SPP2389 - Emergent Functions of Bacterial Multicellularity

Deciphering guanidine assimilation and riboswitch-based gene regulation in cyanobacteria for synthetic biology applications | PNAS Guanidine is well known as a denaturing agent. However, recent studies have demonstrated both the widespread synthesis of guanidine, e.g., in plant...

Our latest paper on Guanidine metabolism in #Cyanobacteria is out @pnas.org
(it's useful as N nutrient but toxic at the same time)

A great collaboration w Klähn lab w small part from us on toxicity😅
@hhu.de @spp2389.bsky.social
@sfb1381.bsky.social @mibinet.bsky.social
www.pnas.org/doi/10.1073/...

Last chance to visit Bakteriopolis at the @tudresden.bsky.social Excellence Days event!

Surface matters! Chitin alters both intraspecies interactions and biofilm architecture in Vibrio cholerae in marine snow

Preprint on @biorxiv-microbiol.bsky.social ⬇️

Cellulose is a critical component in the cell wall of Streptomyces, and accessory proteins involved in its biosynthesis support both its unique cell envelope and multicellular filamentous growth

From Daniel Claessens’ lab in @cp-trendsmicrobiol.bsky.social
#microsky #streptomyces #multicellularity

Bakteriopolis is in Halle at the #SilbersalzFestival this week! Even Come try water kefir, make your own bacterium, and learn about the hidden world of multicellular microbes! #SPP2389 #microsky #wisskomm

Danke an Mainzelmännchen Det für den Besuch! @zdfde.bsky.social

@kostchristian.bsky.social has an open PhD position as a part of #SPP2389 !
#microsky #mevosky

Evolution of One Species Increases Resistance to Invasion in a Simple Synthetic Community - Microbial Ecology The species that make up a microbial community determine its potential function. A major goal of microbial ecology is to make assemblages of microbes — synthetic communities — with targeted applicatio...

Evolution of One Species Increases Resistance to Invasion in a Simple Synthetic Community

Microbial Ecology

link.springer.com/article/10.1...

I’ll second MYM! Seems to be a good allrounder for most of the natural isolates we’ve worked with

Interested in working on microbial interactions and cooperative cross-feeding? Join @kostchristian.bsky.social as a part of #SPP2389 !

From polymicrobial water kefir grains to PCD in biofilms, microorganisms are magnificently multicellular!
Thanks to @embo.org @ibe-barcelona.bsky.social for having Lena Friebel and Thorsten Mascher @tudresden.bsky.social as well as @escolizzi.bsky.social at the
#Multicellverse workshop

You can’t talk about microbial multicellularity without mentioning Streptomyces - check out our collaborator Daniel Rozen’s experimental evolution of these filamentous bacteria!
Thanks @martaalvarez.bsky.social for snapping a pic!
@embo.org #Multicellverse

Our head of #SPP2389 Thorsten Mascher also put the spotlight on the multicellular microbial communities of water kefir - thanks again @evolvedbiofilm.bsky.social !
@embo.org #Multicellverse

Lena brought her research on cannibalism in Bacillus biofilms to the @embo.org multicellularity workshop! Thanks @evolvedbiofilm.bsky.social for the picture! #Multicellverse

Protein condensates determine a cell’s fate Do cells contain a mechanism that decides on their fates? Researchers at ETH Zurich have demonstrated in a new study that large clusters of molecules determine a cell’s future.

All cells – from mammalian cells to microbes – can follow different biological paths. Whether they grow and divide, specialise, age or die depends on the pathway they take. New findings by researchers at ETH Zurich could help influence a cell’s decisions to target diseases such as cancer.

Diurnal rhythm causes metabolic crises in the cyanobacterial mutants of c-di-AMP signaling cascade Biological sciences; Biochemistry; Microbiology; PII-like protein SbtB; c-di-AMP signaling; Cyanobacteria; Carbon/Nitrogen metabolism; Redox imbalance; Photosynthesis; Reactive oxygen species (ROS); C...

A bit late 🙃 but happy to share our recent findings on #cdiAMP signaling in controlling #cyanobacteria #diurnal rhythm in @cp-iscience.bsky.social

www.cell.com/iscience/ful...

#cdiAMP is involved in almost all cellular processes, explaining it's essentiality in #cyano
@hhu.de
@mibinet.bsky.social

PhD position on Regulation and Evolution of Bacterial Multicellularity ( #Streptomyces ) within @spp2389.bsky.social supervised by Natalia Tschowri (Hannover 🇩🇪) and Danny Rozen (Leiden 🇳🇱) with research at both locations

deadline: October 31, 2025

www.uni-hannover.de/en/jobs/id/802

Streptomyces and other filamentous actinomycetes are treasure troves of a vast collection of antibiotic compounds - an evolutionary feature linked to their unique multicellular lifestyle

Curious about kin recognition systems? Take notes from Proteus and Myxococcus!
@ucberkeleyofficial.bsky.social

International Microorganism Day - Microbe Art Contest Winners

Congratulations to our Matthias for winning the @femsmicro.org international microorganism day microbe art contest for best photo and best overall! 🎉🦠
Biofilms truly are beautiful works of multicellular microbial architecture 🏛️

www.internationalmicroorganismday.org/microbeart

A bit late to the party, but happy belated international microorganism day!

The what, when, where, and why of wrinkly morphology in biofilms Wrinkling is a striking emergent behavior that occurs in microbial biofilms across many species. The phenomenon originates from an intricate interplay between e

The what, when, where, and why of wrinkly morphology in biofilms

-in Biophysics Rev

pubs.aip.org/aip/bpr/arti...

We loved hearing @khammerschmidt.bsky.social talk about evolution at the #MultiBac2025 conference this January - check out the @asm.org report on the origins of early microbial life!

A very interesting study by @cyanofur.bsky.social Lab on biofilm formation by filamentous #Cyanobacteria Nostoc

Could be interesting for @spp2389.bsky.social

nph.onlinelibrary.wiley.com/doi/10.1111/...

Congrats to @mcaroec.bsky.social on winning a talk prize at #BACELL2025 !

Our #SPP2389 associated PhD student Luis gave a great talk on the effects of experimental evolution on Streptomyces aggregates and colonies at the #ISBA2025 !

Another #SPP2389 PhD student Martha with a great talk on phase transitions in B. subtilis macrocolonies!
Thanks again to @evolvedbiofilm.bsky.social for capturing the moment! #BACELL2025

One of our SPP PhD students Lena presented her research on cannibalism in B. subtilis biofilms at the #BACELL2025 today!
Thanks to @evolvedbiofilm.bsky.social for snapping a pic!

Only 2 more days until the ISBA! Genna's looking forward to 5 days of nothing but actinomycetes and the beautiful North Sea.
Tot snel!

www.universiteitleiden.nl/isba2025

Antimicrobial efflux and biofilms: an interplay leading to emergent resistance evolution The biofilm mode of growth and drug efflux are both important factors that impede the treatment of bacterial infections with antimicrobials. Decades of work have uncovered the mechanisms involved in b...

Antimicrobial efflux and biofilms: an interplay leading to emergent resistance evolution

@cp-trendsmicrobiol.bsky.social from Rosalind Allen, Frank Schreiber groups (within @spp2389.bsky.social and @microverse.bsky.social)

www.cell.com/trends/micro...

Only a few more weeks until the Long Night of Science (Lange Nacht der Wissenschaften) here in Dresden!

www.wissenschaftsnacht-dresden.de