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Nicola Osgood

@thebiochemist.bsky.social

PhD student leveraging next-generation gene editing technologies to study functional genomics 🧬🧬🧬🧬🧬🧬🧬🧬🧬🧬🧬 Kenyan born πŸ‡°πŸ‡ͺ | US Marine Veteran πŸ‡ΊπŸ‡Έ Biochemist πŸ”¬| STEM PhD πŸ‘©πŸΌβ€πŸ”¬ Wife πŸ’ | Mother 🩷 Safe space πŸ’™

56 Followers  |  118 Following  |  18 Posts  |  Joined: 15.11.2024  |  1.9816

Latest posts by thebiochemist.bsky.social on Bluesky

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Earth’s First Climate Tipping Point? Fossils Warn What HappensΒ Next The deep-time story of coral reefs shows both the danger of warming seas and the power of resilience Beneath the waves, something irreversible may have...

Is it happening again? 🌊πŸͺΈ
Millions of years ago, coral reefs collapsed as the planet overheated
And now, it’s happening once more.

Fossils reveal both warning and hope: reefs can recover, but only if we slow change enough to let them.
πŸ§ͺ #SciComm

πŸŽ₯ Watch or read:
buff.ly/jlGRYIF

29.10.2025 12:37 β€” πŸ‘ 13    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
Breakthrough Prize-Winning Biochemist on the Deadly Cost of Funding Cuts | Amanpour and Company
YouTube video by Amanpour and Company Breakthrough Prize-Winning Biochemist on the Deadly Cost of Funding Cuts | Amanpour and Company

This is a phenomenal interview given by my PI’s post-doctoral advisor, Professor David Liu. I encourage you all to watch it and share!

The first bit talks about technology that I use in my research and how these technologies are being applied to treat and cure diseases.

youtu.be/8YhJM6zxYDw?...

24.05.2025 02:22 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Precision genome editing and in-cell measurements of oxidative DNA damage repair enable functional and mechanistic characterization of cancer-associated MUTYH variants Abstract. Functional characterization of genetic variants has the potential to advance the field of precision medicine by enhancing the efficacy of current

I am ecstatic to share this work, which involved functional interrogation of MUTYH variants using base editing. I enjoyed working with Dr. Carlos Vasquez on this project and look forward to seeing this expanded for high throughput!
#baseediting #womeninstem πŸ§ͺ

academic.oup.com/nar/article/...

31.03.2025 17:47 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Definitely seems like they’re peddling the supposed β€œDEI incentives” they were vehemently opposed to. The hypocrisy is wild lol

22.02.2025 01:43 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I bet if every β€œblue” state stopped paying federal taxes, Trump would change his tune. That, or he’d send the military in and start a civil war…more likely the latter unfortunately.

22.02.2025 01:35 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Genome editing with programmable base editors in human cells Genome editing has garnered significant attention over the last decade, resulting in a massive expansion of the genome engineering toolbox. Base edito…

πŸ§ͺI am thrilled to share that our work was just published in Methods in Enzymology!

HUGE thank you to all who contributed to this, but especially to my phenomenal co-first author, @natalie-z.bsky.social, and our mentor, Dr. Alexis Komor.
#baseediting #genomeediting #SciSky #AcademicSky

06.02.2025 02:48 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

#AMIA2024 WELCOME TO BLUESKY! πŸ¦‹

I'm so excited to see people finally arrive at the shores of Bluesky!

I want to make sure you stick around so let me give you a guided tour on how to maximize your fun and engagement here! 🧡

12.11.2024 15:02 β€” πŸ‘ 118    πŸ” 19    πŸ’¬ 14    πŸ“Œ 22
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Constant hypocrisy from conservatives is exhausting, but perhaps more exhausting are the mental gymnastics of their supporters.

20.01.2025 16:20 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

This captures what I’ve been thinking, almost exactly.

12.01.2025 16:23 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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You will read countless times today that the LA mayor cut the LA Fire Department's budget by $23 million.

That is a lie.

The budget was actually *increased* by $50 million.

09.01.2025 15:05 β€” πŸ‘ 27238    πŸ” 12013    πŸ’¬ 886    πŸ“Œ 629

Given his recent announcement about pending changes to Facebook, it would appear Mark Zuckerberg has followed Elon Musk’s direction. This poses a new, significant challenge in combatting misinformation.
Frankly, I’m exhausted, so this is incredibly disappointing. Thoughts?

09.01.2025 13:54 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Oh yeah, I could definitely see it being seen as CV padding. Have you found that the articles have different titles for each journal? Or do they all have the same title? I’m now really intrigued by this concept. I never even thought of it as a possibility, I suppose.

20.12.2024 16:48 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Initial thought: not cool; however, maybe it is more of an accessibility thing? Some people have access to certain journals and not others. Some journals are more affordable than others. I’m torn on this one. What are the problems you see with cross publishing? How does it harm (people, science)?

20.12.2024 14:18 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Download/read "Solving Climate Change" as an eBook now. Link below: πŸ§ͺ

14.12.2024 15:25 β€” πŸ‘ 15    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
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I joined 75+ @nobelprize.bsky.social laureates urging US Senators to oppose RFK Jr.'s confirmation as DHHS Secretary. If you’re in a state with GOP senators, PLEASE reach out to them! I’d deeply appreciate it if you amplified this post! πŸ™
www.nytimes.com/2024/12/09/h...

09.12.2024 23:19 β€” πŸ‘ 506    πŸ” 240    πŸ’¬ 14    πŸ“Œ 8

I want men in science to think about this. Think about the biases you have grown up with so much you're probably not even aware you have them. πŸ§ͺ #WomenInSTEM

10.12.2024 02:28 β€” πŸ‘ 553    πŸ” 167    πŸ’¬ 20    πŸ“Œ 5

Phenomenal work - 3 year relapse-free rates moved from 80-85% up to 97.5% in kids with average risk of relapse. This type of leukemia is the leading type of cancer in children. πŸ§ͺ

10.12.2024 03:10 β€” πŸ‘ 29    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

yeah but I'm sure they'll be sooooo concerned about the wages and welfare of working class Americans

07.12.2024 12:38 β€” πŸ‘ 16    πŸ” 4    πŸ’¬ 2    πŸ“Œ 0

Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! πŸ§ͺ

03.12.2024 14:10 β€” πŸ‘ 29778    πŸ” 5050    πŸ’¬ 459    πŸ“Œ 281
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In #NextGenSequencing news, updated the #NGS #specs w/ two upcoming Illumina $ILMN NovaSeqX 25B kits, for 100cycles and 200cycles.
Now the cheapest $/Gb short-read runs are:
(1) NovaSeq X 25B (300 cycles) = $2.22/Gb
(2) NovaSeq X 25B (200 cycles) = $2.72/Gb
(3) NovaSeq X 10B (300 cycles) = $3.54/Gb

03.12.2024 12:20 β€” πŸ‘ 21    πŸ” 5    πŸ’¬ 1    πŸ“Œ 1
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Thread on need to fight for evidence-based policy - a response to Trump's cabinet picks.

Based on new @bmj.com article by me, @martinmckee.bsky.social & @kentbuse.bsky.social

TLDR: Now is the time to stand up for science, not appease those in power attacking it

www.bmj.com/content/387/... 1/14

28.11.2024 23:58 β€” πŸ‘ 618    πŸ” 276    πŸ’¬ 17    πŸ“Œ 28

But RFK Jr. wrote on X "The main problem with hydroxychloroquine was that it is a generic drug with little profit potential. " When in fact, the main problem is that it doesn't work and actually can hurt people.

25.11.2024 17:13 β€” πŸ‘ 122    πŸ” 19    πŸ’¬ 11    πŸ“Œ 9

For those experiencing issues loading the graph on mobile, open the quiz in a browser, not on BlueSky, and rotate your phone.

25.11.2024 13:47 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I agree that the computer question was poorly worded. You could’ve observed that the computer was running out of memory πŸ€·πŸΌβ€β™€οΈ I opted for β€œhypothesis” because the question stated β€œone possible explanation” which to me is the essence of a hypothesis. But that was definitely a tricky one…

25.11.2024 13:45 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Phew! Was going to quit my PhD if I failed this one…

25.11.2024 13:40 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Interesting…

25.11.2024 00:16 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

This is useful!!

24.11.2024 20:16 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Food access in formerly redlined neighborhoods tied to poor cardiometabolic health CHICAGO — People living in historically redlined neighborhoods with poor access to healthy foods were more likely to have type 2 diabetes, hypertension, coronary heart disease and obesity, resea...

A recent AHA scientific session linked redlined areas with poor food access to higher rates of type 2 diabetes, heart disease, hypertension, and obesity. Improving food access could address these disparities. 🩺 πŸ›Ÿ

20.11.2024 19:20 β€” πŸ‘ 8    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
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Scientists to follow Join the conversation

Great to see so many new people here! Explore Starter Packs to get started!
I made one of scientists with a focus on #ChemBio, #Chemistry, (Chemical) #Proteomics and #DrugDiscovery:
bsky.app/starter-pac...

As well as a short version of the 25 most recommended accounts: bsky.app/starter-pac...
(1/8)

18.11.2024 13:38 β€” πŸ‘ 24    πŸ” 9    πŸ’¬ 1    πŸ“Œ 0
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⚠️THREAD OF ALL SCIENCE-RELATED STARTER PACKS! ⚠️

πŸ”„Share to help people finding its topic/field

- STRUCTURAL BIOLOGY

Structural Biology 1: bsky.app/starter-pack...
Structural Biology 2: bsky.app/starter-pack...
Crystallography: bsky.app/starter-pack...
Synchrotron&CryoEM: bsky.app/starter-pack...

17.11.2024 18:48 β€” πŸ‘ 288    πŸ” 180    πŸ’¬ 39    πŸ“Œ 20

@thebiochemist is following 20 prominent accounts