Jen Li

YouTube video by Prof. Jean Fan RNA velocity in situ infers gene expression dynamics using spatial transcriptomics data

What is RNA velocity in situ? ChatGPT kept getting it wrong...

So I made this video explaining how RNA velocity in situ infers gene expression dynamics by distinguishing nuclear vs. cytoplasmic expression in spatial transcriptomics data: youtu.be/z9Oxf1hvum0

#AcademicSky

Actionable genes in CKD ca. 2024 from @kdigo.org
#RKDSummit #Nephpearls #NephSky

👉 kdigo.org/guidelines/c...

Changing paradigms of studies in kidney diseases

doi.org/10.1016/j.kint.2025.09.016

#OpenAccess #NephSky #MedSky #kidneydisease #CKD
@sydney.edu.au @uofglasgow.bsky.social @fbmh-uom.bsky.social @ucl.ac.uk @livuni-ilcams.bsky.social @flindersuniversity.bsky.social @theisn.org

Scaling up spatial transcriptomics for large-sized tissues: uncovering cellular-level tissue architecture beyond conventional platforms with iSCALE - Nature Methods iSCALE leverages histology and spatial transcriptomics to infer gene expression at super resolution in large tissues.

iSCALE

www.nature.com/articles/s41...

Review: The relationship between genetic mutations and formation of specific amyloid fibril structures drives inheritance patterns of amyloid diseases
www.science.org/doi/10.1126/...

OBAMA: It's fair to say that 80% of the world's problems involve old men hanging on who are afraid of death and insignificance, and they won't let go. They build pyramids, and they put their names on everything. They get very anxious about it.

New in Transplantation! Patient Selection for Xenotransplant Human Clinical Trials: A Data-driven Approach. #TXPforAll #Transplantation tinyurl.com/4fwsv44c

Is that a sclerosed glom in the water?

👏 Congratulations to Katalin Susztak, MD, PhD, recipient of the 2026 David M. Hume Memorial Award!

Learn more ➡️ bit.ly/47Taye5

We look forward to celebrating our award winners at SCM26 #NKFClinicals. Stay tuned for registration opening October 2025.

@ksusztak.bsky.social

Personalising Immunosuppression:Is Tacrolimus C/D Ratio the New frontier in predicting allograft outcomes Written by  Priyadarshini John DMReviewed by Sophia Ambruso, DOKidney transplantation remains the most effective form of treatment for end-stage renal disease, with a substantial improvement in patien...

🚨Check out the latest KI Reports community blog on the personalization of immunosuppression from @drpriyajohn.bsky.social
#NephSky

www.kireportscommunity.org/post/persona...

Now open access in @NDTsocial

Anti-GBM disease - Treatment Standard

🧐 Anti-GBM and ANCA positive pts have a higher relapse risk and require maintenance immunosuppressive treatment

▶️ academic.oup.com/ndt/article/...

KDIGO is pleased to announce the publication of the 2025 IgA Nephropathy (#IgAN) and IgA Vasculitis (#IgAV) Guideline, along with its Executive Summary in @kidneyint.bsky.social.

Download: kdigo.co/KDIGO-IgAN-I...

Read in KI: kdigo.co/KDIGO-IgAN-I...

Exec Summary: kdigo.co/IgAN-IgAV-Gu...

Don't miss the latest Behind the Paper with David K.C. Cooper!
Watch or listen to an in-depth interview on the recent @transplantation.bsky.social paper 👉 The Relative Roles of Inflammation in Kidney Allotransplantation and Xenotransplantation

🔗 tinyurl.com/mr47jdzk

Extracorporeal photopheresis shows promise in reducing donor-specific antibodies and improving long-term transplant survival. #TXPforAll #OpenAccess #Transplantation tinyurl.com/md9b2h3w

Adoptive transfer of NK cells engineered with a CD5-based chimeric antigen receptor (SRCD5CAR) to treat invasive fungal infections @moltherapy.bsky.social
@idibaps.bsky.social
www.cell.com/molecular-th...

Excited to share our publication in Kidney International Reports with thanks to @georginairish.bsky.social @philclayton.bsky.social

@tregaustralia.bsky.social

doi.org/10.1016/j.ek...

🤩🎉 well deserved @georginairish.bsky.social - onwards to more great work and contributions to the transplant field

Important to consider recipient DM status if we accept diabetic kidneys for transplantation

I recall studying the complement system as part of med school, physician training and PhD, yet there's still so much to learn to understand how this can impact health and clinical care. #understandfundamentals #internationalcomplementworkshop #icw2025

We need to do better, esp for PD patients

Making the most of September's opportunities 🙏
- Biomarkers in KTx #ANZSN2025
- MGRS/malignancy in glom disease #ANZGlomerularDiseaseWorkshop
- virtually tune in for the Mayo Onconeph Symposium

Ready to absorb complement knowledge with Int Complement Congress tmr 😬 before back to the daily grind

Nephrotic syndrome doesn’t just cause swelling; it can lead to infections, blood clots, kidney damage, and many other complications. 💧🩸🦠

📌 Learn more about our research and how you can support families affected by kidney disease at the link in our bio. #nephrology #genomics

Interesting, What's the mechanism for protection? Through anti-inflam effects of 1,25-vit D on mononuclear cells?

Sign up for the upcoming webinar (next week!) to learn about the impact of SOT in HCT recipients and vice versa @ttsorg.bsky.social @transplantation.bsky.social
#TTSEducation

tts.org/join-tts/116...

A timely SR and meta analysis highlighting the likely benefits of SGLT2i and GLP1ra in transplantation. @ttsorg.bsky.social @transplantation.bsky.social

LIsten to Leo Riella give an excellent summary - TTS pulse podcast on Spotify with @drmaceylevan.bsky.social

open.spotify.com/show/0srDXx3...

Check out the latest from @transplantation.bsky.social @ttsorg.bsky.social @drmaceylevan.bsky.social

tts.org/index.php?op...

🌍 Applications open! The Transplantation Editorial Fellowship welcomes early-career researchers, clinicians & post-docs ready to shape the future of transplant science & publishing. 📖. #Transplantation #TXPforAll journals.lww.com/transplantjo...

Genetic sex is an important determinant of kidney injury and repair, with female kidneys typically exhibiting greater resilience to AKI. This #ASNJASN research examines how augmenting Gsta2 expression in male proximal tubule cells affects resistance to IRI. kidney.pub/JASN0840