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@ada-w-yan.bsky.social

74 Followers  |  300 Following  |  13 Posts  |  Joined: 24.09.2024  |  2.0943

Latest posts by ada-w-yan.bsky.social on Bluesky

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Modelling the dynamics of SARS-CoV-2 during the first 14 days of infection Interpreting the viral mechanism of SARS-CoV-2 based on the human body level is critical for developing more efficient interventions. Due to the limit…

New paper! "Modelling the dynamics of SARS-CoV-2 during the first 14 days of infection" - we use Approximate Bayesian Computation and the theory of stochastic boundary hitting to provide a possible explanation for infectious doses in challenge data.

www.sciencedirect.com/science/arti...

22.07.2025 21:58 β€” πŸ‘ 38    πŸ” 13    πŸ’¬ 2    πŸ“Œ 0

Assuming that the aim of group brainstorming is idea generation and information transfer -- more often I've found that group brainstorming is just a vehicle for participants to chat on a technical topic and get to know each other's expertise?

30.07.2025 00:31 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Job Details

We're hiring a modelling postdoc at PSI Oxford for two exciting projects: 1) modelling the early immune responses to Nipah vaccination, and 2) joining the PRESTO team working on immunobridging in vaccine evaluation studies.

tinyurl.com/5abbxrjh

Get in touch for more info! Deadline 4th August.

11.07.2025 11:32 β€” πŸ‘ 12    πŸ” 11    πŸ’¬ 0    πŸ“Œ 2

I think if I've done my fair share that's enough, I have no obligation to compensate for freeloaders (and certainly not to the extent of assuming all my co-authors will be freeloaders).

08.07.2025 03:59 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Tracking West Nile virus dynamics using viral loads from trapped mosquitoes West Nile virus (WNV) persists in an enzootic cycle between birds and mosquitoes. Human infections are incidental and usually sub-clinical with some cases of neuroinvasive disease. Mitigation relies on surveillance to guide decision making, including RT-qPCR testing pools of mosquitoes. Cycle threshold (Ct) values from these pools\---|semi-quantitative proxies for viral load\---|are binarised to estimate WNV prevalence in mosquitoes as a proxy for human risk. We showed that Ct value variation in Colorado and Nebraska (2022-2024) cannot be explained by laboratory factors, suggesting a role for biological and epidemiological mechanisms. We developed a multiscale model linking pooled Ct values to mosquito viral kinetics, bird-to-mosquito transmission, and seasonal force of infection. A novel method estimating WNV prevalence using pooled Ct values outperformed existing approaches at high prevalence. We demonstrate the importance of treating environmental viral load samples as quantitative, as binarising masks key information for arbovirus surveillance and risk mitigation. ### Competing Interest Statement The authors have declared no competing interest. Wellcome Trust Early Career Award, grant 225001/Z/22/Z UNMC VCR

New preprint!
We use pooled Ct values from mosquito surveillance to estimate West Nile virus prevalenceβ€”without binarising the data.
Joint work with Ian Marchinton, Joseph R. Fauver & James Hay.
Check it out: www.biorxiv.org/content/10.1...

07.07.2025 08:38 β€” πŸ‘ 11    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1

I do number of submissions * 3 / mean number of co-authors on my submissions. If all my co-authors did number of submissions * 3, then collectively we have far exceeded the reviews required?

08.07.2025 01:22 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Job vacancy: Senior Statistician, UK Health Security Agency, Birmingham | trac.jobs

Please circulate to anyone interested: Senior Statistician role at UK Health Security Agency national Real-time Syndromic Surveillance Team. This would be a great job for any modellers or statisticians with an interest in surveillance.

www.healthjobsuk.com/job/UK/Londo...

07.07.2025 15:04 β€” πŸ‘ 4    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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Avian Influenza A(H5N1) Isolated from Dairy Farm Worker, Michigan, USA Avian Influenza A(H5N1) Isolated from Dairy Farm Worker, Michigan

Important result from CDC research team: H5N1 flu virus from a dairy farm worker transmitted by direct contact in ferrets with 100% efficiency (6/6 animals infected) and by droplets/aerosols in ferrets, physically separated, with 50% efficiency (3/6 animals infected).

wwwnc.cdc.gov/eid/article/...

09.06.2025 18:18 β€” πŸ‘ 82    πŸ” 35    πŸ’¬ 4    πŸ“Œ 4
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Postdoctoral positions in epidemic mathematical/statistical modelling - Research Job description We are recruiting postdocs to contribute to research projects in the Mathematical Modelling of Infectious Diseases Unit, at Institut Pasteur in Paris. The candidates will be expected t...

New postdoc positions with a number of exciting epidemic modelling projects opening in our Unit at @pasteur.fr in beautiful Paris. Deadline for applications: 26th June.
research.pasteur.fr/en/job/postd...

05.06.2025 05:22 β€” πŸ‘ 54    πŸ” 65    πŸ’¬ 0    πŸ“Œ 3
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Description Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

Great opportunity to work on influenza virus-host factor interactions in a brand new lab at Imperial (led by a friend and collaborator, Carol Sheppard)
www.imperial.ac.uk/jobs/search-...

22.05.2025 16:26 β€” πŸ‘ 10    πŸ” 8    πŸ’¬ 0    πŸ“Œ 1
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Research Associate in Mathematical Epidemiology :Manchester

Come and work with us! Postdoctoral research job to look at methods for working with early pandemic "First Few X" datasets in resource-limited contexts. Please consider applying if of interest and circulate around your networks.

www.jobs.manchester.ac.uk/Job/JobDetai...

06.05.2025 14:45 β€” πŸ‘ 21    πŸ” 18    πŸ’¬ 1    πŸ“Œ 1
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Panel Discussion: 'What turns spillovers into epidemics?' This talk brings together experts in pathogen genomics, virology, ecology, climate science, and data science to explore how AI, genomic surveillance, and…

Interesting looking set of talks on 'What turns spillovers into epidemics?' w @jessmetcalf.bsky.social @danielstreicker.bsky.social @aineotoole.bsky.social @peacockflu.bsky.social @HouriyahTegally - 19th May www.oxfordmartin.ox.ac.uk/events/what-...

01.05.2025 13:12 β€” πŸ‘ 20    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0
Estimation of the Epidemiological Characteristics of Scabies Introduction: Scabies is a contagious skin disease caused by the infestation of the skin by the Sarcopes scabiei mite, causing an itchy rash. Scabies affects ov

πŸ“’ New preprint!

We estimate the serial interval of scabies and characterise its transmission dynamics in the Netherlands over >10 yrs β€”offering new insights into the spread of a neglected but re-emerging disease. (1/4)

πŸ”— papers.ssrn.com/sol3/papers....

#IDSky #EpiSky #AcademicSky #NTD

13.04.2025 07:10 β€” πŸ‘ 14    πŸ” 5    πŸ’¬ 2    πŸ“Œ 0

Increased distrust of health system due to polarised beliefs?

07.04.2025 05:07 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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A Behaviour and Disease Model of Testing and Isolation There has been interest in the interactions between infectious disease dynamics and behaviour for most of the history of mathematical epidemiology. This has included consideration of which mathematica...

New Preprint! There has been a lot of work on models coupling behaviour with disease dynamics, typically (and understandably) agnostic about the exact behaviour. Here we consider specifically testing and isolation, providing mathematical and numerical analyses.

arxiv.org/abs/2504.02488

04.04.2025 15:18 β€” πŸ‘ 16    πŸ” 4    πŸ’¬ 2    πŸ“Œ 2

I think part of the problem in that case is that performance management is underused in academia, in favour of just waiting out someone's contract and not renewing. Perhaps if formal performance management were done more effectively, frustrations would not spill out onto a more personal level.

02.04.2025 23:42 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

I agree when it's a case of personality clash. More difficult cases I have witnessed have been when a junior colleague is underperforming, and senior colleagues stop offering opportunities in a way that could be perceived as unsuppportive.

02.04.2025 23:42 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Saying β€˜pandemic is over,’ NIH institute starts cutting COVID-19 research Grant terminations halt research on improving vaccinations and preventing future pandemics

...a β€œpointless, ill-advised move that will hurt U.S. science and pandemic readiness,” says Charles Rice, a Nobel Prize–winning virologist at Rockefeller University

www.science.org/content/arti...

25.03.2025 21:47 β€” πŸ‘ 76    πŸ” 51    πŸ’¬ 1    πŸ“Œ 5
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Influenza of avian origin confirmed in a sheep in Yorkshire Influenza of avian origin (H5N1) has been confirmed in a single sheep in Yorkshire.

The UK has announced a case of avian flu virus #H5N1 detected in a sheep (on a farm with infected birds). I think some of the significance of this (and the wider picture) is being missed in a lot of the reporting. So a short thread...
πŸ§ͺ #IDsky
www.gov.uk/government/n...

24.03.2025 12:03 β€” πŸ‘ 119    πŸ” 61    πŸ’¬ 2    πŸ“Œ 2
Intrinsic OASL expression licenses interferon induction during influenza A virus infection Effective control of viral infection requires rapid induction of the innate immune response, especially the type I and type III interferon (IFN) systems. Despite the critical role of IFN induction in ...

Excited to share @joelrc.bsky.social 's new paper examining the factors underlying cell-to-cell heterogeneity in interferon induction during flu infection:

www.biorxiv.org/content/10.1...

18.03.2025 18:46 β€” πŸ‘ 55    πŸ” 22    πŸ’¬ 3    πŸ“Œ 0
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Fully-funded PhD opportunity in mathematical biology and applied mathematics with Pascal Buenzli and me at Queensland University of Technology in Brisbane, Australia. Details at smb.org/Member-Forum... @smbmathbiology.bsky.social

18.03.2025 06:06 β€” πŸ‘ 20    πŸ” 17    πŸ’¬ 1    πŸ“Œ 0
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A stitch in line: mathematics and one-stitch Sashiko Published in Journal of Mathematics and the Arts (Ahead of Print, 2025)

I wrote and published a review for a new book β€œA stitch in line: mathematics and one-stitch Sashiko” by Katherine Seaton.

If you’d like to read it, Taylor & Francis gave me 50 free online copies of the article to share with friends and colleagues. Get one here:

www.tandfonline.com/eprint/CUDBX...

02.03.2025 18:35 β€” πŸ‘ 18    πŸ” 5    πŸ’¬ 3    πŸ“Œ 0

The candidate will have the opportunity to analyse the behaviour of these models, and infer model parameters using Bayesian statistics. Data for existing antivirals and/or antivirals under development will be generated by collaborators at the WHO Centre for Reference and Research on Influenza.

19.02.2025 22:06 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

We are advertising a PhD position! The project will develop mathematical models for influenza infection within the host, incorporating the effects of antiviral treatment. Domestic and international applicants welcome.

19.02.2025 22:06 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
UK Mathematical Biology Conference

Excited to announce that registration for UK Maths Bio 2025 is open. We have an exciting list of confirmed speakers and are looking for more exciting talks and posters from the community. Please submit your abstract by 31 March 25.

ukmathbioconference.github.io

19.02.2025 15:54 β€” πŸ‘ 13    πŸ” 9    πŸ’¬ 1    πŸ“Œ 0

School closures?

11.02.2025 05:49 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Deepening our understanding of cross-species antibody responses to H5Nx influenza viruses at The Pirbright Institute on FindAPhD.com PhD Project - Deepening our understanding of cross-species antibody responses to H5Nx influenza viruses at The Pirbright Institute, listed on FindAPhD.com

Just out: PhD opportunity with Dr Marie Di Placido, Dr Stephen Dunham, Prof Munir Iqbal, Prof. Janet Daley and myself looking at how different livestock species make antibody responses to H5N1.

www.findaphd.com/phds/project...

06.02.2025 14:42 β€” πŸ‘ 24    πŸ” 10    πŸ’¬ 0    πŸ“Œ 0
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Details : Research Fellow in Multiscale Mathematical Modelling of Cell Biology : The University of Melbourne Careers at The University of Melbourne

[Please share] We're hiring a postdoc in Mathematical Biology at The University of Melbourne! Come and work with us on a collaborative project looking at how to predict biological behaviour across multiple scales. Feel free to reach out, details are here: jobs.unimelb.edu.au/en/job/91913...

24.01.2025 04:17 β€” πŸ‘ 9    πŸ” 5    πŸ’¬ 0    πŸ“Œ 2
https://doi.org/10.48550/arXiv.2502.00071

A huge thank you to Nefel Tellioglu, Jessica Stockdale, Julie Spencer, Wasiur Rahman Khuda Bukhsh, @joelcmiller.bsky.social and Cameron Zachreson for including me on this @matrix-inst.bsky.social project we just preprinted results from

t.co/9ioaiNWMQa πŸ€“

06.02.2025 17:57 β€” πŸ‘ 10    πŸ” 8    πŸ’¬ 1    πŸ“Œ 0

Amazing opportunity: a few PhD positions in Health Analytics, Epidemic Modelling and Health Economics available with myself and colleagues from @mrc-outbreak.bsky.social, @ccmid.bsky.social and @ukhsa.bsky.social. Please apply/circulate widely!

29.01.2025 13:39 β€” πŸ‘ 25    πŸ” 19    πŸ’¬ 1    πŸ“Œ 1

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