Kevin Blyth

Full text link below to a review article just published in Current Pulmonary Reports on Non-Specific Pleuritis. A key topic for those interested in #mesothelioma evolution.

Well done to first author Mark Neilly and thanks to our co-author and pathology colleague, Craig Dick 👏

rdcu.be/d9Fgg

Great to be in beautiful Edinburgh for the National #Mesothelioma Education Day 2025 🏴󠁧󠁢󠁳󠁣󠁴󠁿

Dr Neil McGlinchey kicking off the meeting in fantastic setting at Royal College of Physicians

Looking forward to this tomorrow ⬇️

National #Mesothelioma Network Education Day

✅ New Management Guideline
🩻 New Staging (TNM 9)
📈 Review of Audit Performance (QPI)

Plus Trials, Interventional Pain, Pleural Nursing & Horizon scanning

…then, dinner with team 🎉🍷

Check out this interview with our #PREDICTMeso PI @kevingblyth.bsky.social discussing #mesothelioma; why it takes so long to develop, and what we at @predict-meso.bsky.social are doing to research and develop new treatments
#MesotheliomaResearch #MesoORIGINS #CancerResearch #EarlyDetection

Lunchtime Live - 23/12/2024 - BBC Sounds News updates from Scotland and beyond, plus all your lunchtime sport, travel and weather.

A few mins of #Mesothelioma chat starts @1251 on BBC Scotland Lunchtime Live👇

Why does meso develop decades after exposure?
What are we doing in @predict-meso.bsky.social to develop new treatments?

@uofglasgow.bsky.social
@cruk-si.bsky.social
@cancerresearchuk.org

www.bbc.co.uk/sounds/play/...

Looking forward to talking #mesothelioma on BBC Scotland Lunchtime Live in a few minutes!

There are now 24 step-by-step guides, explaining how to create these ⬇️ data visualizations with R/ggplot2 - I hope this is a useful resource. Find them all here: joachimgoedhart.github.io/DataViz-prot...

Deadly dust stole my husband: fears grow for asbestos crisis in Scotland's buildings They met as teenagers, married young, raised their family and saved hard for the future.

Article in @heraldscotland.bsky.social this week highlights a sad #mesothelioma story & ongoing research in PREDICT-Meso, IAMMED, Meso-SCAPE & excellent Hansen lab

@predict-meso.bsky.social
@djmurphylab2.bsky.social
@cruk-si.bsky.social

www.heraldscotland.com/news/2477596...

It was great to be part of the BTOG/MesoUK Essential Update meeting this week

Topics included diagnostics, new Rx, CNS roles, legal, pleural

Nice to see 2 current PhD students presenting

🏴󠁧󠁢󠁳󠁣󠁴󠁿 Meso Network (Matt)
🧬 PREDICT-Meso (Mark)

@btog.bsky.social
@mesouk.bsky.social
@uofglasgow.bsky.social

Very proud of Jenny Ferguson - PhD viva passed today! 🎉🥂

Her thesis on stratification of #respiratory disease covered

🫁 STRATIFY trial of #pleural staging in Lung Ca
🔬Predictive Markers in #MPE
🦠 Immune markers of severe #COVID19

🙏 R Bhatnagar, C Church & L Richmond!

@uofglasgow.bsky.social

Graphic featuring logos of NHS and Research for the Future, accompanied by an image of a young woman in a wheelchair using a laptop for an online meeting. This visual illustrates the PREDICT-MESO project, which aims to establish a Patient and Public Involvement and Engagement (PPIE) group. The group will provide valuable input at all stages of mesothelioma research.

🟡 Recruiting now – PREDICT-Meso PPI Group
People affected my mesothelioma to join a new PPI group to advise on all stages of mesothelioma research.
 
Message us or visit our website… www.researchforthefuture.org/studies/predict-meso

The prevalence and prognostic significance of Sarcopenia and Adipopenia in Pleural Mesothelioma Altered body composition is associated with adverse survival in multiple cancers. We determined the prevalence, prognostic significance and clinicopat…

New paper from our group on body composition changes in #mesothelioma during chemo ⬇️

💪 61.5% patients lost muscle
🧈 60.4% patients lost fat
🫁 Extreme thoracic muscle loss & total fat loss independently prognostic

Funded by Asthma+Lung UK

www.sciencedirect.com/science/arti...

Kevin Blyth: management of mesothelioma effusion

🔹IPC vs pleurodesis = equivalent efficacy

For pleurodesis:
🔹 Talc = most effective agent
🔹 Big drain no better than smaller ones
🔹 NSAIDs fine for analgesia (won’t limit pleurodesis)
🔹 Talc slurry as good as poudrage

@dean_fennell: 2L mesothelioma options

👉 (small) subset of non-epithelioid pts do very well with Vin
🟢 Gem+Ramucirumab = ⬆️ PFS
❓ Gem maintenance = ⬆️ PFS, but a bit forgotten
🟢 Platinum rechallenge RR 50%
❓Activity in immuno rechallenge, RR up to 50%

Improve your mesothelioma service by forming a network: the 🏴󠁧󠁢󠁳󠁣󠁴󠁿 experience by Matthew Tate

🟢 ⬆️ data completeness
🟢 ⬇️ non-biopsy cases
🟢 ⬆️ OS in non-epithelioid
🔺 OS benefit not solely due to arrival of immunotherapy

@btog.bsky.social
@mesouk.bsky.social

PREDICT-Meso:
🧐 How does inflammation evolve into malignancy?
🧐 Can we diagnose mesothelioma at pre-malignant stage?

👉 80 institutions, 16 countries
👉 x5 work streams

Fantastic, ambitious, international, multi-faceted project

@btog.bsky.social
@mesouk.bsky.social

Matthew Tate presenting outcomes from the Scottish #Mesothelioma Network

⬆️ Overall Survival in Non-Epi cases
⬆️ Use of Immunotherapy
⬆️ OS in Non-Epi cases not receiving IO

Mesothelioma networks should be developed across the UK

Was that a collective sigh of relief, I heard?

On-call week for me at #QEUH Lots of Flu A! 🦠😷 Felt like every other patient today.

Will be interested to see if the upward trend in last weeks numbers continues publichealthscotland.scot/publications...

24 windows of an advent calendar each with a Christmas themed picture eg snowflakes, a cute fox in a scarf, mittens, and a bobble hat . The title is Merry Respmas Advent Calendar

Can you believe it, it’s almost December! This year we’re excited to bring you a #RespMas advent calendar! Every day we’ll open a window to reveal a paper worth reading! By Christmas we’ll all be on top of our Respiratory game! #medsky #pulmsky #lungsky #RespEd #RespIsBest

Hey Sanjay! Nice to see you on here !

Spatially exploring RNA biology in archival formalin-fixed paraffin-embedded tissues Patho-DBiT enables spatial profiling of a range of RNA species (i.e., mRNA, microRNA, tRNA, splicing isoform, etc.) all at once in clinical formalin-fixed paraffin-embedded tissue with high sensitivit...

This is why we are all in this field…to see, and one day to be able to produce work like this.

Patho-DBiT-seq

www.cell.com/cell/fulltex...

Heading home after a fantastic #BTSWinter2024 Leaving energised and grateful for friends and the opportunity to talk #mesothelioma in the Plenary Scientific Symposium. Also excited for 2025 under our new BTS President!

This morning I presented results of the STRATIFY multi-centre trial of staging thoracoscopy for minimal pleural effusion in lung cancer. The prevalence of occult pleural mets was only 14%, thoracoscopy was safe & altered treatment plans. Paper coming soon! #BTSWinter2024

x.com/UKPleura/sta...

I'm very grateful to Asthma & Lung UK for the early support they provided to our now international #mesothelioma research program. Pump-priming is such an impactful strategy for grant-awarding charities x.com/IanJarroldAL...

Day 2 of #WinterBTS2024 started with a sunny walk in followed by presentation of STRATIFY results (pleural staging of Mini-PE). Next up is #mesothelioma presentation at Plenary Scientific Symposium 😬

Sorry to have missed it! Too many overlapping sessions (a good sign I guess!)

This is starting now at #BTSwinter2024 in Windsor on 5th floor!

For anyone attending the Winter BTS meeting next week, we're having a Meso-ORIGINS study investigators' meeting on Wed 27th Nov. 1230-130pm, Rutherford Room on L4. Come and join if you're involved or just interested! #mesothelioma