Farshid Guilak's Avatar

Farshid Guilak

@farsh-g.bsky.social

@ShrinersStLouis @wustlortho @washubme @washudevbio @wustlCRM @theNAMedicine @theNAEng @AcadofInventors @cytexortho @MyAOCConnect #racquetball

335 Followers  |  376 Following  |  29 Posts  |  Joined: 31.12.2024  |  1.8546

Latest posts by farsh-g.bsky.social on Bluesky

Thanks for all your participation in the session!

05.08.2025 19:54 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks so much @ardemp.bskyverified.social!

21.07.2025 20:37 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Chondrocyte-specific knockout of Piezo1 and Piezo2 protects against post-traumatic osteoarthritis structural damage and pain in mice - Arthritis Research & Therapy Background Osteoarthritis (OA) is a debilitating joint disease characterized by cartilage degeneration, synovial inflammation, and bone remodeling, with limited therapeutic options targeting the under...

Exciting new study on the role of PIEZOs in Chondrocytes! Relevance to arthritis and pain. From: @farsh-g.bsky.social & @kelseyhcollins.bsky.social
arthritis-research.biomedcentral.com/articles/10....

21.07.2025 20:15 β€” πŸ‘ 33    πŸ” 6    πŸ’¬ 2    πŸ“Œ 3
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Congrats to Amanda Cimino and team on her latest paper in @JCRnEDITORS - she developed new synthetic chronogenetic gene circuits that allow controlled drug delivery at precise times day using various elements of the circadian clock! doi.org/10.1016/j.jc...

23.06.2025 12:00 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Huge congrats to Dr. Amanda Cimino for an outstanding presentation and defense - her committee said it was time for a "PhD+" degree. Amazing work!

11.06.2025 20:02 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Chronotherapy in RA Treatment: Tantalizing but Understudied Research is evaluating chronotherapy to target drugs to reduce morning stiffness and flares in rheumatoid arthritis, but it has a long way to go before it reaches the clinic.

Chronotherapy in Rheumatoid Arthritis Treatment: Tantalizing but Understudied
www.medscape.com/viewarticle/...

03.06.2025 17:05 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 1
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9 Federally Funded Scientific Breakthroughs That Changed Everything

We don’t always know what questions will change the world.

But public science has a way of answering them anyway.

Federal science funding isn’t just lines in a budget. It’s a vote for progress, for possibility.

www.nytimes.com/2025/05/16/s...

22.05.2025 13:49 β€” πŸ‘ 129    πŸ” 41    πŸ’¬ 0    πŸ“Œ 4
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Most studies of cartilage mechanobiology study the upregulation of chondrocyte gene expression and biosynthesis with mechanical loading. Check out our recent paper where Daniel Palmer studied the down-regulated "mechanome" with Piezo1 or TRPV4 activation. www.tandfonline.com/doi/full/10....

22.05.2025 15:16 β€” πŸ‘ 7    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Your research on Ion Channel Regulation might be the next watershed discovery! Join FASEB for the latest findings at #ICRSRC with keynote speaker @farsh-g.bsky.social
and organizers @roseedixon.bsky.social and Jonathan Silva. Submit your abstract by June 8 and save your space now! buff.ly/A3wmAbp

22.05.2025 13:03 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Congrats to Amanda Cimino for her latest paper creating a chronogenetic gene circuit that automatically delivers anti-inflammatory biologic drugs in response to inflammation or circadian signal! jbioleng.biomedcentral.com/articles/10....

20.05.2025 11:50 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1
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Lots of celebrations this month in the Guilak Lab! Congrats to Xinyi Melissa Li and Katelyn Lipa for passing their qualifying exams with flying colors!

13.05.2025 19:18 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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🚨 Big updates!
βœ… Successfully defended my PhD thesis:
β€œMultiscale Modeling of Chondrocyte Mechanobiology: Insights into Degeneration and Regeneration”
βœ… Joined the lab of @farsh-g.bsky.social at WashU St Louis as a Rita Levi-Montalcini Postdoc Fellow in regenerative medicine!
Grateful & excited !

08.05.2025 20:22 β€” πŸ‘ 8    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Please widely share these 3 new advocacy letter templates with your colleagues.

@lolauic.bsky.social @orssociety.bsky.social @bmes-cmbe.bsky.social @aapmhq.bsky.social @acadrad.bsky.social @ceschmidt2024.bsky.social @settonlab.bsky.social @tejaladesai.bsky.social @farsh-g.bsky.social

05.05.2025 18:40 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 1    πŸ“Œ 1
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Adipose-derived leptin and complement factor D mediate osteoarthritis severity and pain Osteoarthritis and knee joint pain are driven by systemic leptin and complement factor D secreted by adipose tissue.

Join us for our quarterly C-COMP journal club, featuring this exciting new paper by the team of @kelseyhcollins.bsky.social and @farsh-g.bsky.social Monday May 12th 10 am CST- ask us how to register!

www.science.org/doi/full/10....

02.05.2025 19:08 β€” πŸ‘ 10    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1
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Congrats to Sophie Paradi on a fantastic Master's thesis and defense! Amazing work and collaboration with Erica Ely and many others in the Guilak Lab

01.05.2025 12:18 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Ion channel research can have major consequences for cancer and cardiovascular disease treatments. Join FASEB at #ICRSRC for the latest findings with keynote speaker @farsh-g.bsky.social and organizer @roseedixon.bsky.social. Check out the full program and save your space: buff.ly/d213NE1

28.04.2025 17:09 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Congrats β€ͺ@kelseyhcollins.bsky.social‬ on another tour de force, shedding further light into the relationship between obesity and OA! The more we learn, the more complex it gets... Fantastic collaboration with the June lab and WashU Rheumatology!

25.04.2025 19:24 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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put me in, coach...

24.04.2025 21:53 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Join us today for our AOC Thought Leaders Webinar: Managing the Research Enterprise β€” for anyone navigating the evolving landscape of academic orthopaedics.

April 24 | 4:00 PM ET
Register Here: lnkd.in/eTrzEem6

Joint the AOC at myaocconnect.com!

24.04.2025 12:13 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Congrats Dr. Jackie Garcia on an amazing dissertation on defense "Characterizing PIEZO1 Mechanotransduction in Articular Chondrocytes"!

10.04.2025 20:55 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Excited for our most recent publication mapping macrophage populations in the synovium with knee injury and obesity! Great work by @nharasymowicz.bsky.social and team!

07.04.2025 21:55 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Congrats Hope!

24.03.2025 19:07 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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A Definitive Guide to Racquet Sports, From Tennis to Pickleball to Padel There are so many racquet sports with varying levels of difficulty, benefits, and #vibes. Find the one that's right for you here.

www.menshealth.com/health/a6375...

18.03.2025 17:31 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Support Strong FY25 Funding for Biomedical Research by March 14 Use AIMBE's letter template below, edit as needed, or create your own message to your Members of Congress on issues that matter. Enter your contact information on the left, and your letter will be rou...

The 3/14 deadline to finalize the FY2025 budget is fast approaching! βŒ›

AIMBE has developed a new advocacy letter (<1 min to send) for the scientific community to urge Congress to support our federal science agencies, including NIH, NSF, FDA, ARPA-H, CDMRP, and more πŸ‘‡

takeaction.io/aimbe/suppor...

11.03.2025 14:29 β€” πŸ‘ 29    πŸ” 25    πŸ’¬ 2    πŸ“Œ 1
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Engineered stem cells automatically deliver arthritis drugs at prescribed times of day β€œThis technology has the potential to change a lot of lives.

Engineered stem cells automatically deliver arthritis drugs at prescribed times of day
apnews.com/press-releas...
www.nature.com/articles/s41...

07.03.2025 13:45 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Thanks Amro!

05.03.2025 14:51 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks Duygu!

05.03.2025 14:51 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Great collaboration with Erik Herzog and Qing Jun Meng labs!

05.03.2025 13:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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We’ve created a new field called β€œchronogenetics”: controlling gene expression with the cell’s internal clock! Lara Pferdehirt & Anna Damato made living implants that sync to the body & automatically deliver biological drugs on a 24 hr cycle. www.nature.com/articles/s41...

05.03.2025 13:00 β€” πŸ‘ 17    πŸ” 5    πŸ’¬ 5    πŸ“Œ 0
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On #RareDiseaseDay, we are excited to publish Zainab Harissa's paper showing that rare, dysplasia-causing mutations in the ion channel TRPV4 alter the response of chondrocytes to mechanical loading. journals.physiology.org/doi/abs/10.1...

28.02.2025 22:21 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

@farsh-g is following 20 prominent accounts