Siawoosh Mohammadi

Isotropic, aberration-corrected light sheet microscopy for rapid high-resolution imaging of cleared tissue - Nature Biotechnology A light-sheet microscope built from off-the-shelf components enables high-resolution clear tissue imaging.

I am happy to share a recent collaboration with @huiskenlab.bsky.social and @aakhte.bsky.social , who developed a great technique for performing fast and, above all, isotropic light-sheet microscopy. www.nature.com/articles/s41...

Mexiko hat gestern ein Klimaziel für 2035 vorgelegt, das von Fachleuten als wirklich ambitioniert bewertet wird #COP30
www.wri.org/news/stateme...

Eine exklusive Forsa-Umfrage für Table.Briefings zeigt: Auch unter CDU/CSU- und SPD-Wählern fordern viele mehr #Klimaschutz. Und selbst in der wirtschaftlich schwierigen Lage soll das deutsche Klimaziel nicht aufgeweicht werden, so die Befragten. 1/3

table.media/climate/them...

Ihr glaubt gar nicht, wie häufig grad in französischen Nachrichten die deutsche Regierung zitiert wird:
Sie taugt stels als Beispiel für den Rückschritt in der Klimapolitik vor der Klimakonferenz:
Schließlich will sie das EU-Verkaufsverbot von neuen Diesel- und Benzin-Autos ab 2035 kippen #rollback

We just published a paper in PNAS, showing microstructural changes to the hippocampus in aging and presymptomatic Alzheimer's disease - in humans, in vivo.

We continue to show the value of structural MRI beyond simply measuring large-scale atrophy!

Read here: ow.ly/1NvV50XkXnX

#neuroscience2025: Come and meet four of us of the @jonasobleser.bsky.social lab and some of our work at Society for Neuroscience San Diego 2025 next week, we will have 4 posters in the TUESDAY PM (1-5 pm) SESSION: @uniluebeck.bsky.social @sarahtune.bsky.social

We wrote a blog post about common misconceptions of basic EPI parameters.

Test your knowledge of EPI myths. layerfmri.com/epimyths/ 1/3

View from your office onto Giessen and surrounding villages.

Please repost! I am looking for a PhD candidate in the area of Computational Cognitive Neuroscience to start in early 2026.

The position is funded as part of the Excellence Cluster "The Adaptive Mind" at @jlugiessen.bsky.social.

Please apply here until Nov 25:
www.uni-giessen.de/de/ueber-uns...

Wow!

By comparing differently tuned glomeruli, this work shows that the brain uses different circuit layouts for specialised vs general smells, offering new insight into how odour meaning is encoded.
buff.ly/XDmo4Ue

Of course most exciting for me: cytoarchitectonic proof that the VIM exists (and is not a subunit of VL as implied by the Jones nomenclature).

Congrats Iyad!

Gosselin et al. observed that sound information is profoundly transformed from the ear to the central brain. This artwork by Wei Li (Institut de l’Audition, Paris) illustrates the complexity of processes underlying these transformations.

How are auditory features represented across the #AuditoryPathway? @bathellierlab.bsky.social show that #auditory feature tuning emerges through a mix of gradual & stepwise changes, with early representation of simple features & later refinement of complex ones @plosbiology.org 🧪 plos.io/4oi0XCY

When #HHMIJanelia released the #Drosophila hemibrain in 2020, rendering all cell types at once with full shading/shadows was too hard, so the video showed them region by region. Technology has since advanced, and I went back and rendered them all together. I like how it shows the internal structure.

Great video. Thanks for sharing.

Great render of the beautiful drosophila hemibrain! 👇

Petition · Wir sind die Töchter und das ist unsere Antwort, Friedrich Merz! #WirSindDieTöchter · innn.it Jetzt innn.it-Petition unterschreiben & Cesy Leonard, Gründerin Radikale Töchter unterstützen!

innn.it/toechter

Data Scientist or Machine Learning / AI expert (m/f/d) Data Scientist or Machine Learning / AI expert (m/f/d) to join the AI and High-Performance Data Analytics division of MPCDF.

We are looking for “Data Scientist or ML/AI expert” who will work at the cutting edge of data science and neuromaging in a collaboration between @mpicbs.bsky.social and the Max Planck Computing and Data Facility (MPCDF).

Deadline: 10th Nov. 2025.

Apply here:

On my way to Marseille - waiting at Munich airport for my flight. Unfortunately, there was (time-wise) no affordable way from Hamburg to Marseille with the train. So, I had to take the flight option. But still, I am looking forward to seeing all my colleague and friends in person at the ESMRMB!

HippoMaps: multiscale cartography of human hippocampal organization - Nature Methods HippoMaps provides an open-source resource for studying the human hippocampus at different scales and with different modalities such as histology, fMRI, structural MRI and EEG.

HippoMaps: an open-source resource for studying the human hippocampus at different scales and with different modalities.
www.nature.com/articles/s41...
@jordandekraker.bsky.social @borismontreal.bsky.social @jclauneuro.bsky.social @neuroak.bsky.social @sofievalk.bsky.social @donnagift.bsky.social

There are two other speakers taking about qMRI, in the session:
Sebastian Weingärtner - TU Delft
Title: Quality assessment of quantitative MRI
Amy MCDOWELL - UCL
Title: Use of quantitative MRI in a clinical populations

And I will give a talk in the session "Quantitative MRI and its confoundings" (Friday, 10/10/25) with the title "Quantitative MRI and its confounding" - I didn't choose the title🤣

Frank (Francisco J. Fritz) will present his amazing data on our ERC study. The title of his presentation "Quantitative MRI study of excised brain tissue in drug-resistant epilepsy patient: from in-vivo to ex-vivo"

And here is a little teaser

Three of our group from Lübeck will be in Marseille. Laurin Mordhorst will present his final PhD work with the title "Reaching the Tail: Validating MRI Axon
Radius Mapping with MRI-Scale Histology"

I am looking forward to the meeting!

Judith Schirmer used sodium MRI at 7T to characterize cysts in kidneys using in vivo and ex vivo measurements.

Jan-Malte Oeschger from our group in Lübeck presented our travel-head study on optimising an 1-hour clinical quantitative MRI protocol.

Marc Jonuscheit from Düsseldorf presented his work on 31P-MRS in the liver in tyoe-1 diabetes and controls. They combined T1 and P_i concentration measurements on a clinical MR system.

Federicia Calafiore from Lund presented her amazing results about measuring CSF flow in Normal Pressure Hydrocephalus.

Better late than never!

Here is a little summary of my notes during one of the sessions of the Nordic (@ismrmnordic.bsky.social) and DACH-ISMRM from two weeks ago in Kiel.