@impvienna.bsky.social
The IMP is a leading life science centre in Europe with 220 researchers from 40 countries. Part of the ViennaBioCenter.
Sven Klumpe, joint Group Leader at the IMP and IMBA has received a grant by the Chan Zuckerberg Initiativeโs Biohub to support fibsem-os, an open-source software platform for focused ion beamโscanning electron microscopy.
Read more ๐ https://imba.science/4tiwEP9
@maxperutzlabs.ac.at, @viennabiocenter.bsky.social
02.02.2026 13:15 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0https://www.imp.ac.at/achievements/research-milestones/alipasha-vaziri-neuronalactivity
02.02.2026 13:05 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0
๐ฌ Our Research Milestones essays are back!
This feature highlights Alipasha Vaziri, former Group Leader at the IMP and Max Perutz Labs.
At the IMP, he developed imaging technologies that enabled large-scale recording of neuronal activity at single-cell resolution:
Paper alert! ๐ข How do cells fight viruses without harming themselves? ๐งฌ In @natcomms.nature.com, the @versteegga.bsky.social lab uncover a previously unknown safeguard that keeps DNA-mutating antiviral enzymes in check, protecting the genome while preserving antiviral defense โก๏ธ tinyurl.com/4xbxz9e8
30.01.2026 11:05 โ ๐ 20 ๐ 8 ๐ฌ 2 ๐ 1
Apply to the technical assistant position at IMBA, IMP, and GMI: https://www.oeaw.ac.at/imba/career-education/open-positions/pos2601-technical-assistant
#research #jobs #europe #biology
We are hiring! Join our Sterile Processing Unit as a technical assistant and provide scientists at the IMP, IMBA, and GMI with sterile laboratory glass and plastic goods.
30.01.2026 10:05 โ ๐ 4 ๐ 5 ๐ฌ 1 ๐ 0
https://rupress.org/jem/article/223/3/e20250594/281445/In-vivo-CRISPR-Cas9-screens-identify-new
29.01.2026 08:20 โ ๐ 3 ๐ 1 ๐ฌ 1 ๐ 0Meinrad Busslinger at the IMP have now developed a new CRISPR screening strategy that allows gene function to be studied directly in immune cells inside living mice.
Using this approach, the team identified dozens of previously unknown genes that control plasma cell formation. Beyond new insights
Plasma cells are the immune systemโs antibody factories, producing the molecules that protect us after infection or vaccination. They originate from B cell. Yet how B cells make the switch to become plasma cellsโand which genes control this transitionโisnโt known.
Researchers from the lab of
Plasma cells are the immune systemโs antibody factories, and they originate from B-cells.
Researchers from our Busslinger lab developed a new CRISPR screening method to find the genes that control this transition inside living mice:
More: www.imp.ac.at/news/article...
@viennabiocenter.bsky.social, @haselbachlab.bsky.social, @lgrundmann.bsky.social
New work from our Haselbach lab with collaborators captures ribosomes ๐ฎ๐ช๐ฅ-๐ฃ๐ถ๐ช๐ญ๐ฅ and reveals a flexible, modular strategy behind their assembly, rather than a strict assembly line.
Published in _Nucleic Acids Research _๐ https://doi.org/10.1093/nar/gkag036
Check out our new paper in @natcomms.nature.com .com where we used #cryoEM together with biochemical and mutational analyses investigated the cotranslational protein folding by Ssb in yeast.
Publication: doi.org/10.1038/s41467-025-67685-6
Check below for the cryoEM centric feed. ๐
BLOC-1 and BORC help move and position lysosomes inside cells. New work from the Haselbach and Clausen labs shows they are not uniform complexes, but families of related protein assemblies. Published in PNAS: https://www.pnas.org/doi/10.1073/pnas.2515691123
21.01.2026 09:35 โ ๐ 9 ๐ 4 ๐ฌ 1 ๐ 1
๐งชScientists from our Haselbach lab captured how proteins begin to fold as theyโre being made.
Using cryo-EM, they visualised chaperones guiding nascent proteins on the ribosome: https://www.nature.com/articles/s41467-025-67685-6
SY-Stem 2026 brings two outstanding keynote speakers to the Vienna BioCenter. SY-Stem is a symposium focusing on the next generation of stem cell researchers, organized by the @impvienna.bsky.social & @imbavienna.bsky.social
March 11-13, 2026
Program and registration: www.sy-stem.org
Not that long ago, in vivo mouse enhancer design was a dream. Today, it's a reality! Using transfer deep learning to design de novo synthetic embryonic enhancers active in the heart, limb, and CNS. Great collab with @alex-stark.bsky.social lab! @ucibiosci.bsky.social @impvienna.bsky.social
24.12.2025 15:51 โ ๐ 76 ๐ 23 ๐ฌ 3 ๐ 0
Activator-promoter compatibility in mammals - Hcfc1 is a key and intrinsically CGI-promoter-specific co-activator that cannot activate non-CGI promoters. Lead by @nemcko.bsky.social & Kevin Sabath in collab. with @plaschkalab.bsky.social @impvienna.bsky.social www.biorxiv.org/content/10.6... (1/2)
30.12.2025 08:01 โ ๐ 78 ๐ 23 ๐ฌ 1 ๐ 1https://www.imp.ac.at/news/article/eji-ita-askonas-prize-for-anna-obenauf
19.12.2025 13:40 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0
Congratulations to our Anna Obenauf, Senior Group Leader at the IMP, for receiving the EJI Ita Askonas Prize 2025 for her pioneering work uncovering how cancer evolution, therapy resistance, and immune evasion are intertwined.
โก๏ธ
https://www.imp.ac.at/news/article/fwf-grants-for-moritz-gaidt-and-joris-van-der-veeken
17.12.2025 15:24 โ ๐ 2 ๐ 0 ๐ฌ 1 ๐ 0
๐ Congrats to IMP group leaders Joris van der Veeken & Moritz Gaidt on receiving FWF Stand-Alone grants! Their projects will explore how gene regulation shapes immune cell identity & function. A 3rd grant supports Manuel Matzinger:
17.12.2025 15:24 โ ๐ 15 ๐ 2 ๐ฌ 1 ๐ 0Register online: www.sy-stem.org.
15.12.2025 09:14 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0
In a new paper in the EMBO Journal, researchers in the Pavri lab and collaborators, show how โgenetic grammarโ affect the rate at which somatic hypermutation, the process by which T cells purposely mutate their DNA to generate evolved antibodies : https://bit.ly/4aHetMg
12.12.2025 15:45 โ ๐ 5 ๐ 1 ๐ฌ 0 ๐ 0
SY-Stem 2026 is here! The symposium focusing on the next generation of stem cell researchers returns to the Vienna BioCenter from 11โ13 March 2026. Register online: sy-stem.org
10.12.2025 16:10 โ ๐ 15 ๐ 8 ๐ฌ 1 ๐ 1https://www.imp.ac.at/news/article/erc-consolidator-grant-for-clemens-plaschka
09.12.2025 14:05 โ ๐ 4 ๐ 1 ๐ฌ 0 ๐ 0
