Spang Lab

Bacterial RNA promotes proteostasis through inter-tissue communication in C. elegans Nature Communications - Kyriakakis et al. show that bacterial RNA can improve C. elegans healthspan and reduce toxic protein aggregation in muscles. This depends on inter-tissue communication and...

A little stress is good for you in #health #ageing ! #Diet is important! Take a look at our article with Emmanouil Kyriakakis as 1st author!
@unibas.ch
@natcomms.nature.com
@snsf.ch
#Longevity #healthspan
rdcu.be/eI1vZ

01.10.2025 17:14 — 👍 4    🔁 2    💬 0    📌 0

We are thankful to our collaborators from the @spanglab.bsky.social and @maierlab.bsky.social @biozentrum.unibas.ch @unibas.ch

11.08.2025 09:10 — 👍 3    🔁 1    💬 0    📌 0

It was our great pleasure to be part of this exciting project!

15.08.2025 09:15 — 👍 2    🔁 0    💬 0    📌 0

A CRISPR/Cas9 screen reveals proteins at the endosome-Golgi interface that modulate cellular anti-sense oligonucleotide activity Nature Communications - Antisense oligonucleotide (ASO) cellular activity requires endosomal escape. Here, the authors show that disrupting Golgi-endosome protein AP1M1 enhances ASO activity by...

Great collaboration with Liza Malong and Filip Roudnicky from pRED @Roche rdcu.be/et6Nw

30.06.2025 15:30 — 👍 6    🔁 1    💬 0    📌 0

Anne Spang awarded distinction of AAAS Fellow The AAAS has elected Prof. Anne Spang at the Biozentrum, University of Basel, as a Fellow. With this honor, the world’s largest scientific society recognizes her outstanding contributions to the field...

Congratulations to Anne Spang @spanglab.bsky.social for being elected as a new #AAASFellow by @aaas.org ! The world’s largest scientific society recognizes her outstanding contributions to the field of cell #biology and #biochemistry. @unibas.ch
www.biozentrum.unibas.ch/news/detail/...

28.03.2025 08:17 — 👍 44    🔁 9    💬 0    📌 1

We got the cover!!! Check out our new story in EMBO J. #endosomes #c.elegans #membranes #GTPases

17.03.2025 15:18 — 👍 14    🔁 1    💬 0    📌 0

Awesome lab outing: snow shoeing and sledding! Thank you for being such a wonderful team!

28.02.2025 09:42 — 👍 1    🔁 0    💬 0    📌 0

Coordination between ESCRT function and Rab conversion during endosome maturation | The EMBO Journal imageimageEarly endosome maturation requires Rab conversion and ESCRT function; however, how these processes are coordinated remains largely elusive. This study proposes that Rab conversion in both C....

Interested how events are coordinated during #endosome maturation? Check out our latest paper! Congrats Daniel, Samit and Jachen!
www.embopress.org/doi/full/10....

05.02.2025 15:53 — 👍 17    🔁 9    💬 0    📌 1

So let’s do some super science together!!

14.01.2025 16:43 — 👍 2    🔁 0    💬 1    📌 0

I feel humble and honored to receive the Lelio Orci Award 2024. I want to thank my amazing co-workers and trainees who are with me on the pursuit of the understanding how intracellular communication is achieved.

14.01.2025 16:42 — 👍 21    🔁 0    💬 3    📌 1

Me!

26.11.2024 18:02 — 👍 0    🔁 0    💬 0    📌 0