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Sarah Rice

@grainofscience.bsky.social

πŸ‡ͺπŸ‡Ί Genetics and Epigenetics Osteoarthritis Researcher 🎩 Versus Arthritis Career Development Fellow. Newcastle University research.ncl.ac.uk/ricelab

367 Followers  |  726 Following  |  86 Posts  |  Joined: 23.09.2023  |  1.722

Latest posts by grainofscience.bsky.social on Bluesky

I am shocked by the belief that it is ok to be rude in manuscript reviews. Constructive criticism & challenging drawn conclusions is integral to peer review, but journal editors need to speak out and tell reviewers when their comments are unacceptable. We're better than this.

04.08.2025 12:03 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Convergent evolution of distinct D-ribulose utilisation pathways in attaching and effacing pathogens - Nature Communications Cottam et al. identify distinct pathways for D-ribulose utilisation in pathogenic Escherichia coli and Citrobacter rodentium, providing mechanistic details and suggesting convergent evolution towards ...

Absolutely delighted to share the labs latest work. We identify and characterise two pathways for D-ribulose utilisation in pathogenic EHEC and Citrobacter.

30.07.2025 09:24 β€” πŸ‘ 30    πŸ” 13    πŸ’¬ 1    πŸ“Œ 1
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In his memory, Western has opened an equity-based graduate scholarship. Please consider supporting his final initiative if you are able: www.westernconnect.ca/beier ; thank you for all the time you spent and laughs you shared with him. We love and miss him so much already. - The Beiers

24.07.2025 15:09 β€” πŸ‘ 64    πŸ” 20    πŸ’¬ 2    πŸ“Œ 0
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Hi all. Frank passed peacefully with the love of his family on July 18, 2025 in London, ON. He was a wonderful human being who shared much of his life with you. We could not have asked for a better father, grandfather, friend, colleague, or mentor. 1/

24.07.2025 15:06 β€” πŸ‘ 99    πŸ” 14    πŸ’¬ 19    πŸ“Œ 5

I have no idea which of our collaborators are on here (Bluesky still feeling more like Blackhole) but I’m so excited to work with you all πŸ₯³ @fornerislab.bsky.social @fzaucke.bsky.social

15.07.2025 17:19 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Just when you thought all had gone quiet on the COLGALT2 front- get ready to hear more! Delighted that @hammofish.bsky.social and I have been awarded a four year grant from MRC @ukri.org to study the role of this enzyme in the skeleton. Will be advertising PDRA and RA posts in due course! #orthosky

15.07.2025 16:59 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 2    πŸ“Œ 0
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Spinger Nature Discovers MDPI – The Strain on Scientific Publishing Home page for the paper β€˜The Strain on Scientific Publishing’ by Mark A Hanson, Dan Brockington, Paolo Crosetto and Pablo Gomez Barreiro

New from The Strain Team:
🎊 Springer Nature Discovers MDPI 🎊

Springer Nature has spawned a copycat journal series called "Discover" mimicking #MDPI journal titles and citation behaviours. We even made a browser game to prove it (see πŸ”—).

Gross! πŸ˜€ 1/n

#ResearchIntegrity #SciPub #AcademicSky

10.06.2025 05:47 β€” πŸ‘ 237    πŸ” 181    πŸ’¬ 11    πŸ“Œ 32

Congrats Terry. They'e lucky to have you- especially in the current climate!

03.06.2025 13:09 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Today, I take the reigns as Chair, Human Evolutionary Biology, Harvard. Big thankyou to Dan Lieberman outgoing Chair & Joe Henrich, previous Chair. They did tremendous jobs advancing HEB's intellectual/academic vibrancy. I'll work hard for all students, postdocs & faculty in this changing landscape

29.05.2025 13:23 β€” πŸ‘ 20    πŸ” 1    πŸ’¬ 3    πŸ“Œ 0
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Harvard Sues Trump Administration Over Move to Bar International Students

We are responding legally to our President’s illegal acts! All should do the same

www.nytimes.com/2025/05/23/u...

23.05.2025 12:50 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Complex regulatory interactions at GDF5 shape joint morphology and osteoarthritis disease risk Objectives To reveal causal level osteoarthritis (OA) disease biology by targeting regulatory interactions at GDF5. Methods By investigating different GDF5 regulatory regions (R2, R3-5, R7-R9, R18...

1) Despite the chaos, I am very pleased to present the terrific research conducted by my post-doc @clarissacoveney.bsky.social. acrjournals.onlinelibrary.wiley.com/doi/10.1002/...

21.05.2025 14:11 β€” πŸ‘ 15    πŸ” 6    πŸ’¬ 1    πŸ“Œ 2

Does anyone have a Col156 plasmid (small, high-copy, not co-integrated on an F) handy they’d be willing to share? πŸ§ͺ

20.05.2025 20:17 β€” πŸ‘ 4    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0
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a woman wearing glasses is drinking from a mason jar and saying `` girls , bottoms up ! '' ALT: a woman wearing glasses is drinking from a mason jar and saying `` girls , bottoms up ! ''

It doesn't matter how many times I try to grasp this, I'll never know what you mean when you talk about "top down" or "bottom up" approaches. So please find another way to convey to me whatever point you need to make. This is a hill I'll die on.

08.05.2025 13:16 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Four images to illustrate some prominent single-gene myths. Top left shows a photograph of a person deftly rolling their tongue into a U-shape. Top right shows a photograph of a person’s ear, highlighting the shape and features of the earlobe and cartilage. Bottom left shows a close-up photograph of a person’s eye, with a vivid blue colouration. Bottom right shows a photograph of a person poised to write with their left hand on the blank white page of a spiral-bound notebook.

Four images to illustrate some prominent single-gene myths. Top left shows a photograph of a person deftly rolling their tongue into a U-shape. Top right shows a photograph of a person’s ear, highlighting the shape and features of the earlobe and cartilage. Bottom left shows a close-up photograph of a person’s eye, with a vivid blue colouration. Bottom right shows a photograph of a person poised to write with their left hand on the blank white page of a spiral-bound notebook.

Remember when you first learned about genetics at school? All those fascinating examples of human traits that are each apparently determined by just a single gene? Time to check in on some of your favourites to see how they’re doing. 🧬🧡πŸ§ͺ 1/n

02.05.2025 14:50 β€” πŸ‘ 1266    πŸ” 595    πŸ’¬ 57    πŸ“Œ 83

A huge thanks to @jackbroberts.bsky.social @cgm-newcastle.bsky.social @newcastleuni.bsky.social who led on writing/developing this report, along with co-authors Jason Rockel (Toronto) and Rick Mulders (Leiden). If you like what you read, join us in 2027 for the 4th workshop- to be held in the UK!

03.05.2025 08:35 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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From mechanism to medicine: the progress and potential of epigenetics in osteoarthritis Osteoarthritis (OA) is a chronic, degenerative disease of the articular joints. The disease presents an enormous clinical and economic burden globally…

For the 3rd #EpigeneticsOA workshop, 77 attendees united to discuss progress and potential of our field. Delighted to see the meeting report in print! Whether you made it, or missed out, catch up w/ the outcomes here --> bit.ly/42YeWnT #orthosky @oacjournal.bsky.social @versusarthritis.bsky.social

03.05.2025 08:35 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

Twice (so far) I’ve had older male professors make misogynistic comments directly stating that things I have recently achieved (the award being one of them) are due to the success or influence of other men and not my own merit 2/

25.04.2025 22:54 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 1
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Congrats to our very own Kevin Burt for scoring among the highest-rated abstracts by early career investigators at #OARSI2025.

24.04.2025 08:26 β€” πŸ‘ 11    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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So nice to be back home in Korea and excited to be at #OARSI2025! Stop by poster #595 where I’m presenting on chromatin accessibility QTLs in resting/FNF-stimulated primary human chondrocytes. I’ve been integrating eQTL, sQTL, and Hi-C data to better understand gene regulation in osteoarthritis.

25.04.2025 14:37 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

Such a great study- really enjoyed chatting to you earlier!

25.04.2025 17:35 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Hanging with my symbiont @curlygeneticist.bsky.social #OARSI2025

25.04.2025 15:07 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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I'm honoured to be in Korea this week to collect my Rising Star Award at #OARSI2025 Thank you so much to
OARSI for this award, and @beierlab.bsky.social for generously nominating me. Having a wonderful time all round πŸ‡°πŸ‡·

25.04.2025 06:21 β€” πŸ‘ 16    πŸ” 1    πŸ’¬ 4    πŸ“Œ 0

Ah, I was wondering why I hadn't spotted you yet. Really sorry to hear that. Hope to see you somewhere else soon. Look after yourself x

25.04.2025 06:10 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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After a few days exploring Seoul, I’m exited to be in sunny Incheon for #OARSI2025

24.04.2025 07:18 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you!! πŸ€—

21.04.2025 21:13 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Excited to be in South Korea for #OARSI2025 I’ve landed a few days early and I’m making the most of it!

21.04.2025 14:06 β€” πŸ‘ 10    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1

Congratulations to @fornerislab.bsky.social on the publication of their work to characterise COLGALT1 this week in @natcomms.nature.com. This is a really beautiful study and it is great to see it in print! πŸ‘πŸΌ

18.04.2025 08:40 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Well done to my PhD Student Abby Brumwell on delivering a great talk to a full room at the @mosmedcdt.bsky.social annual conference this afternoon! #ProudPI @cgm-newcastle.bsky.social

15.04.2025 15:53 β€” πŸ‘ 11    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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New preprint on 3D heterochromatin architecture in human cells! Great collab with @sergiocruzleon.bsky.social & @johannesbetz.bsky.social from @hummerlab.bsky.social, @marinalusic.bsky.social & the TuroňovΓ‘ lab. Many thanks to my supervisor @becklab.bsky.social. bioRxiv: tinyurl.com/3a74uanv πŸ§΅πŸ‘‡

11.04.2025 09:03 β€” πŸ‘ 224    πŸ” 67    πŸ’¬ 3    πŸ“Œ 4
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A timely assessment of the state of transcriptomic and epigenomic profiling in OA: Opportunities for advancements

Our Editorial is now online! Here, we discuss recent advancements and pertinent challenges in applying modern 'omics technologies to MSK tissues. This introduces our @oacjournal.bsky.social special edition. Still ~4 weeks left if you have a paper in the works! www.sciencedirect.com/science/arti...

05.04.2025 11:50 β€” πŸ‘ 9    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

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