures and functions of low-complexity domains within protein sequencesβ π§ͺ
@mpi-nat.bsky.social
#Lasker2025 #LaskerLaureate #structuralbiology #phaseseparation
My first post on bsky to share our latest research in @nature.com: βDNA2 enables growth by restricting recombination-restarted replicationβ - defines DNA2βs essential function & elucidates links with primordial dwarfism and cancer. Thanks to the lab, collaborators & @ukri.org @acmedsci.bsky.social
03.09.2025 15:59 β π 39 π 19 π¬ 7 π 1π’Deadline extended!
Our 2nd Spatial Genome Organisation Conference deadline has been extended to 25 Sep, dont miss out on joining our fantastic line up of speakers, alongside Karim, Matthias and Irene in what is set to be a fantastic meeting this October! #SGO25
Final slots β‘οΈhttps://bit.ly/3JJzYR4
@efapostolou29.bsky.social @thecesarelab.bsky.social we're looking forward to your presentations at this fantastic meeting!
02.09.2025 14:35 β π 2 π 1 π¬ 0 π 0Image of Toronto
JOB ALERT π¨ We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto.
www.nature.com/naturecareer...
Please repost!
Deadline approaching for #SGO25
π 31 Oct β 03 Nov 2025
πRiviera Maya, Mexico
Poster & Reg deadline: 01 Sept 2025
Details & Reg: bit.ly/45Mmhtv
$250 registration grants available! Email amy@fusion-conferences.com with your name, position & current research topic.
Advertisements for 2 tenure-track assistant professor positions at Vanderbilt School of Medicine Basic Sciences:
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Another exciting research article from a member of the #RepliFate network!
The Altmeyer lab identified the CNOT1-CCR4-NOT complex as a multi-level suppressor of the 53BP1-p53-p21 signaling axis.
Check out their findings here: doi.org/10.1016/j.ce...
New work from the lab: Identification of CNOT1-CCR4-NOT as a suppressor of 53BP1-p53-p21 signaling @cp-cellreports.bsky.social. Congratulations to first author Antonio Galarreta and to all co-authors. www.cell.com/cell-reports.... #Microscopy #RNAiScreen #Condensates
31.07.2025 14:09 β π 4 π 2 π¬ 0 π 0Our new non-denaturing nanoscale 3D DNA tracing technology provides single-cell (and sister-chromatid specific!) readout of chromatin structure with 10kb genomic resolution - Check it out!
www.nature.com/articles/s41...
Congratulations to Kai and Oyvind!!
π£ We are recruiting new group leaders in Innovative Biology!
RNA biology
Epigenetic regulation
Cell cycle regulation
Cancer, immunology
Virology
Application and information β¬οΈ
application.igmm.cnrs.fr
@cnrsbiologie.bsky.social @cnrsoccitanieest.bsky.social @umontpellier.bsky.social
New @nature.com
An ingenious way to track DNA replication patterns at the single-cell level that leads to cell heterogeneity and daughter cells that can potentially give rise to cancer
www.nature.com/articles/s41...
π¬Under the microscope: DNA damage tracked through cell generationsπ¬
It was a pleasure to write this #NewsAndViews with our PhD student Emma Reilly, online today @nature.com
rdcu.be/em0qi
@cruk-ci.bsky.social @spjacksongroup.bsky.social @yalepathology.bsky.social @yalecancer.bsky.social
Sharing our latest work tracking DNA damage inheritance by Live+QIBC www.nature.com/articles/s41.... Huge congrats to @apanagopoulos.bsky.social, M. Stout and all co-authors for this tour de force! Beautifully summarized by @s-j-aitken.bsky.social & E. Reilly www.nature.com/articles/d41...
21.05.2025 15:57 β π 43 π 11 π¬ 0 π 3Looking very much forward to the 2nd edition of the Fusion Conference on Spatial Genome Organisation #SGO25 @fusionconf.bsky.social @karimmekhail.bsky.social @chiololab.bsky.social. Early bird registration closes soon: June 2nd, 2025. Slots available for selected talks from abstracts: bit.ly/4492G6i
15.05.2025 12:25 β π 2 π 3 π¬ 0 π 0IMBA is recruiting a Junior Group Leader! Are you interested in starting your own lab, pursuing curiosity-driven basic research in the life sciences? Apply by May 18: imba.science/beagroupleader #hiring #biology #research #groupleader #europe
14.05.2025 07:00 β π 15 π 19 π¬ 0 π 1Poster with DGZ 2025 Meeting details (speakers list, organizers, sponsors)
We are excited to announce the details for this yearβs #DGZ International Meeting, a very special one as we are celebrating 50 years of DGZ! Join us in October in Heidelberg, where the DGZ was founded in 1975. Check the speakers line-up etc. at the poster. Registration: shorturl.at/EHUzb #DGZ50
08.04.2025 10:51 β π 28 π 14 π¬ 1 π 5Weβre excited to share our work where we investigated the mechanisms of chromosome motion by tracking all #chromosomes, mapping their interactions, and live cell karyotyping, using #AI based denoising, segmentation and registration, published in Nature Cell Biology.
www.nature.com/articles/s41...
Interested in these or related topics and looking for (or know somebody looking for) a PhD position? We have openings and an approaching application deadline @lifesciencezurich.bsky.social: www.lifescience-graduateschool.uzh.ch/en.html. Please repost. #PhDLife #LifeScience #Switzerland
27.03.2025 15:13 β π 3 π 2 π¬ 0 π 01/10 Excited to share our latest - the first whole-body map of both DNA methylation and 3D genome at single-cell resolution.
25.03.2025 15:49 β π 8 π 5 π¬ 1 π 1Our new findings on how chromosomes get ready for cell division are now published in @cellpress.bsky.social!
Congratulations, Kai, @andibrunner.bsky.social and everyone else involved! π€©
www.sciencedirect.com/science/arti...
Come start your lab in beautiful Strasbourg π«π· www.nature.com/naturecareer...
22.03.2025 13:50 β π 35 π 29 π¬ 1 π 0Thrilled to share our lab's first preprint, led by an exceptional PhD student Gita Chhetri and with the support of wonderful collaborators, we find that replisome function is rate-limited by strand-specific PCNA dynamics. Hope you will enjoy reading.
www.biorxiv.org/content/10.1...
Brief teaser:
How are chromosome breaks repaired and how is their repair influenced and facilitated by nuclear and genome dynamics? Fantastic initiative and collaboration with @karimmekhail.bsky.social, @chiololab.bsky.social, and @lablegube.bsky.social. @natrevmcb.bsky.social Link to article: rdcu.be/edViW
18.03.2025 16:32 β π 67 π 22 π¬ 1 π 1I put together a small guide on how to get started with Fiji. Please distribute to anyone who might benefit form this! zenodo.org/records/1477... #imageanalysis #fiji #imagej #training
30.01.2025 15:10 β π 165 π 62 π¬ 5 π 0We have an exciting opportunity for a new independent group leader with an interest in structural/molecular biology and machine learning to join our Division of Structural Studies at the @mrclmb.bsky.social! π₯³
Re-posts appreciated.
www.nature.com/naturecareer...