Frontiers | Musculoskeletal adverse events in dogs receiving bedinvetmab (Librela)
ObjectivesTo conduct a specialist-led disproportionality analysis of musculoskeletal adverse event reports (MSAERs) in dogs treated with bedinvetmab (Librela...
Adding a new data point to the discussion: www.frontiersin.org/journals/vet...
Iโve definitely seen some weird things happen to joints after Librela, but I think itโll be difficult to come up with a causal mechanism to explain such a variety of side effects, or the lack of any in many cases.
10.05.2025 13:59 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0
As someone who used to work on transGENIC mice, seeing all kinds of idiots talk about them for the last few days has beenโฆweird?
07.03.2025 03:48 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0
As a constituent, I am extremely disappointed but not surprised. The idea that you would prioritize your reelection over protecting a marginalized group of CHILDREN is abhorrent.
03.03.2025 18:22 โ ๐ 26 ๐ 0 ๐ฌ 0 ๐ 0
Welp. Time for a primary!
03.03.2025 12:57 โ ๐ 3 ๐ 0 ๐ฌ 6 ๐ 0
Now do student loans
13.02.2025 21:06 โ ๐ 3 ๐ 0 ๐ฌ 0 ๐ 0
Nothing more adorable than a CH kitten going ham over Churu!
11.02.2025 14:41 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0
04.02.2025 01:24 โ ๐ 135 ๐ 19 ๐ฌ 2 ๐ 1
I wasnโt sure how long it would take to get confirmation that nothing good would be coming out of my current student loan situation. Only took 10 days.
31.01.2025 02:21 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0
Good morning!
26.01.2025 13:59 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0
Well this is disappointing.
25.01.2025 17:29 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0
Doomscroll assistant
25.01.2025 14:44 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0
So my work literally getting animals to walk pain-free again is โaggressiveโ (their words), but their โexercisesโ count as rehab?
Also, maybe read the instructions on fitting a Help Em Up harness beforehand so the dog doesnโt end up wearing the butt end on his chest for a month!
24.01.2025 23:29 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0
Here is the veterinary equivalent of that (identifying data removed):
24.01.2025 23:23 โ ๐ 0 ๐ 0 ๐ฌ 1 ๐ 0
They also send you home with a wheelchair but itโs assembled incorrectly and doesnโt fit right.
24.01.2025 13:14 โ ๐ 0 ๐ 0 ๐ฌ 1 ๐ 0
Imagine you had surgery for an acute disc herniation and woke up from surgery paralyzed and incontinent. Instead of starting PT, your surgeon gives you four โexercisesโ to do (one of which is standing), and says if you want you can start more โaggressiveโ rehab in about a month.
WTF, right?
24.01.2025 13:11 โ ๐ 0 ๐ 0 ๐ฌ 1 ๐ 0
Sometimes I think my local veterinary collegeโs neuro department is trolling meโฆ
Will provide more context, but first, a hypothetical:
24.01.2025 13:08 โ ๐ 1 ๐ 0 ๐ฌ 1 ๐ 0
My small act of resistance today: sharing my sticker collection with my coworkers.
21.01.2025 17:25 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0
21.01.2025 02:47 โ ๐ 18 ๐ 2 ๐ฌ 2 ๐ 1
True. But Iโll readily admit to using Librela in my practice, and have had no adverse effects, because itโs never the only thing Iโm doing AND patient selection is important (as well as owner selection).
21.01.2025 01:02 โ ๐ 1 ๐ 0 ๐ฌ 1 ๐ 0
Anyway, if youโre looking to talk more about how messed up #vetmed is right now (along with everything else), give me a follow!
Also Iโm hiring!
20.01.2025 18:07 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0
Ultimately it means slowing down and approaching the discussion about aging from more angles, including exercise, diet, rehab, supplements, and pain management. For example, donโt wait to start Adequan until they have no cartilage left, because itโs not going to help much!
20.01.2025 18:06 โ ๐ 0 ๐ 0 ๐ฌ 2 ๐ 0
I think thereโs still so much we donโt understand about biomechanics and how dogs adapt in response to pain and OA that could explain a lot of the โadverse eventsโ.
20.01.2025 18:02 โ ๐ 0 ๐ 0 ๐ฌ 2 ๐ 0
Testing the waters here with a hot vet med take:
The freak out over Librela is entirely predictable. Clients want a quick fix, GPs donโt have the time or skills to do a thorough MSK or neuro exam. So many of my older patients have undiagnosed neck or back pain that is assumed to be โhipsโ.
20.01.2025 18:00 โ ๐ 4 ๐ 0 ๐ฌ 3 ๐ 0
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