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Nancy Santiappillai

@nancyts.bsky.social

Postdoc fellow in the Keshari lab @MSKCC interested in cancer metabolism, mass spec, imaging, and therapeutics. πŸ‡³πŸ‡Ώ -> πŸ‡¦πŸ‡Ί-> πŸ‡ΊπŸ‡ΈπŸ—½

62 Followers  |  111 Following  |  1 Posts  |  Joined: 20.11.2024  |  1.3854

Latest posts by nancyts.bsky.social on Bluesky

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reactant and product metabolite ratios revealed metabolic pathways differences between cancer subtypes and noncancer cell lines by @hoylipidlab.bsky.social @sydneyprecisionds.bsky.social @nancyts.bsky.social ➑️ www.embopress.org/doi/full/10....

03.07.2025 10:11 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells | Molecular Systems Biology imageimagePathway-focused metabolite ratio-based analysis of 49 tumor and 8 normal epithelial cell lines grown in their respective standard conditions reveals common and distinctive metabolic signatur...

Incredibly proud of our latest publication in @molsystbiol.org led by @nancyts.bsky.social in collab w/ Jean Yang and Lake-Ee Quek - www.embopress.org/doi/full/10....
We curated targeted metabolomic data into pathway-centric ratios and identified subclusters of cancer cells with distinct features.

06.06.2025 01:23 β€” πŸ‘ 22    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0
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Had a great time sharing our work on macrophage TNBC symbiosis at the NYAS Cancer and Metabolism symposium!

08.04.2025 21:39 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Sweet success in CAR T cells - Nature Reviews Cancer Glycolysis-dependent T cell function is hindered by glucose scarcity in the tumour microenvironment. Now in Cancer Cell, Schild et al. engineered T cells to utilize fructose via GLUT5, enhancing their metabolic activity and cytotoxicity.

In @cp-cancercell.bsky.social, Schild et al. @mskcancercenter.bsky.social engineered T cells & CAR T cells to express the fructose-specific transporter GLUT5, improving T cell glycolytic flux & thus effector function in glucose-limited conditions.
πŸ“– the #researchhighlight πŸ‘‡

01.04.2025 14:53 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

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