Siavash Moghadami

Conservationist Jane Goodall, whose work revolutionized the study of primates, has died | CNN Jane Goodall, whose lifelong work as a primatologist helped broaden the world’s understanding of animal behavior and emotions, has died, her institute said Wednesday. She was 91.

Such a tremendous loss for biology. I remember seeing her photos with primates in my biology textbooks and wondering how joyful science could be—and what true passion really means

www.cnn.com/2025/10/01/e...

#AlzheimersDay reminds us why we go to the lab every day. Thanks to the incredible opportunities and support this country provides, we have the chance to turn research into real treatments. In the U.S., science can truly serve people — and that mission must always come before fame or money. 🇺🇸🧠✨

And that’s why “Virtual Cell” needs more real data and less hype!

A brain center that controls consummatory responses The BNST brain region integrates a broad range of external and internal signals to flexibly regulate consumption, revealing a unified control over consummatory responses.

Discovery of a brain center (BNST) that controls consumption (including sweets, fats, salt and other foods) in mice
www.cell.com/cell/fulltex...

Maybe @science.org should be more careful?! Richard Feynman doesn't have two Nobel prizes😟

www.science.org/content/arti...

Great perspective by @dereklowe.bsky.social on recent advances in cell surface #glycoRNA biology, including new work from @raflynn5.bsky.social and collaborators identifying an immune silencing effect of N-glycans on activation of TLRs by Acp3U-RNA (www.nature.com/articles/s41...)

David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87

Such a loss! Thanks for all your contribution to help us better understand the world of biology!

David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87 www.nytimes.com/2025/09/07/s...

So cute!

2022 Nobel Prize winner in Chemistry, #Stanford Prof. Carolyn Bertozzi, delivered an inspiring lecture on #BioorthogonalChemistry at #PekingUniversity on Aug. 28.

@stanford.edu @carolynbertozzi.bskyverified.social

Spread the word - we at @stanford-chemh.bsky.social are searching to fill a new junior faculty at the interface of molecular and computational science. See link below!

Faculty opening in Cornell Chemistry at the Assistant Professor level in the area of chemical biology, broadly defined! academicjobsonline.org/ajo/jobs/30338 #chemjobs

RNA N-glycosylation enables immune evasion and homeostatic efferocytosis - Nature N-glycans on glycoRNAs prevent innate immune sensing of endogenous small RNAs, and the natural mechanism they use demonstrates how glycoRNAs exist on the cell surface and in the endosomal network with...

Another piece of the #glycoRNA puzzle revealed by @raflynn5.bsky.social and @vijayrathinam.bsky.social!! RNAs with modified base acp3U activate TLR3/7, but not when acp3U is N-glycosylated. This is how cell surface/secreted glycoRNAs avoid stimulating autoimmunity.

www.nature.com/articles/s41...

Cajal’s rendering of a Purkinje neuron found in the human cerebellum captures the beauty and intricacy of this complex cell.

Drawing the mind, one neuron at a time: A 2022 book walks readers through the life and work of Santiago Ramón y Cajal, the Spaniard whom many consider the founder of modern #neuroscience.

Check out the #ScienceBooks Review on #BookLoversDay: scim.ag/3RvHDmQ

Lithium deficiency and the onset of Alzheimer’s disease - Nature Lithium has an essential role in the brain and is deficient early in Alzheimer’s disease, which can be recapitulated in mice and treated with a novel lithium salt that restores the physiological level.

Nature research paper: Lithium deficiency and the onset of Alzheimer’s disease

go.nature.com/4ftdsb2

RNA N-glycosylation enables immune evasion and homeostatic efferocytosis by chemically caging acp3U. Excited to report this work lead by Vinnie @vinnieviruses.bsky.social and in collaboration with @vijayrathinam.bsky.social in @nature.com www.nature.com/articles/s41...

Sweet Disguise: Body Hides RNA With Sugar - UConn Today Now that scientists understand the role of RNA glycosylation in deflecting immune system attention, they can check on whether that strategy is somehow going ...

today.uconn.edu/2025/08/swee... Thanks to @uconnresearch.bsky.social and @kimkrieger.bsky.social for covering our glycoRNA paper @vinnieviruses.bsky.social @raflynn5.bsky.social

Cell's sugar coating mapped at below-nanometre resolution Nature - Super-resolution technique works with off-the-shelf optical microscopes.

Scientists have mapped individual sugar molecules on the surface of cells at a resolution once thought to be impossible for light microscopes

go.nature.com/40I9Ewv

Jennifer Doudna is named 2026 Priestley Medalist The award recognizes the biochemist for discoveries on ribozyme function and CRISPR gene editing, and international science leadership

@acs.org is recognizing Jennifer A. Doudna with the Priestley Medal for her discoveries on ribozyme function, the Dicer RNase enzyme, double-stranded RNA processing, and CRISPR gene editing, along with her impactful international science leadership. cen.acs.org/people/award... #chemsky 🧪

Shoot me a message if you want to meet!

I’ll be in Irvine, CA, from August 18–20, 2025, attending the 2025 Conference “The Changing Brain.” Excited to connect with fellow professionals passionate about neuroscience! If you’re attending or in the area, let’s meet up to discuss the latest advancements in brain science.

Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | NEJM Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of zimisle...

What an amazing time to be a biomedical scientist.

www.nejm.org/doi/abs/10.1...

Extracellular exosomal RNAs are glyco-modified - Nature Cell Biology Sharma, Jiao and colleagues report glycosylation of small RNAs within exosomes and propose a glycosylation-dependent mechanism for RNA targeting into exosomes, which may influence intercellular commun...

More insights into #glycoRNA, this time found within exosomes!

www.nature.com/articles/s41...

Great to see #proudofalumni @nmriley.bsky.social on the @cenmag.bsky.social Talented 12 list! 🎉 🏆 Check out his #glycotime research program:

www.riley-research.com

Great piece on @stanford-chemh.bsky.social Institute Scholar @stanleyqilab.bsky.social’s work toward curing diseases with genome editing innovations #ResearchMatters

PET imaging of antisense oligonucleotide distribution in rat and nonhuman primate brains using click chemistry Intrathecally dosed antisense oligonucleotide distribution can be imaged in rat and nonhuman primate brains using a PET tracer and click chemistry.

Cool application of in vivo bioorthogonal chemistry from Biogen, imaging biodistribution of ASOs in the brain 🤯

www.science.org/doi/10.1126/...

Cell surface RNA biology: new roles for RNA binding proteins Much of our understanding of RNA–protein interactions, and how these interactions shape gene expression and cell state, have come from studies looking…

“Cell surface RNA biology: new roles for RNA binding proteins” Jennifer Porat and I discuss this new cellular topology on which to study RNA–RBP interactions and consider how changes in the csRBPs may drive autoimmune responses. @cp-trendsbiochem.bsky.social www.sciencedirect.com/science/arti...

Scientists recreate brain circuit in lab for first time Research breakthrough promises new treatments for severe pain

Brief overview in @data.ft.com of recent work to build four-part assembloids as a model of the human somatosensory neural pathway

www.ft.com/content/f8d5...

Advancing #glycoRNA imaging with FRET-based detection and expanding the scope of their presentation to extracellular vesicles - interestingly high levels of sialoglycoRNAs on blood EVs can be predictive of having cancer @naturecomms.bsky.social

www.nature.com/articles/s41...

Congratulations @pollyfordyce.bsky.social🎉 Very well-deserved!

Bing Ren Appointed Scientific Director and Chief Executive Officer of the New York Genome Center - March 27, 2025 Read about Bing Ren Appointed Scientific Director and Chief Executive Officer of the New York Genome Center at the New York Genome Center on March 27, 2025

Huge gain for @nygenome.org and @columbiauniversity.bsky.social! I enjoyed learning from such a fantastic scientist during my undergraduate time!

www.nygenome.org/news-events/...