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Mariah Hoye

@mariahhoye.bsky.social

Scientific Project Manager in the NINDS Office of Research Quality Loves high-quality research, particularly in neuroscience and RNA biology Working to change the culture of science Views are my own

1,364 Followers  |  508 Following  |  97 Posts  |  Joined: 22.08.2023  |  2.1868

Latest posts by mariahhoye.bsky.social on Bluesky

An Open Letter to U.S. STEM Leadership on the NSF Graduate Research Fellowship Program An Open Letter to U.S. STEM Leadership on the NSF Graduate Research Fellowship Program

Please share with anyone who cares about NSF support for graduate students and take 30 seconds to sign and leave a comment.

The deadline for the 2025 Graduate Research Fellowship Program is about one month away and literally no one can apply. #NSFGRFP

jasonjwilliamsny.github.io/grfp2025/

25.09.2025 22:09 β€” πŸ‘ 221    πŸ” 274    πŸ’¬ 12    πŸ“Œ 67
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Ending publication bias: A values-based approach to surface null and negative results Sharing knowledge is a fundamental principle within the scientific community, yet null and negative results are still being underreported. This Consensus View discusses the problem of such publication...

I and other participants of the Novel Approaches to Preventing Publication Bias Workshop, hosted by the NINDS Office of Research Quality in May 2024, have published a framework to encourage the publication of null results in science: πŸ§ͺ

journals.plos.org/plosbiology/...

24.09.2025 18:21 β€” πŸ‘ 26    πŸ” 11    πŸ’¬ 1    πŸ“Œ 0
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Ending publication bias: A values-based approach to surface null and negative results Sharing knowledge is a fundamental principle within the scientific community, yet null and negative results are still being underreported. This Consensus View discusses the problem of such publication...

Publication bias continues to skew academic literature. In our new @plosbiology.org article, we outline actionable steps for journals, funders & researchers to ensure all resultsβ€”not only β€œpositive” onesβ€”are valued. A roadmap for more reliable science: journals.plos.org/plosbiology/...

25.09.2025 12:49 β€” πŸ‘ 7    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

IMO, tackling our bias against null studies is essential for improving the culture of science.

We want high-quality science,

BUT we evaluate research and researchers more on the outcome of their work (β€œpositive” findings, novelty, etc.) than the process by which those results were obtained.

25.09.2025 13:04 β€” πŸ‘ 2    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

No publicar todos los resultados de investigaciΓ³n, incluidos los "negativos" es un problema que tenemos que afrontar juntos... @scurry.bsky.social explica mucho mejor que yo lo que contamos en nuestro ΓΊltimo paper. @plosbiology.org

25.09.2025 05:35 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

Grateful to @stephencurryuk.bsky.social and the other participants in this terrific workshop focused on how to combat our bias against publishing negative data (so important!) πŸ‘‡

24.09.2025 18:34 β€” πŸ‘ 7    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Ending publication bias: A values-based approach to surface null and negative results Sharing knowledge is a fundamental principle within the scientific community, yet null and negative results are still being underreported. This Consensus View discusses the problem of such publication...

"Ending publication bias: A values-based approach to surface null and negative results"

Paper out today in PLoS Medicine by many of us who would like to see publication bias reduced or eliminated.

Especially happy that Registered Reports got shout-outs.

journals.plos.org/plosbiology/...

24.09.2025 19:46 β€” πŸ‘ 20    πŸ” 10    πŸ’¬ 1    πŸ“Œ 1
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Ending publication bias: A values-based approach to surface null and negative results Sharing knowledge is a fundamental principle within the scientific community, yet null and negative results are still being underreported. This Consensus View discusses the problem of such publication...

Sharing knowledge is a fundamental principle within the scientific community, yet null and negative results are still being underreported. @scurry.bsky.social &co present a roadmap to a solution that has a role for everyone in the scientific community πŸ§ͺ #Academicsky #reproducibility
plos.io/3VwaU2O

25.09.2025 11:20 β€” πŸ‘ 26    πŸ” 12    πŸ’¬ 1    πŸ“Œ 6
Let’s get negative about scholarly publishing | Reciprocal Space

Let's get negative about scholarly publishing – a new paper (first in a long time for me!) on proposals to tackle the problem of publication bias that emerged from a NINDS workshop held in May last year.
occamstypewriter.org/scurry/2025/... [Direct link to paper: journals.plos.org/plosbiology/...

24.09.2025 18:16 β€” πŸ‘ 18    πŸ” 14    πŸ’¬ 1    πŸ“Œ 3
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Ending publication bias: A values-based approach to surface null and negative results Sharing knowledge is a fundamental principle within the scientific community, yet null and negative results are still being underreported. This Consensus View discusses the problem of such publication...

Null & negative results β‰  failure. They’re essentialβ€”but still sidelined.

Proud to co-author this @plosbiology.org paper tackling systemic bias & calling for culture change.

ECRs pay the highest price for this biased culture!

Blog by @scurry.bsky.social tinyurl.com/ysc23wrx

#PublicationBias

25.09.2025 09:37 β€” πŸ‘ 30    πŸ” 11    πŸ’¬ 0    πŸ“Œ 1

There are currently 11 acting Institute and Center directors at NIH and this will add another. Two more and the majority of these positions will be vacant.

02.09.2025 18:46 β€” πŸ‘ 58    πŸ” 30    πŸ’¬ 3    πŸ“Œ 0

This is an awesome primer for peer review and also a helpful guide to get people thinking about the quality of their own experimental design!

Kudos to the authors!

18.08.2025 18:50 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Congrats @federicamosti.bsky.social and @debbysilver.bsky.social lab! I’m excited to read it!!

11.08.2025 23:53 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

I am honored to be selected as an ASCB fellow! SO much thanks to those who nominated me and provided letters of support!

And congratulations to the other Fellows selected! πŸŽ‰πŸ₯³πŸŽŠ

07.08.2025 16:24 β€” πŸ‘ 202    πŸ” 24    πŸ’¬ 52    πŸ“Œ 0
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Full Committee Markup of Defense and Labor, Health and Human Services, and Education Appropriations Acts | United States Senate Committee on Appropriations United States Senate Committee on Appropriations

πŸ§ͺ Senate appropriators say: NIH's budget gets a... boost!

Rather than 40% cut, NIH gets a $400M *increase* in the Senate committee bill for FY26 (about +1%).

"Congress has your back," said @murray.senate.gov.

ADVOCACY MATTERS! There's still a long road (esp in the House), so keep up pressure.

31.07.2025 13:54 β€” πŸ‘ 266    πŸ” 82    πŸ’¬ 12    πŸ“Œ 14
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R4E community members awarded NIH NINDS METER Grant! β€” R4E R4E community members Drs. Nafisa Jadavji (PI), Nele Haelterman, Michael Malek-Ahmadi and Mrs. Sue McClatchy have been awarded an NIH NINDS METER grant titled β€˜Educating Biomedical Researchers on ...

Read more here: www.repro4everyone.org/blog/p5zqp5d...
Looking forward to getting started! @comm4rigor.bsky.social NINDS Office of Research Quality @mariahhoye.bsky.social

25.07.2025 12:14 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
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Promoting Open Discussions of Scientific Failure within the Annual Society for Neuroscience Conference <p>Join this interactive session as Megan Hagenauer and Daniela Schiller discuss their paper, &ldquo;<a href="https://doi.org/10.1523/ENEURO.0524-24.2024">Promoting Open Discussions of Scientific Fail...

🧠 Tomorrow (6/24: 12-1) I will be doing an interactive webinar with Christophe Bernard and Daniela Schiller to discuss our paper, β€œPromoting Open Discussions of Scientific Failure within the Annual Society for Neuroscience Conference”. Come join & submit questions!
neuronline.sfn.org/scientific-r...

23.06.2025 13:35 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
PA-25-422: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) PA-25-422. NI...

the reissued NOFO for the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) is finally published! grants.nih.gov/grants/guide...

13.06.2025 17:33 β€” πŸ‘ 34    πŸ” 28    πŸ’¬ 2    πŸ“Œ 3

Also be sure to read the instructions a Forms I SF424. These Fs will have the new format/review instructions so there are different components from the previous NOFOs.

13.06.2025 20:03 β€” πŸ‘ 13    πŸ” 12    πŸ’¬ 0    πŸ“Œ 0

And I would take issue if a study with null outcomes was written up to say β€œthis proves the null hypothesis”, etc, but rigorously-conducted null studies are important contributions to a body of scientific evidence.

I really like how this paper lays it out: elifesciences.org/articles/21451

13.06.2025 16:44 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Promoting Open Discussions of Scientific Failure within the Annual Society for Neuroscience Conference The annual Society for Neuroscience (SfN) meeting is a bonanza of scientific achievement: famous keynote speakers, beautiful scientific results, and award ceremonies. This focus is exciting and invigo...

What happens when scientists discuss mistakes they've made?

Here's a lovely paper about developing of a conference series normalizing errors ("Oh Sh*t: Great Scientists Tell Stories About Their Greatest Failures").

#stats #neuroscience #metascience #neuroskyence

tinyurl.com/5n96e5em

07.04.2025 14:56 β€” πŸ‘ 14    πŸ” 5    πŸ’¬ 1    πŸ“Œ 1

I love this paper too!

The author, Rick Born, is part of the @comm4rigor.bsky.social which is developing educational units on topics like confirmation bias!

For anyone interested in learning more, check out the beta form of the unit at c4r.io (and give us feedback so we can keep improving it)!

13.06.2025 13:37 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1

Also no πŸ˜…

But I take your point. I think the issue in my field (molecular/cellular neuroscience) and many others is that numerous studies have shown that we apply more scrutiny to studies with null outcomes than positive ones, even when you condition on experimental design (sample size, etc).

13.06.2025 13:06 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

What does a 40% NIH budget cut mean for funding chances (now ~15%)?

You might think β€œ60% of the money left = 9% success”

❌ NOPE!!!

1-3%

because 80% of the budget is for existing grants

New science? Starved
Ongoing grants? Slashed 😒

#FundingScienceSavesLives

11.06.2025 23:37 β€” πŸ‘ 40    πŸ” 23    πŸ’¬ 0    πŸ“Œ 2

If you are a current or former NIHer and want to be in this starter pack, please comment below for an add.

22.05.2025 22:50 β€” πŸ‘ 16    πŸ” 7    πŸ’¬ 6    πŸ“Œ 2

Please add me- I’m a program manager in the NINDS Office of Research Quality! Thanks!

12.06.2025 00:13 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

I wish I’d been taught that publishing rigorously conducted null studies is actually essential for the health of science and the extra scrutiny we give to studies with null outcomes stems from unconscious bias.

pubmed.ncbi.nlm.nih.gov/18199864/

pubmed.ncbi.nlm.nih.gov/21098355/

11.06.2025 13:20 β€” πŸ‘ 9    πŸ” 5    πŸ’¬ 2    πŸ“Œ 0

Let’s talk rigor.
What’s ONE thing you wish you’d been taught earlier about study design, statistical analysis, or data reporting?
Drop your lessons & tips for the new generation πŸ‘‡

#GradSchoolAdvice #RigorInResearch c4r.io

11.06.2025 12:03 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 1    πŸ“Œ 1

DEADLINE TODAY!!

Submissions close at 11:59 pm EDT!

Unlike a grant, the submission is relatively short- just six short prompts of ~200-350 words each!

There’s still time to submit an entry!

www.challenge.gov?challenge=ni... Challenge.gov

06.06.2025 12:46 β€” πŸ‘ 1    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Challenge.gov Challenge.gov is the official government website supporting prize challenges and prize competitions that are sponsored by the US federal government. Here federal agencies provide prize awards to publi...

NINDS Early-Career Rigor Champions Prize- DEADLINE 6/6/25!
To recognize and reward individuals and small teams of early-career scientists who are promoting enhanced research rigor!

$10,000, $5,000, and $2,500 prizes

www.challenge.gov?challenge=ni...

04.06.2025 13:44 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

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