Gulbenkian Institute for Molecular Medicine

Pipetting scRNA-seq data into computational cells Single-cell transcriptomics is transforming biology, uncovering hidden cell states, dynamic transitions, and intricate interactions across systems from immunity to cancer. Yet as these technologies s…

@EMBO Practical Course

Pipetting scRNA-seq data into computational cells

18 – 23 May 2026 | Oeiras/Lisbon, Portugal @gimmfoundation.bsky.social

Registration open!

Concurso CaixaResearch de Investigação em Saúde Distingue Investigadores da Fundação Champalimaud e da Fundação GIMM | Champalimaud Foundation Quatro Investigadores Principais de duas instituições – a Fundação Champalimaud (FC) e a Fundação GIMM (GIMM) – receberam financiamento do Concurso CaixaResearch de Investigação em Saúde para o estudo...

🧑‍🔬🏆Joe Paton & @minuttilab.bsky.social from @champalimaudf.bsky.social and 7 other PIs from @gimmfoundation.bsky.social, @ucoimbra.bsky.social and @i3suporto.bsky.social have won #CaixaResearch funding 👏
👉 www.fchampalimaud.org/news/caixare...
@caixaresearch.bsky.social

The lack of specific targets in many tumours ⬇️ the effectiveness of immunotherapies.

With a #HealthResearch grant ➕ FCT João Lacerda (@gimmfoundation.bsky.social) is developing CAR-T cells that target a molecule found almost exclusively in tumours to improve therapies.

https://tinyurl.com/ykbcmcjv

Damage to telomeres, the ends of chromosomes, can initiate cancerous processes.

With a #HealthResearch grant, Claus Maria Azzalin (@gimmfoundation.bsky.social) is studying the role played by TERRA RNA in telomere repair, which could improve our understanding of cancer.

https://tinyurl.com/yjh7j59c

Front row view of our Maria smoothly presenting her MSc dissertation work on the isoform-specific impact of mutations in CDKN2A in cancer at the Oncobiology Club @gimmfoundation.bsky.social. 💻🧬👏

YouTube video by GIMM Gulbenkian Institute for Molecular Medicine Ep 4: Como é que um medicamento mata bactérias? (com Isabel Gordo)

Podcast com Isabel Gordo, Group Leader no Gulbenkian Institute for Molecular Medicine (@gimmfoundation.bsky.social):

"Como é que um medicamento mata bactérias?"
YouTube: youtu.be/wRyYYa2D5i0
Spotify: open.spotify.com/episode/1AqQ...

Group photo of the EU-LIFE Strategy Meeting 2025 at FMI, Basel.

EU-LIFE Strategy Meeting 2025 wrapped up in #Basel with strong support, constructive exchanges and a very positive atmosphere.

A big thanks to the @fmiscience.bsky.social team for fostering a welcoming environment for productive, forward-looking discussions!

Read more 🔗 eu-life.eu/newsroom/new...

Homeostatic control of energy metabolism by monocyte-derived macrophages | The EMBO Journal imageimageMacrophages play critical roles in the homeostatic control systems that maintain vital parameters within physiological ranges. This study characterizes how mouse monocyte-derived macrophages...

🧵 Thrilled to share our new work in @embojournal! Over a century after Metchnikoff recognized macrophages as central to organismal homeostasis, we reveal how they act as metabolic guardians through an unexpected mechanism.
www.embopress.org/doi/full/10....
(1/9)

Nice to meet the representatives of the Kochard Foundation @gimmfoundation.bsky.social and spend the afternoon talking about T cells and mucosal immunology, shared interests and potential collaborative projects.

We also visited Isabel Gordo's lab at @gimmfoundation.bsky.social (Oeiras) and ran into a familiar face, @martalourenco21.bsky.social former PhD candidate at our lab

This picture was taken right before The Boss' presentation at @gimmfoundation.bsky.social

We initially thought people were just a bit shy but, as it turned out, we were participating in the mandatory drills due to high seismic activity in the area 🤔

Safety first!!

Now published on @plos.org Computational Biology!

Same findings as the preprint, with improved analyses suggested by reviewers!

Check it out and let us know how RepliFlow works for you!

journals.plos.org/ploscompbiol...

Filipa with Leonor, Domingos, Pedro and Madalena standing in front of a colourful mural reading “Where will curiosity take you?” at the GIMM Foundation, Oeiras Campus.

What a pleasure visiting @gimmfoundation.bsky.social in Lisboa -huge thanks to Leonor Saúde for the warm hospitality! Loved exchanging ideas w students, postdocs & faculty about all things #devbio & #regeneration, and meeting old friends in a place that always inspired my curiosity -until next time!

🔬 Community Workshop #1: "Intro to Instrumentation QC in Light Microscopy"
🔹 Learn to monitor laser power
🔹 Record & inspect PSFs
🔹 Analyze data using FIJI + MetroloJ_QC

👩‍🔬Facilitators from @gimmfoundation.bsky.social, @crg.eu & Nova Medical School (NMS).

Let’s build better #microscopy!

#SPAOM2025

Leonor Saude, GIMM

Next, Leonor Saude, from @gimmfoundation.bsky.social, talked about her work using zebrafish and the evolutionary comparisons with mice to pursue spinal cord regeneration in mammals.

Nuno Barbosa-Morais, GIMM

Then, it was the turn of Nuno Morais ( @nmoraislab.bsky.social ), from GIMM ( @gimmfoundation.bsky.social ) and coordinator of @biomics-twinning.bsky.social , telling us about a cool project on CDKN2A.

Cracking organisms’ energy code Researchers define rules governing how growing microorganisms use energy efficiently

Jonathan Rodenfels @mpi-cbg.de, Pablo Sartori @gimmfoundation.bsky.social, and Tommaso Cossetto identified two thermodynamic rules governing the growth and energy utilization of single-celled organisms. Publication in @nature.com Communications. www.mpi-cbg.de/news-outreac...

The paper was out a few months ago, but it is definitely worth a recap. From Rui Oliveira Lab, check it out: gimm.pt/news/seeing-...

It was such a pleasure to visit @gimmfoundation.bsky.social in beautiful Lisbon and to discuss science with students and faculty. So much great science going on here. Thank you, @marcveld.bsky.social for the hospitality.

Inspiring talk from @sanderlab.bsky.social at @gimmfoundation.bsky.social on viral infections (SARS-COV-2 and Influenza), lung pathology and the critical role of macrophages!

"Podemos vir não só a rejuvenescer um órgão, mas todo o organismo". Entrevista à investigadora Joana Neves Com muitas questões ainda por esclarecer sobre o envelhecimento, a investigadora portuguesa lidera um laboratório que se foca no aumento da qualidade de vida, através da medicina regenerativa.

We couldn’t be happier to see Joana Neves research featured and explained in Observador.

Together with Pedro Sousa-Victor, the scientist leads a study focused on cellular therapies that may help people at an advanced age achieve a better quality of life.

🔗 shorturl.at/ZUP07

Embracing health & well-being as our mission. To innovate in a field so vast, all it takes is a little curiosity.

🧪 Promote & support research dedicated to human health
🧪 Translate scientific discoveries into practical applications
🧪 Shape brilliant minds
🧪 Engage with society

gimm.pt

For 3 days, Pavilhão de Portugal became the stage for bold ideas, fresh perspectives, and hands-on experiences around aging and longevity.

Thank you to all the speakers, partners, and everyone who joined us for the very first edition of GIMM Fest.

Transferrin Receptor 1-targeted polymersomes therapy for Colorectal Cancer Colorectal cancer (CRC) ranks among the most common cancers and is the second leading cause of cancer-related deaths. The high mortality associated wi…

It’s OUT! 📢
I am thrilled to share our latest work on nanoparticles to target CRC 🎯
I’m incredibly proud of my team!
A big thank you to @becarios.bsky.social @lacaixa.bsky.social and @gimmfoundation.bsky.social for making this possible!

www.sciencedirect.com/science/arti...

The inaugural GIMM Fest meeting has started. The main theme this year is questions in ageing. This of course is relevant to all biomedical science fields.

Importantly, Saturday is for the general public, with many events!

gimm.pt/gimm-festival/

@gimmfoundation.bsky.social

A terrific @gimmfoundation.bsky.social Festival in Lisbon.

It was great to debate how to build a unifying theory of aging.

Fundação Francisco Manuel dos Santos will join #GIMMFest Sept 6.
“What are the impacts of aging on the economy & society?”

🔗 gimm.pt/gimm-festival

This session will be in Portuguese with Portuguese Sign Language Interpretation.

We’re excited to welcome Alexandra Lopes from FLUP to #GIMMFest on Sept 6, where she’ll join an important discussion about how aging impacts our economy & society.
🔗 gimm.pt/gimm-festival/#program

This session will be in Portuguese with Portuguese Sign Language Interpretation.

What’s happening on Sept 6? #GIMMFest with a full day of discovery & celebration. Free entry! Immersive experiences, 4 engaging talks & space to explore big ideas in aging.
🔗 gimm.pt/pt-pt/gimm-festival

The sessions in auditorium will be in Portuguese with Portuguese Sign Language Interpretation.

Bruno Nogueira, a comedian & author, is 1 of many speakers we’re excited to have at #GIMMFest, diving into the funny, strange, & sometimes surprising lessons that come with getting older!

🔗 gimm.pt/gimm-festival/

This session will be in Portuguese with Portuguese Sign Language Interpretation.