Danielle Beckman

Confocal microscopy image showing neurons and microglia

Original image from the microscope

Analyzing how neurons🔵 and microglia🟡 (brain immune cells) interact and I vote for 3D microscopy videos with appropriate soundtracks 🤘 👩‍🎤🔬 #FluorescenceFriday

"Analyses of cancer survivors databases reveal that SARS-CoV-2 infection substantially increases the risk of cancer-related mortality and lung metastasis compared with uninfected cancer survivors."

Mice data show #COVID drives the proliferation of previously dormant cancer cells.

Long COVID Changes Neuroscientist’s Career Trajectory. In 2021, neuroscientist Janna Moen, PhD, was studying the molecular mechanisms that drive addiction as a post-doctoral researcher in New York City. She was eager to complete her program and advance the understanding of substance abuse disorders. Then she started to experience increasingly concerning physical symptoms, including numbness, burning sensations, and twitching. She also found herself getting tired even after light exertion. “A 20-minute walk to work would be exhausting,” Dr. Moen said. She sought help, and after ruling out a number of conditions, her physician diagnosed her with Long COVID. Dr. Moen traced her illness back to a mild infection with SARS-CoV-2 in 2020. Unfortunately, she contracted COVID again in December 2021. Although the second infection was also mild, afterward her long-term symptoms became even more severe. “I woke up one morning and was completely out of it,” she said. “I couldn’t think straight. After that, I started to subtly decline. I was not able to tolerate most upright activities anymore. I would end up having to lay on the floor in elevators because I didn’t want to pass out. I stopped taking the train, because you never know if there are going to be any places to sit. It was a nightmare.” Dr. Moen could no longer handle the physical demands of her laboratory work, so she made the difficult decision to leave her post-doctoral program. “Basically, I couldn’t keep doing the animal behavioral model work,” she said. Her challenges gave rise to a new interest, however, when she began reviewing COVID-19 research. “It’s very clear that this virus causes a lot of problems for many people,” she said. “That’s what inspired me to switch fields and try to do some of this work myself.” In 2023, Dr. Moen moved to Connecticut to take another post-doctoral position, this time studying neuroimmunology in the Iwasaki Lab at Yale University.

Finally, all my admiration for @jannamoen.bsky.social, the first author of this comprehensive review I wrote about. She is a #LongCovid patient herself and you can read her story here:
css.washingtonpost.com/wellness/202...
and fnih.org/patient-voic...

PCN Frontier Review Open Access Neuroimmune pathophysiology of long COVID

I commend the PCN Journal for highlighting and welcoming studies about #LongCovid; more journals should do the same. You can read the original review by Yale's team @jannamoen.bsky.social @bakermind.bsky.social and @virusesimmunity.bsky.social here onlinelibrary.wiley.com/doi/10.1111/...
#NeuroCovid

Beyond brain fog: COVID-19 can leave lasting effects on the brain. Image shows a summary of the key findings observed in autopsy and animal studies investigating how SARS-CoV-2 can impact the body and induce neuroimmune dysregulation. A disruption in how the brain communicates with the body can lead to the development of several complex symptoms, which have been observed in Long Covid patients.

Beyond brain fog: #COVID19 can leave lasting effects on the brain. Honored to be invited to write this editorial for the Journal of the Japanese Society of Psychiatry and Neurology. It relates to @virusesimmunity.bsky.social team's review.You can read it here: onlinelibrary.wiley.com/doi/10.1111/...

Ozzy Osbourne star

The doors star

Quentin Tarantino star

Michael J Fox staaaar

While in LA, went to check my favorite stars 🌟

Hamsters with long COVID present distinct transcriptomic profiles associated with neurodegenerative processes in brainstem - Nature Communications SARS-CoV-2 persists in the brainstem long after the initial infection has passed. Infected animals exhibit symptoms of anxiety, depression, and memory impairment as well as changes in the brain that c...

Read the original study published this week here: www.nature.com/articles/s41...

Hamsters with long COVID present distinct transcriptomic profiles associated with neurodegenerative processes in brainstem

Once we thought it would be nearly impossible to modulate #LongCovid in rodent models, but science is getting there. More evidence for direct #COVID neuroinvasion, viral persistence in the brain , and more explanations for cognitive and psychiatric alterations... #NeuroCovid

Confocal microscopy image showing microglia interacting with neurons accumulating pathological tau protein in Alzheimer's disease

Confocal microscopy image showing microglia interacting with neurons accumulating pathological tau protein in Alzheimer's disease (microglia IBA-1 channel only)

Confocal microscopy image showing microglia interacting with neurons accumulating pathological tau protein in Alzheimer's disease (neurons MAP2 and phospho-tau AT8 channels only)

Neurons on fire 🔥 ? Check how these microglia 🟡 interact with neurons 🔵 accumulating phospho-Tau 🔴, one of the hallmarks in #Alzheimer's disease.
What is happening there? Are these microglia making things better or worse?
#FluorescenceFriday #Neuroinflammation

Vc vai gostar! ❤️

Book by Nancy Baron: Escape from the Ivory Tower: A Guide to Making Your Science Matter

Re-reading this book while waiting for my photos to finish, and thinking it should be a mandatory reading for all scientists, especially students and trainees. #STEMeducation

It's important to notice that 'uninfected' is not a guarantee. Many people who think they have never had COVID, were asymptomatic.

People’s brains aged faster during the COVID pandemic — even the uninfected Study of nearly 1,000 people showed that brain ageing was not linked to infection status, but cognitive decline was.

Original study on Nature Comm here: www.nature.com/articles/s41...

Comment on Nature here: www.nature.com/articles/d41...

title of the manuscripts published today

What happens when you compare brain scans from people before and after the pandemic started?
A new study released today with 996 participants shows the pandemic accelerated brain aging for all, but those infected with COVID also presented reduced cognitive performance. #NeuroCovid #LongCovid

Thank you very much Steph! Wishing you a fast recover ❤️

brazil is crazy good this week

LOL, eu tenho vivido só pelos memes. 😅

Neurons in the human cortex.

Neurons in the human cortex.

Just pretty or useful? SMI32 🟡 targets a set of neurons more vulnerable to dementias. NeuN 🔵 identifies most mature neurons in the cortex. Quantifying neurons identified by both markers can give you insights into neurodegenerative processes occurring in the brain
#Neuroscience #FluorescenceFriday

Confocal microscopy photo of the cortex showing neurons and astrocytes

Confocal microscopy photo of the cortex showing neurons and astrocytes

Check out this cool astrocyte multitasking in the brain! It manages a blood vessel on one side while supporting a neuron on the other. Everything in the brain, from blood vessels to neurons, is interconnected! 🔬 🧠
#microscopy #Neuroscience

A person is projecting a text on a big screen that reads: The greatest research skill you can have is being a nosy bitch who wants to find out

Let's be nosy and noisy bitches 🤘🔬

Bird flu? Don’t worry, we fired the scientists he Trump administration’s recent decision to cancel $766 million in funding to vaccine company Moderna for the development of a bird flu vaccine

Bird flu? Don’t worry, we fired the scientists. geneticliteracyproject.org/2025/07/15/b... via @geneticliteracy.bsky.social
#H5N1 #Birdflu

Armond has #LongCovid.
This is his experience.

#CountLongCovid

This is what I am talking about 😁

Confocal microscopy photo of the brain showing pyramidal neurons in the frontal cortex

This is who you REALLY are. You are not a reflection in a mirror. There are no liposuction or fillers to prevent your neurons from showing your actual age.
Support basic scientific research so that one day we may learn how to grow new neurons in the brain.
#FluorescenceFriday

Beautiful, I love videos!

Sharing here that Jamie @followingmybody.bsky.social prepared a google drive of studies about menstruation and COVID (there are a lot of them)! Jamie works with people to chart their cycles and has seen a lot of disruption post COVID infection. #LongCovid #Covid

drive.google.com/drive/folder...

Lula reply:

Thank you ❤️! Indeed @drjengunter.bsky.social is awesome and an inspiration for me and many others!

It was not my intention to exclude anyone. My question is for everyone who menstruates.