Awesome infographic on genetic testing in ADPKD by Neera Dahl, @pranavgarimella.bsky.social and Fouad Chebib www.kidneynews.org/view/journal...
28.07.2025 19:29 β π 56 π 11 π¬ 2 π 0@pranavgarimella.bsky.social
Nephrology I Epidemiology I Biomarkers I Uromodulin I ADPKD I PAD I Powerlifting. CHCF Fellow. All activities = personal opinions.
Awesome infographic on genetic testing in ADPKD by Neera Dahl, @pranavgarimella.bsky.social and Fouad Chebib www.kidneynews.org/view/journal...
28.07.2025 19:29 β π 56 π 11 π¬ 2 π 0Thank you to @pranavgarimella.bsky.social and @kidneyfund.bsky.social for the interview!
04.09.2025 18:42 β π 2 π 1 π¬ 0 π 0Associations of Urine Biomarkers During Ambulatory Acute Kidney Injury With Subsequent Recovery in Kidney Function: Findings From the SPRINT Study
bit.ly/AJKDAscher25
@pranavgarimella.bsky.social
Diagram showing all uric acid lowering therapies MoA Figure 1 Title: Summary of common urate-lowering therapies and their mechanisms of action, Legend: Allopurinol and febuxostat are xanthine oxidase inhibitors, reducing the rate of uric acid production. Rasburicase and pegloticase are recombinant uricases that promote conversion of uric acid to allantoin, which is readily excreted in the urine. Probenecid is a nonspecific inhibitor of URAT1 to a much greater extent than OAT1, OAT3, and GLUT9 with a net effect of uricosuria. Dotinurad is a specific URAT1 inhibitor, inhibiting proximal tubular reabsorption of uric acid thereby promoting uricosuria. UA: uric acid; GLUT: glucose cotransporter; NPT: sodium-dependent phosphate transport protein; ABCG2: ATP-binding cassette subfamily G; OAT: organic anion transporter; URAT: uric acid transporter.
Dotunirab - URAT-1 inhibitor which prevents uric acid reabsorption = uricosuric
Nice commentary from @pranavgarimella.bsky.social & Amy Li in @kireports.bsky.social www.kireports.org/article/S246...
Drugs mostly only available in Japan Department
#NephSky #RheumSky
π¨Should we consider a new approach to enhance prognostication in PKD?
See our editorial on CJASN βοΈπ
@asnkidney.bsky.social
#endPKD @pranavgarimella.bsky.social @ucsdhealthsci.bsky.social
journals.lww.com/cjasn/Fullte...
Happening now, Drs @hswapnil.medsky.social and @jordybc.bsky.social discuss resistant hypertension during day 3 of the @kidneyfund.bsky.social #KidneyActionWeek
Fantastic discussion!
Fascinating read on the ever frustrating topic of publication fees: this paper estimates that between 2019 and 2023 researchers and institutions paid a whopping USD $8.968 billion for their findings to be freely accessible and that costs tripled during that time π°
arxiv.org/abs/2407.16551
@pranavgarimella.bsky.social, Chief Medical Officer of the American Kidney Fund, sat down with Dr. Vasishta Tatapudi of NYU Langone Health for a deep dive into xenotransplantation and what it means for the kidney community. Watch the full interview: bit.ly/4khsp23
28.02.2025 17:25 β π 3 π 1 π¬ 0 π 0AKF Chief Medical Officer @pranavgarimella.bsky.social sat down with @pharmacytimes.bsky.social to discuss the recent FDA approval of semaglutide to reduce kidney disease & cardiovascular death risks in adults with type 2 diabetes & chronic kidney disease. Watch the interview: bit.ly/41sSynb
21.02.2025 16:12 β π 3 π 2 π¬ 0 π 0This is what I am worried about too, Graham. The large volume of patients in CA and especially here as you know who rely on emergency Medi-Cal for dialysis is enormous
21.02.2025 15:16 β π 2 π 2 π¬ 1 π 0Hey #NephSky anyone ever heard of orthotopic kidney transplant (nephrectomy & transplant combined)? Have a patient with a good match living donor but poor femoral vessel targets due to calcium. Been turned down twice for kidney transplant surgery due to calcified vessels.
04.02.2025 17:16 β π 7 π 4 π¬ 1 π 0@gokidgo.bsky.social @ecorneclegall.bsky.social
21.01.2025 15:31 β π 1 π 0 π¬ 0 π 0@edgarvlermamd.bsky.social
21.01.2025 15:29 β π 1 π 0 π¬ 1 π 0Finally, the KDIGO 2025 #ADPKD Guidelines are out.
Whats in it?
β
Genetic screening for persons at risk
β
Best approach to managing cyst infection
β
Considerations for treatment with tolvaptan
β
ADPKD and mental health
All this and much more! www.kidney-international.org/article/S008...
I am happy to announce my appointment as @kidneyfund.bsky.social first Chief Medical Officer! I look forward to lending my clinical expertise to help AKF better serve the 1 in 7 Americans living with kidney disease & joining an organization that fights kidney disease on all fronts.
08.01.2025 16:56 β π 13 π 3 π¬ 3 π 0Hello Blue Sky
05.12.2024 14:41 β π 9 π 1 π¬ 0 π 0