@mtleelab.bsky.social
Assoc Professor, Pitt BioSci. Eggs + gene regulation. Fish, frogs, cnidarians, ...
In situ of a zebrafish embryo looking like a platypus
A platypus (image source: NYT)
05.12.2024 13:56 — 👍 3 🔁 0 💬 0 📌 0One thing we do in our review is just provide a source for references to many other reviews on individual topics, collect many refs for recent structural work, and also try to point to some older key papers. We also try to emphasize open questions or where interpretation can be tricky
27.11.2024 18:58 — 👍 17 🔁 4 💬 1 📌 0
Graphical abstract of the study
Out now in Dev Cell! scRNAseq trajectories describe the cascade of gene expression as cells differentiate, but turning them into a clear understanding of the underlying biology of a cell type's development remains challenging. authors.elsevier.com/c/1k9qj5Sx5g... (1/)
26.11.2024 15:49 — 👍 159 🔁 50 💬 14 📌 3Calling all systems and computational biologists in search of a faculty position:
We have Assistant and Associate Professor positions! 🚀
Pittsburgh is beautiful, and we are doing amazing science here.
cfopitt.taleo.net/careersectio...
cfopitt.taleo.net/careersectio...
Please apply by Dec 2!
PhD position(s) available in #development #genomics: tinyurl.com/9dk9m29d
European (#MSCA) doctoral training network, #DanioreCODE (tinyurl.com/2rz4mdsa).
How does #transcription initiation regulation control #brain injury response and #regeneration in #zebrafish?
Congratulations to all who shared their science at #ABRCMS2024 , especially all of our amazing and accomplished Pitt students! So honored to get to work with all of you!
18.11.2024 02:32 — 👍 3 🔁 0 💬 0 📌 0If you are going to #ABRCMS2024 in Pittsburgh stop by the NSF Bio Booth! We'll have tons of info for anyone interested in applying to NSF... that includes all you faculty in attendance! We're also doing an NSF101 professional development session today (11/13) from 5:15-6pm in CC401-402.
13.11.2024 13:49 — 👍 4 🔁 1 💬 0 📌 0
Graphic showing the pro-inflammatory caspase locus in human and mouse genomes. In human, there have been many, recent duplications of caspase genes, shown in colored arcs (panel A) as well as non-coding regions (panel B). In mouse there is essentially no recent innovation in the locus, other than some transposons moving around.
New paper from the lab now published in MBE:
Evolutionary dynamics of pro-inflammatory caspases in primates and rodents! We found some cool stuff about how these immune proteins rapidly evolve, with implications for functional studies 1/n
academic.oup.com/mbe/advance-...
3D micrograph of the developing D. eugracilis terminalia
Our new @CurrentBiology paper provides a rare glimpse into a morphological novelty in Drosophila eugracilis
In it, @gavinrrice and colleagues, infer and reproduce the likely initial steps of a novelty's formation
www.sciencedirect.com/science/arti...
