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Syed Mian

@syedmian.bsky.social

Research fellow @crick.ac.uk #BonemarrowStemCells🩸 #MDS #Cancer #DiseaseModelling #EnvironmentalMinglingMatters #CureForMDS ASH-EHA TRTH2025 Opinions are my own! https://scholar.google.com/citations?user=96tYyXUAAAAJ&hl=en

354 Followers  |  422 Following  |  55 Posts  |  Joined: 15.11.2024  |  2.2216

Latest posts by syedmian.bsky.social on Bluesky

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🚨πŸ”₯LSCN's "Breaking Barriers in Cell Biology Workflows" is on Wed 19th Nov.

Learn groundbreaking discoveries and the newest cutting-edge technology !πŸ‘‡

πŸ”—https://www.eventbrite.co.uk/e/lscn-workshop-breaking-barriers-in-cell-biology-workflows-tickets-1600912605699?aff=oddtdtcreator

17.11.2025 11:16 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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World AIDS Day 2025: Living with HIV Join us Tue 2 Dec for World AIDS Day. A warm welcome to all β€” public, researchers, clinicians & anyone curious about HIV/AIDS & science.

We welcome anyone interested in HIV research to join our free annual event marking World AIDS Day.

We’ll hear from expert speakers including Julie Fox, Kevin McKenna and Robin Shattock as they discuss HIV research, clinical trials, policy and activism.

www.eventbrite.co.uk/e/world-aids...

13.11.2025 09:35 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Promotional image for 'Can We Repair the Ageing Brain?' with five speakers and microphones.

Promotional image for 'Can We Repair the Ageing Brain?' with five speakers and microphones.

Why is it so difficult to understand and treat the diseases that cause dementia?

Join our expert panellists as they answer audience questions about Alzheimer's disease, dementia and the ageing brain.

Listen now on your favourite podcast platform: lnk.to/AQOSDementiaBB

12.11.2025 14:38 β€” πŸ‘ 9    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0
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Pressure to publish is rising as research time shrinks, finds survey of scientists Researchers feel that pressures to publish are increasing, but the time and resources available to do research are decreasing, according to a survey by Elsevier.

Scientists feel that the pressure to publish is rising, but that the time and resources they have to do the necessary research are falling, according to a survey of 3,200 researchers

go.nature.com/4hNDvuN

07.11.2025 12:33 β€” πŸ‘ 65    πŸ” 29    πŸ’¬ 0    πŸ“Œ 8
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Doctoral clinical fellows The Crick's clinical PhD programme.

Just a few weeks left to apply for our clinical PhD programme.

We're looking for clinicians who are passionate about research to join the 3-year fully funded programme.

Learn more and see what positions are available ⬇️

www.crick.ac.uk/careers-and-...

30.10.2025 09:41 β€” πŸ‘ 4    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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Doctoral clinical fellows The Crick's clinical PhD programme.

We're looking for clinicians who are passionate about research to join our 3-year fully funded clinical PhD programme. πŸ”¬πŸ©Ί

Apply by 14 November 2025. πŸ‘‡

www.crick.ac.uk/careers-stud...

01.10.2025 08:37 β€” πŸ‘ 13    πŸ” 11    πŸ’¬ 0    πŸ“Œ 5

We all must take the responsibility and don’t just complaint about these problems. Take action and don’t be a spectator!

29.09.2025 15:02 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Medicine at the Crick New insights and breakthroughs in autoimmunity

Book now for our next #MedicineAtTheCrick event, where researchers and clinicians will explore new insights and breakthroughs in autoimmunity.

🎀 Hosted by @dr-james-lee.bsky.social and @carovinuesa.bsky.social
πŸ“… Thursday 20 November

www.eventbrite.co.uk/e/medicine-a...

22.09.2025 10:22 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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The weakest link: how cells use electricity to eliminate their neighbours to maintain healthy barriers Researchers at the Francis Crick Institute and King’s College London have uncovered a surprising role for electricity in keeping our body’s protective cell layers healthy, which could potentially prot...

Researchers at the Crick and @kingscollegelondon.bsky.social have discovered that our epithelial cells, which form protective barriers around our organs, use electricity as a way to maintain these protective layers and prevent overcrowding.

www.crick.ac.uk/news/2025-09...

11.09.2025 13:39 β€” πŸ‘ 13    πŸ” 1    πŸ’¬ 2    πŸ“Œ 2
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Edith Heard life lessons Edith Heard, the Crick’s new Director and CEO, shares ten lessons from a life in science, spanning curiosity, courage, coffee, and the secrets of our genetic code.

Edith Heard our new CEO shares ten lessons from her life in science, from curiosity, courage and coffee to the secrets of our genetic code.

www.crick.ac.uk/news/2025-09...

10.09.2025 13:32 β€” πŸ‘ 49    πŸ” 13    πŸ’¬ 2    πŸ“Œ 0
Screenshot from https://www.preprints.org/manuscript/202507.2155/v1 showing the title of the paper with the word Withdrawn marked in red. Full text visible in the screenshot:

"This preprint has been withdrawn
Preprint - Article - This version is not peer-reviewed.

Withdrawn: Synthetic mRNA Vaccines and Transcriptomic Dysregulation: Evidence from New-Onset Adverse Events and Cancers Post-Vaccination
Natalia von Ranke,Wei Zhang,Philipp Anokin,Nicolas Hulscher,Kevin J. McKernan,Peter A. McCullough,John A. Catanzaro  *

Withdrawal Statement
This preprint has unresolved ethical issues."

Screenshot from https://www.preprints.org/manuscript/202507.2155/v1 showing the title of the paper with the word Withdrawn marked in red. Full text visible in the screenshot: "This preprint has been withdrawn Preprint - Article - This version is not peer-reviewed. Withdrawn: Synthetic mRNA Vaccines and Transcriptomic Dysregulation: Evidence from New-Onset Adverse Events and Cancers Post-Vaccination Natalia von Ranke,Wei Zhang,Philipp Anokin,Nicolas Hulscher,Kevin J. McKernan,Peter A. McCullough,John A. Catanzaro * Withdrawal Statement This preprint has unresolved ethical issues."

Preprint claiming link between COVID-19 mRNA vaccines and 'transcriptomic dysregulation'/cancer (based on just 10 people who got cancer in the year after vaccination) has been withdrawn.

HT: @reeserichardson.bsky.social

preprints.org/manuscript/2...
See: scienceintegritydigest.com/2025/07/25/p...

11.09.2025 17:50 β€” πŸ‘ 369    πŸ” 80    πŸ’¬ 12    πŸ“Œ 7
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Vaccines don't cause autism. What does? Scientists say most brain changes that contribute to autistic traits occur before birth.

Vaccines don't cause autism. What does? Mostly genes.
The number of people diagnosed with autism as screening has improved and the definition of autism has been expanded.
www.nbcnews.com/health/healt...

05.09.2025 20:31 β€” πŸ‘ 3693    πŸ” 1087    πŸ’¬ 183    πŸ“Œ 57
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Mesenchymal stromal cells from JAK2V617F myeloproliferative neoplasms support healthy and malignant hematopoiesis in a humanized scaffold model in vivo Myeloproliferative Neoplasms (MPN) are malignancies of hematopoietic stem and progenitor cells (HSPCs) that lead to the overproduction of mature blood cells. These disorders include Essential Thrombo....

Humanized MPN xenograft model that offers valuable insights into how human BM MSCs interact with JAK2V617F mutant clone.

onlinelibrary.wiley.com/doi/10.1002/... @hemasphere-journal.bsky.social

23.08.2025 11:53 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Team Leader – Genomics Core Facility and Method Development Are you ready to lead a cutting-edge Genomics Core facility while developing state of the art genomics methods? Join us at EMBL! We are seeking talented scientists to develop and lead a cutting-edge G...

Open Team Leader position @embl.org to head & reshape our Genomics Core facility. Interested in providing & developing state-of-the art omics tech to a wide community? A very vibrant, dynamic place to work with fantastic colleagues. Closing Sept 30th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

11.08.2025 09:54 β€” πŸ‘ 23    πŸ” 25    πŸ’¬ 0    πŸ“Œ 1
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HemaSphere Podcast Medicine Podcast Β· Updated Monthly Β· HemaSphere is the official online, open access journal of the European Hematology Association (EHA). HemaSphere publishes exciting basic, translational, and clinic...

So the latest @hemasphere-journal.bsky.social Podcast is out! This time all about Metabolism. You can subscribe podcasts.apple.com/au/podcast/h... to get all the podcasts direct into your feed. Each is around 30 min, perfect for that commute to work.

01.08.2025 05:01 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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Biggest trial of four-day work week finds workers are happier and feel just as productive Compressing five days of work into four can create stress, but the benefits outweigh the downsides, sprawling study shows.

I wonder if this will work for lab based scientific research www.nature.com/articles/d41...

22.07.2025 08:52 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Wellcome Photography Prize exhibition opens at the Crick The Wellcome Photography Prize exhibition opens today at the Francis Crick Institute.

Our free exhibition showcasing the top 25 entries of this year’s Wellcome Photography Prize is now open.

See the winning images and learn more about the exhibition itself, open Wednesday-Saturday until 18 October.

www.crick.ac.uk/news/2025-07...

17.07.2025 14:15 β€” πŸ‘ 8    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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If you want to know about Blood Stem Cell Aging, then THIS is the meeting to go to.
I will be presenting the latest results of the Fraticelli Lab regarding HSC memories and clonal dynamics.

JOIN US !!!!!

ehaweb.org/connect-netw...

11.07.2025 08:43 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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A heterozygous CEBPA mutation disrupting the bZIP domain in a RUNX1 and SRSF2 mutational background causes MDS disease progression - Nature Communications In Myeloiddysplastic syndromes, CEBPA mutations are linked to disease progression and AML. Here, the authors use somatic reprogramming and genome editing to generate isogenic cell lines from an MDS pa...

www.nature.com/articles/s41...

02.07.2025 07:11 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Fetal‐hemoglobin‐expressing red blood cells (β€œF cells”) consist of three distinct types as revealed by single‐cell transcriptomic analysis of circulating reticulocytes Click on the article title to read more.

onlinelibrary.wiley.com/doi/10.1002/...

30.06.2025 18:36 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
A large group of adults and children are engaging in various activities, including some using hula hoops, outside a large building in the sun.

A large group of adults and children are engaging in various activities, including some using hula hoops, outside a large building in the sun.

We’re looking forward to welcoming families to Discovery Day tomorrow πŸŽ‰

It’s going to be a hot and sunny day, so please come prepared with hats, sun cream and water.

Visit the webpage for more information about the day ⬇️
πŸ”— www.crick.ac.uk/whats-on/dis...

20.06.2025 10:46 β€” πŸ‘ 13    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
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Exciting to share the new impact factor of @hemasphere-journal.bsky.social, the #openaccess journal of the European Hematology Association (EHA).
The 2024 Journal Impact Factor is 14.6 - ranking as number 5 of 99 hematology journals (Source: Journal Citations Reports, Clarivate).

18.06.2025 06:07 β€” πŸ‘ 11    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1
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It is a great honor and greater responsibility to take over the chair of the #EHA research committee from Brian Huntly and Ruud Delwel.

Together with Dominique Bonnet I will lead the committee dealing with all aspects of research at #EHA.

15.06.2025 05:00 β€” πŸ‘ 16    πŸ” 1    πŸ’¬ 4    πŸ“Œ 0
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Medicine at the Crick | Pigmentation in health and disease Our Medicine at the Crick event series showcases major advances in biomedical science.

Don’t miss our next free #MedicineAtTheCrick event, happening Thursday 19 June.

We’ve assembled a full programme of expert speakers and panellists to explore the importance of pigmentation in health and disease.

For more information or to book ⬇️
www.eventbrite.co.uk/e/medicine-a...

13.06.2025 13:41 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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5th Crick International Cancer Conference

The deadline for early bird registration for the 5th Crick Cancer Conference has been extended.

See the full programme and book by 15 July to take advantage of reduced ticket rates for early bookers ‡️ www.crick.ac.uk/whats-on/5th...

03.06.2025 16:36 β€” πŸ‘ 7    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Marsupial research reveals how mammalian embryos form Researchers at the Francis Crick Institute have revealed insight into why embryos erase a key epigenetic mark during early development, suggesting this may have evolved to help form a placenta.

Researchers at the Crick have identified a key step in the development of mammalian embryos, shedding light on how mammals have evolved to generate placentas, among other features.

www.crick.ac.uk/news-and-fea...

14.05.2025 15:18 β€” πŸ‘ 14    πŸ” 5    πŸ’¬ 1    πŸ“Œ 1
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Is the UK paying the price for world’s most expensive visas? | The Observer Competing political and economic goals on immigration are resulting in the loss of valuable skills and talent in the UK

As tighter immigration policies are announced today, scientists continue to stress the importance of attracting international talent.

Our director Paul Nurse spoke to the Observer about how this affects science in the UK:

observer.co.uk/news/politic...

12.05.2025 14:18 β€” πŸ‘ 33    πŸ” 22    πŸ’¬ 0    πŸ“Œ 1
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Super excited to be here @MDS2025 in Rotherdam! Looking forward to groundbreaking research and connecting with fellow experts.
First Keynote speaker Prof Della Porta πŸ”₯πŸ₯³

07.05.2025 15:39 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Is the bone marrow microenvironment the hidden catalyst in malignant haematopoiesis? - Leukemia Leukemia - Is the bone marrow microenvironment the hidden catalyst in malignant haematopoiesis?

Excited to share our perspective just out in @leukemia journal! What is bone marrow niche doing in shaping clonal dynamics in MDS and Leukemias.

www.nature.com/articles/s41...

01.05.2025 05:59 β€” πŸ‘ 10    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

One of our latest! We hope you enjoy! Led by @ShoshanaBurke & in collaboration with @OnimaChowdhury πŸŽ‰πŸŽŠ. #MDS #SF3B1 #VitaminB5 #Leukemia

22.04.2025 19:14 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 2    πŸ“Œ 0

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