Siawoosh Mohammadi's Avatar

Siawoosh Mohammadi

@siawooshmr.bsky.social

Physicist | MRI, biophysics, microstructure, in/ex vivo histology | Prof. @uniluebeck.bsky.social, PI @UKEhamburg, affiliated @lipmpib.bsky.social, @mpicbs.bsky.social | Views are my own https://www.micromri.uni-luebeck.de/institut

1,774 Followers  |  609 Following  |  85 Posts  |  Joined: 06.10.2023  |  1.9464

Latest posts by siawooshmr.bsky.social on Bluesky

On my way to Marseille - waiting at Munich airport for my flight. Unfortunately, there was (time-wise) no affordable way from Hamburg to Marseille with the train. So, I had to take the flight option. But still, I am looking forward to seeing all my colleague and friends in person at the ESMRMB!

07.10.2025 17:26 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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HippoMaps: multiscale cartography of human hippocampal organization - Nature Methods HippoMaps provides an open-source resource for studying the human hippocampus at different scales and with different modalities such as histology, fMRI, structural MRI and EEG.

HippoMaps: an open-source resource for studying the human hippocampus at different scales and with different modalities.
www.nature.com/articles/s41...
@jordandekraker.bsky.social @borismontreal.bsky.social @jclauneuro.bsky.social @neuroak.bsky.social @sofievalk.bsky.social @donnagift.bsky.social

03.10.2025 12:50 β€” πŸ‘ 22    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0

There are two other speakers taking about qMRI, in the session:
Sebastian WeingΓ€rtner - TU Delft
Title: Quality assessment of quantitative MRI
Amy MCDOWELL - UCL
Title: Use of quantitative MRI in a clinical populations

01.10.2025 09:12 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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And I will give a talk in the session "Quantitative MRI and its confoundings" (Friday, 10/10/25) with the title "Quantitative MRI and its confounding" - I didn't choose the title🀣

01.10.2025 09:11 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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Frank (Francisco J. Fritz) will present his amazing data on our ERC study. The title of his presentation "Quantitative MRI study of excised brain tissue in drug-resistant epilepsy patient: from in-vivo to ex-vivo"

And here is a little teaser

01.10.2025 08:57 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Three of our group from LΓΌbeck will be in Marseille. Laurin Mordhorst will present his final PhD work with the title "Reaching the Tail: Validating MRI Axon
Radius Mapping with MRI-Scale Histology"

01.10.2025 08:51 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

I am looking forward to the meeting!

01.10.2025 08:23 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 1    πŸ“Œ 1
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Judith Schirmer used sodium MRI at 7T to characterize cysts in kidneys using in vivo and ex vivo measurements.

29.09.2025 20:37 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Jan-Malte Oeschger from our group in LΓΌbeck presented our travel-head study on optimising an 1-hour clinical quantitative MRI protocol.

29.09.2025 20:35 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Marc Jonuscheit from DΓΌsseldorf presented his work on 31P-MRS in the liver in tyoe-1 diabetes and controls. They combined T1 and P_i concentration measurements on a clinical MR system.

29.09.2025 20:34 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Federicia Calafiore from Lund presented her amazing results about measuring CSF flow in Normal Pressure Hydrocephalus.

29.09.2025 20:32 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Better late than never!

Here is a little summary of my notes during one of the sessions of the Nordic (@ismrmnordic.bsky.social) and DACH-ISMRM from two weeks ago in Kiel.

29.09.2025 20:31 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 2    πŸ“Œ 0

Congrats Ondrej! Great news.

25.09.2025 06:26 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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🚨 I am over the moon πŸŒ“ to announce that I am joining University College Dublin @ucddublin.bsky.social as an Assistant Professor this fall to start the Uncertain Mind (UMI) lab πŸ’«

I am looking for PhD/Postdoc candidates to join (more below πŸ‘‡ ). Please RT as the deadline is pretty soon πŸ™

24.09.2025 15:18 β€” πŸ‘ 138    πŸ” 37    πŸ’¬ 26    πŸ“Œ 5
GrΓΌnes Demo-Plakat: Oben groß β€žKLIMA DEMOβ€œ, mittig in Weiß das Datum 20.09.. Unten links eine Person im roten Hoodie mit erhobener Faust, in der anderen Hand ein Megafon, aus dem bunte Blumen wachsen. Unten rechts das β€žFridays for Futureβ€œ-Logo mit Erdkugel.

GrΓΌnes Demo-Plakat: Oben groß β€žKLIMA DEMOβ€œ, mittig in Weiß das Datum 20.09.. Unten links eine Person im roten Hoodie mit erhobener Faust, in der anderen Hand ein Megafon, aus dem bunte Blumen wachsen. Unten rechts das β€žFridays for Futureβ€œ-Logo mit Erdkugel.

Am Samstag (!), 20.09.2025 ist wieder Klimademo!

Infos: fridaysforfuture.de/klimastreik/

18.09.2025 07:23 β€” πŸ‘ 34    πŸ” 13    πŸ’¬ 0    πŸ“Œ 1
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Reconstructing long-range axons from dense brain images is tough.

This study introduces a novel method that separates axon identification from global statistical rules, showing big improvements over existing tools for mapping neuronal projections.
buff.ly/OBKr9cM

07.09.2025 10:01 β€” πŸ‘ 23    πŸ” 8    πŸ’¬ 0    πŸ“Œ 1

Our lab is fully supporting the journal (2 papers published, 1 in revision, and more in prep, 2 reviewed - only me). And looking at the published papers in IMAG, it seems like we are not alone. This journal is becoming the new top neuroimaging journal! Thanks to the editor team for making the move!

06.09.2025 07:09 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Launched in 2023, Imaging Neuroscience is now firmly established, with full indexing (PubMed, etc.) and 700 papers to date.

We're very happy to announce that we are able to reduce the APC to $1400.

Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.

05.09.2025 02:59 β€” πŸ‘ 226    πŸ” 79    πŸ’¬ 2    πŸ“Œ 6

I want to do a session on principles of designing scientific figures with my lab. Any recommendation for good online material? #PsychSciSky #neuroskyence #Neuroimaging

03.09.2025 14:22 β€” πŸ‘ 17    πŸ” 4    πŸ’¬ 3    πŸ“Œ 0
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🌟 Mansfield Lecture 2025 🌟
#ESMRMB2025 proudly welcomes Prof. Oliver Speck (University of Magdeburg)!

🎀 Title of the lecture:
"It's the Magnet, stupid!"

One of the highlights of the meeting you definitely don’t want to miss.

πŸ‘‰ You can still register via esmrmmb2025.org

03.09.2025 08:00 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Short-range human cortico-cortical white matter fibers have thinner axons and are less myelinated compared to long-range fibers despite a similar g-ratio by Philip Ruthig, David Edler v.d. Planitz, Maria Morozova, Katja Reimann, Carsten JΓ€ger, Tilo Reinert, Siawoosh Mohammadi, Nikolaus Weiskopf, Evgeniya Kirilina, Markus Morawski The size and complexity of the human brain require optimally sized and myelinated fibers. White matter fibers facilitate fast communication between distant areas, but also connect adjacent cortical regions via short association fibers. The difference in length and packing density of long and short association fibers pose different requirements on their optimal size and degree of myelination. The fundamental questions of (i) how thick the short association fibers are and (ii) how strongly they are myelinated as compared to long fibers, however, remain unanswered. We present a comprehensive two-dimensional transmission electron microscopic analysis of ~400,000 fibers of human white matter regions with long (corpus callosum) and short fibers (superficial white matter). Using a deep learning approach, we demonstrate a substantially higher fiber diameter and higher myelination thickness (both approximately 25% higher) in corpus callosum than in superficial white matter. Surprisingly, we do not find a difference in the ratio between axon diameter and myelin thickness (g-ratio), which is close to the theoretically optimal value of ~0.6 in both areas (0.54). This work reveals a fundamental principle of brain organization that provides a key foundation for understanding the human brain.

Short-range human cortico-cortical white matter fibers have thinner axons and are less myelinated compared to long-range fibers despite a similar g-ratio @PLOSBiology.org

23.08.2025 22:09 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
Arrangement of raw data, semantic, and instance segmentation of human corpus callosum fibers, acquired by transmission electron microscopy. The data used for this image were generated by Maria Morozova, David Edler von der Planitz, and Philip Ruthig. All cover Art was created by the MPI for Human Cognitive and Brain Sciences Graphics department (Andrea Sandmann)

Arrangement of raw data, semantic, and instance segmentation of human corpus callosum fibers, acquired by transmission electron microscopy. The data used for this image were generated by Maria Morozova, David Edler von der Planitz, and Philip Ruthig. All cover Art was created by the MPI for Human Cognitive and Brain Sciences Graphics department (Andrea Sandmann)

#Myelination enables faster signal propagation in the brain, but takes more energy & space. @philipruthig.bsky.social &co reveal how short- & long-range #WhiteMatter fibers differ, showing how these variations affect neural communication & processing efficiency @plosbiology.org πŸ§ͺ plos.io/4mq5tOy

21.08.2025 12:49 β€” πŸ‘ 10    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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How are human brain regions connected? Are the connecting axons thicker and more myelinated the longer these connecting fibers are?

In our recent paper we find that indeed, they are! Read the skeetorial below ⬇️⬇️⬇️

plos.io/4mq5tOy
#neuroscience #neuroskyence #whitematter #deeplearning

21.08.2025 12:38 β€” πŸ‘ 20    πŸ” 12    πŸ’¬ 3    πŸ“Œ 2

That leaves me to thank my excellent co-1st author David Edler von der Planitz, and our collaborators and co-supervisors @siawooshmr.bsky.social, @nikweiskopf.bsky.social, Evgeniya Kirilina, and Markus Morawski!

A collaborative project of @mpicbs.bsky.social and @unileipzig.bsky.social!

21.08.2025 12:38 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Thanks to all (co)authors & reviewers for their contribution to this study on #layer specific changes in #sensory #cortex across the #lifespan in #humans & #mice now out in @natneuro.nature.com Here is a short summary of our findings 1/6

11.08.2025 14:29 β€” πŸ‘ 41    πŸ” 19    πŸ’¬ 1    πŸ“Œ 1
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News from ENIGMA-Epilepsy! 🧠

Our latest study links polygenic risk for TLE-HS to cortical thinning in kidsβ€”mirroring patterns in adult patients.

Early imaging-genetics insights could reveal interplay of epilepsy risk and phenotypes before symptoms emerge.

Read more πŸ‘‰ doi.org/10.1093/brai...

18.08.2025 11:42 β€” πŸ‘ 21    πŸ” 8    πŸ’¬ 0    πŸ“Œ 1
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Kommentar Energiepolitik: Weichen fΓΌr weitere Erdgas-AbhΓ€ngigkeit gestellt

Klar kann Katherina Reiche darauf hoffen, dass CCS Gaskraftwerke klimaneutral macht. Aber vielleicht kommt auch die Zahnfee und zaubert das CO2 einfach weg, das wΓ€re Γ€hnlich realistisch.

Kommentar zur Energiepolitik der BuReg fΓΌr den DLF.
share.deutschlandradio.de/dlf-audiothe...

10.08.2025 05:52 β€” πŸ‘ 1124    πŸ” 356    πŸ’¬ 43    πŸ“Œ 16
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#bignews: @unibonn.bsky.social now has a Centre for Artificial Intelligence and Neuroscience and it is already growing! Welcome to Bonn, Professor Floris de Lange @predictivebrain.bsky.social ! New #caian website and more updates will follow within the next few weeks.

www.caian.uni-bonn.de/en/news

04.08.2025 07:11 β€” πŸ‘ 59    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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New paper in Imaging Neuroscience by Jochen Schmidt, Nikolaus Weiskopf, et al:

High-resolution quantitative T2 mapping of the human brain at 7 T using a multi-echo spin-echo sequence and dictionary-based modeling

doi.org/10.1162/IMAG...

29.07.2025 04:27 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Ultra-high gradient connectomics and microstructure MRI scanner for imaging of human brain circuits across scales Nature Biomedical Engineering - The Connectome 2.0 MRI scanner reconstructs the fine fibres in the human brain and determines cellular and axonal size at an ultra-high resolution.

Ultra-high gradient connectomics and microstructure MRI scanner for imaging of human brain circuits across scales rdcu.be/ewDRc

17.07.2025 16:56 β€” πŸ‘ 7    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1

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