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Cindy Yeh

@ccindyyeh.bsky.social

Computational biologist at GigaGen | PhD from UW Genome Sciences | desert rat from New Mexico | views my own

58 Followers  |  133 Following  |  1 Posts  |  Joined: 04.12.2024  |  1.5489

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High-throughput specificity profiling of antibody libraries using ribosome display and microfluidics Wagner etΒ al. develop PolyMap, a platform that uses ribosome display and single-cell RNA sequencing to screen antibody binding to a library of cell-surface-expressed antigens. Using this system, they map the binding of diverse human donor-derived antibodies to SARS-CoV-2 spike protein variants and further characterize unique clones.

First industry publication! Our team developed a high-throughput pooled assay for specificity profiling of antibodies. I’m super grateful to have had the opportunity to contribute to this project www.cell.com/cell-reports...

18.12.2024 01:37 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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