Graphical abstract depicts automated setup to generate 3D cardiac mini tissues consisting of 3 cell types seeded into 384 well plates. The cardiac tissues are monitored using calcium traces to detect arrhythmias and subsequent rescue after compound addition.
🔥Super excited to drop our recent preprint🔥
biorxiv.org/cgi/content/...
Here, we automated the generation of 3D Cardiac Microtissues and performed a small high-throughput screen to identify several novel anti-arrhythmic compounds for CPVT1 🧪❤️
#Cardiosky #Science #hiPSC #Arrhythmia #Stemcell
04.12.2024 15:13 — 👍 12 🔁 3 💬 1 📌 0
Personalized miniorgans could speed treatments for rare diseases
Method shrinks time for testing tailored RNA drugs from months to weeks
🥼 A new personalized method reduces the time spent tailoring RNA drugs—from months to weeks. In a @nature.com paper, scientists used patient-derived cardiac #organoids to predict how rare genetic diseases respond to treatments.
via @science.org
06.02.2025 17:26 — 👍 5 🔁 1 💬 0 📌 0
Created a starter pack focusing on disease modeling in a dish using stem cells! 🧪🔬
Please (self)nominate anyone you think should be added to the list and repost so it finds the right people ❤️
hPSC Disease Modeling: go.bsky.app/EpWsxNG
For a good general stem cell pack go here: go.bsky.app/UTW4d7b
05.12.2024 15:53 — 👍 39 🔁 16 💬 14 📌 1
Would love to be considered ;-)
06.02.2025 21:05 — 👍 1 🔁 0 💬 1 📌 0
A thread about being wrong:
5 years ago, we wrote a paper about how how newly enfranchised 16-year-olds vote in Austria. But we were wrong.
This year, @elisabethgraf.bsky.social, @schnizzl.bsky.social, Sylvia Kritzinger and I are setting the record straight: authors.elsevier.com/c/1juT5xRaZk...
21.11.2024 18:00 — 👍 642 🔁 156 💬 26 📌 54
