Congrats!!
17.09.2025 15:27 — 👍 0 🔁 0 💬 0 📌 0
Childhood malnutrition remains a major global health challenge. Our work reveals how organelle crosstalk in neonatal gut cells safeguards nutrition and development — and how its failure resembles Kwashiorkor.
16.09.2025 09:43 — 👍 0 🔁 0 💬 1 📌 0
Martin-Belmonte and Martinez-Martin at CBMSO
🚨 New paper out!
Neonatal enterocytes rely on autophagy & mitophagy to sustain nutrient absorption. Our study demonstrates that the mitochondria–lysosome axis controls the weaning transition and may contribute to childhood malnutrition.
👉https://www.biorxiv.org/content/10.1101/2025.09.09.674148v3
16.09.2025 09:43 — 👍 0 🔁 0 💬 1 📌 0
Thank you Sofia
Best
F
30.04.2025 08:17 — 👍 1 🔁 0 💬 0 📌 0
Graphical model showing the effect of CASM autophagy in lumen resolution of epithelial tubes.
🧪 Canonical autophagy isn’t enough! In our new study, only CASM can coordinate the membrane remodeling needed to build a single lumen in tubes. Read how CASM drives endocytic recycling to drive morphogenesis www.biorxiv.org/content/10.1...
#ScienceTwitter #Autophagy #Morphogenesis #CellPolarity
29.04.2025 07:42 — 👍 2 🔁 1 💬 0 📌 0
ATG16L1 KO H1-human Neural Tube organoids fail to resolve ML at day
5 of development. Cells were stained for actin (red) and nuclei (blue). Dotted lines indicate the lumens.
🚨 New paper out! We reveal that noncanonical autophagy (CASM) is a critical driver of epithelial lumen formation. CASM regulates endocytic recycling and membrane remodeling—without it, cells can’t resolve into a single lumen.
www.biorxiv.org/content/10.1...
29.04.2025 07:37 — 👍 4 🔁 0 💬 0 📌 1
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