Additionally, Tsirkas et al. show that R-loops, under specific conditions, can be beneficial for cells, by reducing excessive RNAPII load on highly-transcribing genes, thus preventing potential TRCs.
We are very happy to see this project led by @ioannistsirkas.bsky.social reach the final stages! 🥳
04.08.2025 12:52 — 👍 0 🔁 0 💬 0 📌 0
Such a nice review for one of our latest research works!
04.08.2025 12:44 — 👍 1 🔁 0 💬 0 📌 0
Wishing you all the best as you move on to your next adventure, we are so proud of you! It’s been great having you in the lab — we’ll miss you!
08.04.2025 11:56 — 👍 1 🔁 0 💬 0 📌 0
🚨Paper Alert!
👏 Big congrats to @marcelwerner.bsky.social, ManuelTrauner & rest of @hamperllab.bsky.social team for this brilliant work!
🧬 Check out their amazing research diving into how #TRCs and DOT1L impact genome stability.
A must-read 🧵 for #transcription, #replication & #epigenetics fans👇!
18.03.2025 17:08 — 👍 8 🔁 4 💬 0 📌 1
Thank you, Umberto!
21.02.2025 19:30 — 👍 0 🔁 0 💬 0 📌 0
Happy to hear it, thank you Marcelo!
21.02.2025 19:30 — 👍 0 🔁 0 💬 0 📌 0
Thank you, Daphne!
21.02.2025 19:29 — 👍 1 🔁 0 💬 0 📌 0
Leveraging prior knowledge to infer gene regulatory networks from single-cell RNA-sequencing data | Molecular Systems Biology
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
How can we improve gene regulatory network inference from noisy scRNA-seq data? Our new review in @molsystbiol.org explores the latest methods integrating prior knowledge to enhance reliability. Plus, some suggestions on how to improve benchmarking!
www.embopress.org/doi/full/10....
12.02.2025 20:05 — 👍 26 🔁 15 💬 2 📌 1
Proud to share our latest publication in @narjournal.bsky.social! A fantastic team effort led by @marcelwerner.bsky.social and Manuel T., where we explore the chromatin dynamics at transcription-replication conflicts (TRC) sites and their impact on genome stability using a novel TRC reporter system.
20.02.2025 15:35 — 👍 21 🔁 5 💬 3 📌 0
Best first bsky post posible 4us:
2025 INTERNSHIP CALL IS NOW OPEN!
Ready for an adventure this summer?
Join our 2025 #Epigenetics #SummerInternship at Helmholtz Munich! Dive into AI, stem cells, nutrition and cutting-edge research, while gaining hands-on experience.
Apply now! 👉 bit.ly/40g1BWL
15.01.2025 14:18 — 👍 19 🔁 15 💬 3 📌 1
European Research Council, set up by the EU, funds top researchers of any nationality, helping them pursue great ideas at the frontiers of knowledge. #HorizonEU
The IMP is a leading life science centre in Europe with 220 researchers from 40 countries. Part of the ViennaBioCenter.
Non-profit research and educational institution at the forefront of molecular biology, cancer, neuroscience, plant biology, and genetics.
https://www.cshl.edu/
One of the world’s leading comprehensive cancer centers. To make an appointment: 833-637-6698
We explore cell fate and plasticity - to bridge the gap between basic research and clinical application @lmumuenchen.bsky.social (LMU), Germany. #cell #biology #biomedical #science / Impressum: http://tinyurl.com/59k5d95t
https://www.med.lmu.de/bmc/en
The European Molecular Biology Laboratory drives visionary basic research and technology development in the life sciences. www.embl.org
EMBL's European Bioinformatics Institute (EMBL-EBI) provides open biological data resources and tools, and performs basic research in computational biology. https://www.ebi.ac.uk/
International research centre devoted to curing #cancer and other diseases linked to #aging. @cerca.cat center, member of @bist.eu.
www.irbbarcelona.org
Italy's research institute for #LifeSciences based in Palazzo Italia, Milan. Our mission is to improve human life & technology.
Scripps Research is one of the world's largest, private, non-profit biomedical research organizations. We are Science Changing Life.
IMBA - Institute of Molecular Biotechnology: a leading research institute in Europe, focusing on functional genetics, RNA biology, and stem cell research.
GMI is the only international center for basic plant research in Austria. Research covers many aspects of molecular and evolutionary genetics.
How do cells form tissues? Our research program spans the scales from molecules to organisms. News from the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) in Dresden, Germany. Impressum: https://www.mpi-cbg.de/impressum
As the only "marine" institute within the Max Planck Society, we do basic research in order to better understand microbial life in the oceans and its impacts the environment.
The Max Planck Institute for Molecular Genetics in Berlin. We want to understand how the genome works and how it is regulated, especially during embryonic development & disease. Imprint: https://www.molgen.mpg.de/impressum
An interdisciplinary research institution that conducts basic research in two key areas of modern biology: Immunobiology & Epigenetics in #Freiburg, Germany
https://www.ie-freiburg.mpg.de
This is the Tübingen research campus of the Max Planck Society in Germany. We do basic research in fields of biology, neuroscience, and AI.
For Institute specific updates follow:
@mpicybernetics.bsky.social
@mpi-bio-fml.bsky.social
A multidisciplinary community of researchers with the mission to better understand the roots of disease and narrow the gap between new biological insights and impact for patients. Broadinstitute.org
We are a world leader in genomics research. We apply and explore genomic technologies to advance the understanding of biology and improve health 🧬
https://www.sanger.ac.uk/
We're the Crick, a biomedical research lab in London working to figure out how life works.
Home to more than 2,000 scientists and a free public exhibition space.
https://www.crick.ac.uk/
