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Hepworth Lab

@hepworth-lab.bsky.social

Mucosal Immunology Lab at the University of Manchester

913 Followers  |  487 Following  |  37 Posts  |  Joined: 13.11.2024  |  2.1376

Latest posts by hepworth-lab.bsky.social on Bluesky

@societymucosalimm.bsky.social
@britsocimm.bsky.social

09.10.2025 14:40 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Research Associate - mucosal immunology and innate lymphoid cell (ILC) biology:Oxford Road The Hepworth laboratory within the Lydia Becker Institute of Immunology and Inflammation at the University of Manchester wish to appoint a laboratory-based Research Associate to an exciting project in mucosal immunology and innate lymphoid cell (ILC) biology.

Postdoc opportunity in the lab for a budding ILC biologist.

Informal enquiries welcome - please spread the word.

Ad closes in 4 weeks.

www.jobs.manchester.ac.uk/Job/JobDetai...

09.10.2025 14:39 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0

Nice article about the community of Lister fellows in Manchester!

01.10.2025 16:52 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Research Technician in the Glyco-immunology (Dyer) Lab:Oxford Road Include: background, duties, essential skills and experience, length of contract, full or part-time. Keep to 150 words.

We now have a very exciting technician post advertised as part of our long term Wellcome Trust funded team investigating the role of the glycocalyx during CNS inflammation. Supporint the lab, developing glycan analysis and research experience www.jobs.manchester.ac.uk/Job/JobDetai...

22.09.2025 10:39 β€” πŸ‘ 6    πŸ” 12    πŸ’¬ 0    πŸ“Œ 1

So pleased to see our research out in #ScienceImmunology demonstrating that CLPs regulate airway remodelling during allergy 🫁 Really proud of the hard work and collaboration that went into this project πŸ«±πŸΌβ€πŸ«²πŸ½. Definitely one to check out for lovers of the immuno-matrix & pretty picturesπŸ‘‡πŸΌπŸ”¬

20.09.2025 18:04 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Lecturer in Neuroimmunology, Medicine, Medical Sciences & Nutrition (MED243A) | The University of Aberdeen Browse and apply for current job openings at the University of Aberdeen across various schools, departments and roles, including admin and academic.

Aberdeen is hiring - Neuroimmunology Lectureship! Really exciting opportunity to join our supportive, collaborative and multidisciplinary Institute to carry out cutting edge translation research. Not to mention the scenery in the North East of Scotland is amazing www.abdn.ac.uk/jobs/vacanci...

19.09.2025 07:55 β€” πŸ‘ 10    πŸ” 12    πŸ’¬ 0    πŸ“Œ 0
Research Associate in in Neuro-Immunology and Extraceullar Matrix Biology (ImmunoMatrix):Oxford Road Our Glyco-Immunology (Dyer) lab has produced published and preliminary data demonstrating that an under-appreciated structure, the glycocalyx, on endothelial- and immune- cells regulates immune cell recruitment by:

We have a new Postdoc position advertised as part of our recent long-term Wellcome funding to join an established Postdoc and technician. I’m so excited to explore the role of the glycocalyx in CNS-inflammation. So many tools and expertise to work with! www.jobs.manchester.ac.uk/Job/JobDetai...

12.09.2025 15:47 β€” πŸ‘ 19    πŸ” 18    πŸ’¬ 1    πŸ“Œ 3
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Intestinal challenges shape the polarisation of protective dural memory CD4 T cells The meninges house several innate and adaptive immune cell populations[1][1]–[3][2]. These predominantly localise within the dura mater and include gut-derived IgA-secreting plasma cells[4][3]. Whethe...

New paper alert! πŸŽ‰ Check it out here: biorxiv.org/content/10.1... Here we show that intestinal bacterial, helminth and fungal challenges polarise CD4 T cell populations in the dural meninges.

16.09.2025 14:43 β€” πŸ‘ 14    πŸ” 5    πŸ’¬ 2    πŸ“Œ 0

Thanks Fiona!

10.09.2025 19:31 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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FindAPhD : MRC CoRE in Exposome Immunology at The University of Manchester Apply for a PhD: MRC CoRE in Exposome Immunology at The University of Manchester

Following on from the PDRA adverts, we are also happy to announce the MRC Core in Exposome Immunology PhD scheme, details below. Reach out with any questions
www.findaphd.com/phds/program...
www.bmh.manchester.ac.uk/study/resear...

09.09.2025 12:04 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1
Research Associate in MRC CoRE in Exposome Immunology (Defining Acute and Chronic Mucosal Responses to Pollution Exposure):Oxford Road Project Title: Defining Acute and Chronic Mucosal Responses to Pollution Exposure

New Postdoc position as part of the recently awarded MRC Core in Exposome Immunology, led by Jo Konkel here @lydiabeckeriii.bsky.social. Job ad and more info below:
www.jobs.manchester.ac.uk/Job/JobDetai...

www.bmh.manchester.ac.uk/research/ins...

08.09.2025 09:51 β€” πŸ‘ 12    πŸ” 13    πŸ’¬ 0    πŸ“Œ 1

closing at the end of this week!

08.09.2025 09:07 β€” πŸ‘ 3    πŸ” 13    πŸ’¬ 0    πŸ“Œ 0
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Research Associate in Microbial Ecology:Oxford Road

Another PDRA position! Join our team exploring how the mammalian immune system shapes microbiome ecology & evolution, and vice versa. In collaboration with @hepworth-lab.bsky.social funded by the @wellcometrust.bsky.social

www.jobs.manchester.ac.uk/Job/JobDetai...

27.08.2025 08:52 β€” πŸ‘ 22    πŸ” 18    πŸ’¬ 0    πŸ“Œ 2
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Cell Symposia: Host-microbiome dynamics
May 10–12, 2026 | Bruges, Belgium

by @cp-immunity.bsky.social @cp-cellhostmicrobe.bsky.social and @cp-trendsmicrobiol.bsky.social

www.cell-symposia.com/microbiome-2...

14.08.2025 14:08 β€” πŸ‘ 35    πŸ” 12    πŸ’¬ 2    πŸ“Œ 1

Congrats!!

16.07.2025 19:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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New Β£50m MRC Centre to study how environmental exposures cause chronic inflammatory diseases A groundbreaking Β£50M research centre at Manchester and Oxford will explore how environmental exposures, like pollution and microbes, rewire our immune system and drive chronic inflammatory diseases.

🚨 A new £50M MRC Centre at @manchester.ac.uk and @ox.ac.uk will explore how pollution, microbes & other environmental exposures rewire our immune system and cause chronic inflammatory diseases.
#Exposome #ImmunoSky

sites.manchester.ac.uk/lydia-becker...

16.07.2025 09:41 β€” πŸ‘ 38    πŸ” 11    πŸ’¬ 2    πŸ“Œ 1
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Centre to study how exposome causes chronic inflammatory disease A new Medical Research Council (MRC) centre will investigate how the environment interacts with our immune system to trigger chronic inflammatory diseases.

Super excited to announce that MRC has funded a new Centre of Research Excellence in Exposome Immunology. Working together, Manchester and Oxford are going to tackle a major challenge of our times. For those who wonder what the Exposome is - see yesterday's posts! www.ukri.org/news/centre-...

16.07.2025 10:55 β€” πŸ‘ 56    πŸ” 16    πŸ’¬ 1    πŸ“Œ 1
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Centre to study how exposome causes chronic inflammatory disease A new Medical Research Council (MRC) centre will investigate how the environment interacts with our immune system to trigger chronic inflammatory diseases.

www.ukri.org/news/centre-...

16.07.2025 10:03 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Big news! Manchester, together with colleagues in Oxford, have been awarded an MRC CoRE in Exposome Immunology!! Exciting times ahead to uncover how pollution and other environmental factors worsen inflammatory diseases!!

16.07.2025 09:01 β€” πŸ‘ 19    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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ILC3s are a RORΞ³t+ APC that sense the microbiota through STING to induce microbiota-specific Treg cells
www.cell.com/immunity/ful... @cp-immunity.bsky.social

16.06.2025 15:24 β€” πŸ‘ 6    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0

Congratulations!!

02.06.2025 15:59 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Journal I guess, we didn't know until today

14.04.2025 20:29 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

This is awesome, any chance of some print copies so the lab can frame for posterity πŸ˜‰

14.04.2025 15:17 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

So cool to see our recent review highlighted on the cover of @mucosalimmunol.bsky.social !!

14.04.2025 15:17 β€” πŸ‘ 13    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

Come and work with me!

The Nature Micro team is expanding and we're looking for someone to champion microbial ecology, plant micro & related areas for the journal

Knowledge of microbial ecology/plant micro is desirable but we're open to applications from all microbiologists

Link below πŸ‘‡

11.04.2025 16:14 β€” πŸ‘ 100    πŸ” 99    πŸ’¬ 1    πŸ“Œ 1

I for one bow down to our new AI overlords, I'm sure we will all get a nice universal income to compensate us for our obsoleteness don't worry! 🀣

08.04.2025 16:23 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0
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Brain sensing of metabolic state regulates circulating monocytes Brain-initiated hunger signals control circulating monocyte dynamics.

Our latest study
@science.org #Immunology on perception of #hunger and #immunity.

#BrainBody #Melanocortin #AgRP #POMC neurons. #Brain-liver axis. Permissive action of #stress #hormones.

@ukri.org @fbmh-uom.bsky.social

www.science.org/doi/10.1126/...

07.04.2025 14:33 β€” πŸ‘ 44    πŸ” 13    πŸ’¬ 1    πŸ“Œ 2

A pleasure to be a part of this study with @dagostinolab.bsky.social revealing how hunger sensing neurons in the brain act to modulate circulating monocyte levels. Out now in #scienceimmunology

08.04.2025 07:08 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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On the April cover of #ScienceImmunology: The brain’s perception of hunger (rather than nutrient availability) regulates circulating immune cell dynamics. Read more here:
www.science.org/doi/10.1126/...

05.04.2025 18:39 β€” πŸ‘ 12    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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Scientists cast new light on how fasting impacts the immune system New research from The University of Manchester may reshape our understanding of what happens to the immune system when we fast.Funded by the Biotechnology and Biological Sciences Research Council (BBS...

www.manchester.ac.uk/about/news/s...

05.04.2025 09:52 β€” πŸ‘ 18    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1

@hepworth-lab is following 20 prominent accounts