American Journal of Hypertension

Volume 38 Issue 11 | American Journal of Hypertension | Oxford Academic Publishes research in basic sciences, molecular biology, clinical and experimental hypertension, cardiology, epidemiology, pediatric hypertension, endocrinology, neurophysiology, and nephrology.

The November issue is online!

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Reviews, commentaries and lots of original reasearch!

Pro-neurotensin/Neuromedin N and Hypertension Risk: A Prospective Study AbstractBackground. Neurotensin, a neuropeptide with direct cardiac effects, has been associated with prospective risk of hypertension-related conditions t

#WeekendReads from the Archives

Pro-neurotensin/Neuromedin N and Hypertension Risk: A Prospective Study

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Development and Pilot Testing of Hypertension Management Support With EHR-Integrated Telemonitoring and Proactive Patient Messaging AbstractBACKGROUND. Automated patient messages based on home blood pressure (BP) may help overcome clinician and patient inertia in hypertension treatment.

#WeekendReads from the #AdvanceArticles section

Hypertension Management Support With EHR-Integrated Telemonitoring and Proactive Patient Messaging

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#OpenAccess

Racial and Gender Discrimination When Tailoring Medical Management to Hypertension Treatment in Latin America: As a Key Player in the field, the Inter-American Society of Hypertension advocates equitable healthcare approaches in Latin America Abstract. Discrimination in cardiovascular healthcare, particularly concerning hypertension treatment, is a significant and complex issue in Latin America,

Racial and Gender Discrimination When Tailoring Medical Management to Hypertension Treatment in Latin America: As a Key Player in the field, the Inter-American Society of Hypertension advocates equitable healthcare approaches in Latin America

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Defining Systolic Blood Pressure Variability in Home Monitoring: Time for Standardization In the current issue of the American Journal of Hypertension, Zhang and colleagues report that higher levels of mean systolic blood pressure (SBP) and seve

Defining Systolic Blood Pressure Variability in Home Monitoring: Time for Standardization

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Original Article academic.oup.com/ajh/article/...

Integrating Proteomics and Mendelian Randomization to Identify New Therapeutic Targets Hypertension is a major risk factor for cardiovascular disease, stroke, renal failure, and other end-organ damage. It is estimated that over 1.4 billion pe

Integrating Proteomics and Mendelian Randomization to Identify New Therapeutic Targets

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Original Article: academic.oup.com/ajh/article-...

Salt-Induced Vascular Damage in Hypertension Involves Redox Activation of PARP/TRPM2 Signaling and Inflammasome Assembly AbstractBACKGROUND. Excess sodium intake induces vascular dysfunction. Molecular mechanisms underlying this are unclear. Here we investigated the role of r

Salt-Induced Vascular Damage in Hypertension Involves Redox Activation of PARP/TRPM2 Signaling and Inflammasome Assembly

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#EditorsChoice #Free

Association of Arterial Stiffness With Kidney Function Among Adults Without Chronic Kidney Disease AbstractBACKGROUND. Our aims were to assess whether arterial stiffness is associated with a higher risk for kidney dysfunction among persons without chroni

Association of Arterial Stiffness With Kidney Function Among Adults Without Chronic Kidney Disease

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#WeekendRead from the #EditorsChoice

Hypertension in Thoracic Aortic Dissection: A Meta-Analysis-Based Considerations in the Choice of Antihypertensive Agents AbstractBACKGROUND. Thoracic aortic dissection (TAD) is a potentially fatal condition. It has been linked with hypertension, and guidelines recommend antih

Which antihypertensive agents should be used in Thoracic Aorta Dissection?

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#WeekendReads from the Advance Articles section

Vascular Stiffness, Instead of Coronary Artery Calcification, Exhibits Significant Association With Hypertension Risk in General Population AbstractBACKGROUND. Hypertension (HTN) significantly increases cardiovascular risk worldwide, and its incidence is expected to rise further over time. Both

ascular Stiffness, Instead of Coronary Artery Calcification, Exhibits Significant Association With Hypertension Risk in General Population

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Home Blood Pressure Monitoring Among Adolescents and Young Adults, NHANES 2009–2014 AbstractBACKGROUND. Among middle-aged and older adults, home blood pressure (BP) monitoring (HBPM) is a tool for both diagnosis and management of hypertens

Home Blood Pressure Monitoring Among Adolescents and Young Adults, NHANES 2009–2014

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#Free #OpenAccess

Association of Anxiety with Discrepancies Between Unattended and Attended Office Blood Pressure Measurement AbstractBACKGROUND. Precision of blood pressure (BP) measurements is crucial in hypertension care. Conventional office measurements (OBP) are susceptible t

Association of Anxiety with Discrepancies Between Unattended and Attended Office Blood Pressure Measurement

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Plasma Reactive Dicarbonyls Are Not Independently Associated With Arterial Stiffness: The Maastricht Study AbstractBACKGROUND. Arterial stiffness is a strong predictor of cardiovascular diseases and all-cause mortality. Increased concentrations of highly reactiv

Plasma Reactive Dicarbonyls Are Not Independently Associated With Arterial Stiffness: The Maastricht Study

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#OpenAccess #Free

Stenotic Lesions of the Intracranial Arteries in Relation to the Average Level and Variability of the Home Blood Pressure: A Cross-Sectional Study AbstractBACKGROUND. This study assessed the presence of intracranial arterial stenosis (ICAS) in relation to home systolic blood pressure (SBP) and its var

Stenotic Lesions of the Intracranial Arteries in Relation to the Average Level and Variability of the Home Blood Pressure: A Cross-Sectional Study

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#OpenAccess #Free

The Association Between Diabetes and Hypertension Time Course, Their Cumulative CoExposure, and PostCoronary Artery Bypass Graft Outcomes AbstractBACKGROUND. The association between patient outcomes and cumulative effects of cardiovascular risk factors over time is recognized but poorly quant

Vascular Stiffness, Instead of Coronary Artery Calcification, Exhibits Significant Association With Hypertension Risk in General Population

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The Association Between Diabetes and Hypertension Time Course, Their Cumulative CoExposure, and PostCoronary Artery Bypass Graft Outcomes AbstractBACKGROUND. The association between patient outcomes and cumulative effects of cardiovascular risk factors over time is recognized but poorly quant

The Association Between Diabetes and Hypertension Time Course, Their Cumulative CoExposure, and PostCoronary Artery Bypass Graft Outcomes

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Association Between Estimated Daily Salt Intake from Spot Urine and Nocturnal Blood Pressure in Hypertensive Patients under Antihypertensive Treatment AbstrcatBackground. Excessive salt intake is a major contributor to hypertension and is associated with elevated nocturnal blood pressure (BP), particularl

Association Between Estimated Daily Salt Intake from Spot Urine and Nocturnal Blood Pressure in Hypertensive Patients under Antihypertensive Treatment

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Adherence to Recommended Laboratory Testing for Hypertension: Insights from a Nationwide Cohort AbstractBACKGROUND. Despite guideline recommendations, the prevalence of laboratory testing among patients newly diagnosed with hypertension (HTN) in the U

Adherence to Recommended Laboratory Testing for #Hypertension: Insights from a Nationwide Cohort

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State of the Art Review: Thiazide Diuretics Exploit the Endocannabinoid System via NAPE-PLD Abstract. The present State of the Art Review will take stock of targeting the endocannabinoid system (ECS) in the management of hypertension and vascular

The endocannabinoid system as a target for thiazide diuretics?

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#WeekendReads from the #AdvanceArticles section

Blood Pressure Outcomes Following a Home Blood Pressure Monitoring Program in a Large Integrated US Health System AbstractBackground. Home blood pressure telemonitoring (HBPT) can empower patients to participate in their healthcare and reduce office BP. Evidence that B

Blood Pressure Outcomes Following a Home Blood Pressure Monitoring Program in a Large Integrated US Health System

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#EditorsChoice #Free

Two-Day ABPM-Derived Indices and Mortality in Hemodialysis Patients AbstractBACKGROUND. Blood pressure (BP) and arterial stiffness are known cardiovascular risk factors in hemodialysis (HD) patients. This study examines the

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Two-Day ABPM-Derived Indices and Mortality in Hemodialysis Patients

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Potential Therapeutic Drug Targets for Hypertension Identified Using Proteomics and Mendelian Randomization AbstractBACKGROUND. Hypertension (HT) is the most prevalent risk factor for cardiovascular disease (CVD) worldwide. Despite being a highly heritable trait,

Potential Therapeutic Drug Targets for Hypertension Identified Using Proteomics and Mendelian Randomization

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Exploring the Causal Relationships Between Anxiety, Obesity, and Hypertension: A Two-Sample Mendelian Randomization Study AbstractBACKGROUND. Both anxiety and obesity have been implicated in hypertension development, with emerging evidence suggesting metabolic risk factors as

A Causal Relationships Between Anxiety, Obesity, and Hypertension? A Mendelian Randomization study

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Reserpine Substantially Lowers Blood Pressure in Patients With Refractory Hypertension: A Proof-of-Concept Study AbstractBACKGROUND. Refractory hypertension (RfHTN), a phenotype of antihypertensive treatment failure, is defined as uncontrolled automated office blood p

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Does Reserpine deserve a Relook for Resistant Hypertension?

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Is It Time to Retire Aldosterone Suppression Testing? Abstract. Primary aldosteronism (PA) is the most common endocrine hypertension. For decades, PA diagnosis has required proving nonsuppressibility of aldost

#WeekendReads from the Advance Articles section

Time to retire Aldosterone Suppression Testing?

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Commentary on “Plasmacytoid Dendritic Cell Content Is Associated With Plasma Aldosterone Concentration in Patients With Primary Aldosteronism” Primary aldosteronism (PA) is a leading cause of secondary hypertension, characterized by autonomous aldosterone excess, which drives sodium retention, vol

Commentary on 'Plasmacytoid Dendritic Cell Content Is Associated With Plasma Aldosterone Concentration in Patients With Primary Aldosteronism'

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based on
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Glomeruli and Blood Pressure: Less of One, More the Other? Abstract. A primary role for the kidney in the initiation and maintenance of hypertension has long been recognized, but the pathogenetic interactions among

#ThrowbackThursday

Glomeruli and Blood Pressure: Less of One, More of the Other?

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from Brenner, Garcia and Anderson, 1988

Optimal Treatment of Primary Aldosteronism: Can We Compare Apples to Oranges? Primary aldosteronism (PA) is an endocrine disorder characterized by inappropriate and excessive aldosterone production.1 PA is a prevalent cause of elevat

Comparing Management strategies for Primary Aldosteronism: Is it 🍎 versus 🍊 ?

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based on
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#Hypertension #Aldosteronism

Recent Advances in Adrenal Ablation for Primary Aldosteronism Primary aldosteronism (PA) is characterized by autonomous renin-independent aldosterone production from one or both adrenal glands which leads to inappropr

Advances in Adrenal Ablation for Aldosteronism

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Based on
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and
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#Aldosteronism #Hypertension

Volume 38 Issue 10 | American Journal of Hypertension | Oxford Academic Publishes research in basic sciences, molecular biology, clinical and experimental hypertension, cardiology, epidemiology, pediatric hypertension, endocrinology, neurophysiology, and nephrology.

The October issue is online

academic.oup.com/ajh/issue/38...

Salt, stiffness, home BP and much more

#Hypertension