Siegenthaler Lab

And yet more reporting showing the gravity of the problem when federal agencies terminate grants or return applications without review for reasons unknown. The absence of public accountability continues to have cascading impacts on science and scientists.

www.science.org/content/arti...

Excited to share this new Preprint from our lab led by PhD Candidate Carl Stone (defending Tuesday).

Here we present a framework for longitudinal rbTn-Seq and apply it to the Microbial extended growth curve to resolve the fitness seascape through growth, death, and long-term stationary phase!

Exciting day of science yesterday @uni-of-warwick.bsky.social

Our Cellular Interfaces Cluster (CIC) had its first symposium!

The CIC brings together researchers with a wide range of expertise establishing a collective effort to understand cellular interfaces directed by Jitu Mayor.

There is No Scientific Justification to Revoke the Endangerment Finding The U.S. EPA's decision to repeal the Endangerment Finding will limit the government's ability to regulate emissions of carbon dioxide and other greenhouse gases under the Clean Air Act.

As I say here, there is no scientific justification to revoke the engagement finding. In fact, over the last 15+ yrs, the evidence of how climate change affects our health has only grown. Higher risk of allergies, dementia, fertility, heart disease, and death: that’s what’s on the line. @nature.org

Speak to @ingridtsang.bsky.social if you'd like a copy of @dev-journal.bsky.social's 'Stem cell-based models of early human development' poster by @liliulab.bsky.social and @jun-wu-lab.bsky.social

You can read the article here: doi.org/10.1242/dev....

My genes crafted a brain aneurysm and the expertise of researchers and doctors saved me Because of new surgery techniques—that weren't available to my relatives who suffered the same affliction as I do—I'm here and able to exercise my love of language.

Defunding scientific research and maligning doctors’ expertise matters: a perspective from my emergency room visit.

@themedicalpost.bsky.social (gated - PDF from my website below)

canadianhealthcarenetwork.ca/my-genes-cra...

PDF: static1.squarespace.com/static/5f789...

#AcademicSky
#MedSky

“Though Black women only account for about 14% of the workforce, they represented over half of all women’s job losses during the U.S. employment market’s most volatile months in 2025, like March, April, June, and December.”

nobody posted the clip anywhere so i went and dug the whole episode up

Trump nominates hospitality executive to lead National Park Service Scott Socha, whose company sued to claim trademark rights to Yosemite name, criticized by conservation groups

"Donald Trump has nominated the hospitality executive Scott Socha – whose company once sued to claim trademark rights to the name 'Yosemite National Park' – to lead the National Park Service." #FFS #NationalParks www.theguardian.com/us-news/2026...

I am seeking a postdoc to join my group at UCLA -- ideally the candidate would have some experience in either population genetics or microbes/microbiome (computational background needed). We have a range of projects and are happy to tailer to your interests. Please dm/email me if interested.

Focus on stem cell models in embryology Development has a long history of publishing papers in embryology, spanning over 70 years. Today, the field is incredibly exciting, with the generation of stem cell-based models providing new systems with which to study particularly elusive stages of early development, including pre-implantation, implantation and gastrulation. Curated to coincide with the 2026 ‘Stem Cell Models in Embryology’ meeting from Keystone Symposia in California, USA, this collection from Development's Editor-in-Chief James Briscoe showcases recent papers on stem cell models of embryonic development. James will be attending the meeting along with Development Reviews Editor, Ingrid Tsang. We hope this collection piques your interest, and we welcome your own submissions on stem cell-based models, and early embryonic development, for consideration by our expert Editors, including James Briscoe, Anna-Katerina Hadjantonakis, Matthias Lütolf, Liz Robertson, Peter Rugg-Gunn, Debby Silver and Jim Wells. Please also consider registering your interest ‘Human Development: Stem Cells, Models, Embryos’ meeting from Development and the Human Developmental Biology Initiative (HDBI) in September 2026.

Interested in the 'Stem Cell Models in Embryology' conference from @keystonesymposia.bsky.social?

Browse our 'Focus on stem cell models in embryology' subject collection, curated by Editor-in-Chief, @jamesbriscoe.bsky.social especially for the meeting.

journals.biologists.com/dev/collecti...

Our take on a really interesting new study by the Franz lab at UCL, a version of epithelial polarity where you would not expect it! Read our Spotlight and the original paper!

Ogden lab at happy hour - Harsh Kumar, Rojalin Pradhan, Sam Hack, Christina Daly, Stacey Ogden, Daniel Stewart, Christina Wang, Hong Lin

Celebrating 1) a review article being provisionally accepted 2) @christinaadaly.bsky.social getting her first author research paper submitted, and 3) The International Day of Women and Girls in Science! 🎉 Woo hoo! 🧪

High resolution spatial transcriptomic and proteomic profiling of early primate gastrulation in utero https://www.biorxiv.org/content/10.64898/2026.02.10.705168v1

Two axolotl-adapted cell-ablation platforms reveal macrophage-dependent processes essential for spinal-cord and skeletal regeneration https://www.biorxiv.org/content/10.64898/2026.02.10.705144v1

Can listening to certain sounds really treat Alzheimer's Disease? Alzheimer’s disease is related to the build-up of amyloid plaques and tau tangles in the brain, but it is also characterised by disrupted patterns of brain signalling. The brain works through…

Can listening to certain sounds really treat Alzheimer's Disease? www.kcl.ac.uk/can-listenin... by @kingscollegelondon.bsky.social

#Alzheimers #dementia #science #neuroscience #NeuroSkyence

The NAACP was founded on this day in 1909. Today, we celebrate their work in advancing Black Americans' rights in the fight towards a more equal and just nation for every American.

Thank you for over a century of your unwavering commitment!

Photo of NAACP leaders meeting at a 1916 conference.

Happy birthday, NAACP! Thank you for 117 years of fighting to ensure that every American can live in freedom under the protection of our sacred constitutional rights.

Your work is more important than ever as we fight civil rights abuses to protect the progress we’ve made. #BHM2026

Someone told me lately "Bluesky is just like Twitter." I argued that was untrue on the basis that last time I had a Twitter account most times I got a new follower their bio said "single & looking for fun" & here when I get a new follower it tends to say something like "professor of rare moths".

CU Anschutz Medical Student Tessa Petersell Set to Compete in Collegiate Powerlifting Nationals CU Anschutz School of Medicine student Tessa Petersell found powerlifting after retiring from gymnastics. Her dedication led her to a national competition.

CU Anschutz School of Medicine student Tessa Petersell is heading to Louisiana this April to compete at the USA Powerlifting Collegiate Nationals! 🏋️‍♀️ Read her story: https://bit.ly/3OyaqIZ

I cannot stress enough how much these kinds of notes mean to teachers.

Or anyone, really. If someone has made a positive impact on your life, reach out and let them know. It'll make their week.

I would ask people to call or message their senators about this and specifically that Vinay Prasad needs to be out at FDA. Even the Wall Street Journal has said as much. There is push back. Companies won’t fund clinical trials if they can’t trust the FDA.

Indigenous woman Dr. Krystal Tsosie in front of an event poster

Forgot my ID at check-in — thankfully this event sign vouched for me 🙂

If you’re at the @aaas.org meeting tomorrow (Fri 2/13, 4–5 PM) at Phoenix Convention Center, see why “The Future of #Science is #Indigenous”

Genomics, #AI, #health — what we build matters. How we build it matters more. #AAASmtg

Today I had to vouch for another parent to a substitute bus driver so they'd let the woman's son get off the bus and go home with her. The woman didn't have her ID on her and the sub was REALLY shitty about it. But we've never NEEDED ID to get our kids.

A mini storytime. (1/?)

Interested in transcriptional regulation, enhancers and 3D genome folding?

In this new study we wondered about the role of cohesin loading at enhancers for long-range transcriptional control

www.biorxiv.org/content/10.6...

detailed 🧵👇

EBV reprograms autoreactive B cells as antigen presenting cells in multiple sclerosis https://www.biorxiv.org/content/10.64898/2026.02.11.701910v1

I am sure Vinay Prasad must be very happy now.
Drunk on power and outrage, thwarting scientific progress on his merry way. What an awful legacy for a physician to choose.

We have posted a Research Assistant (LSRP1) position to work on aging and 'rejuvenation' using mouse models!! 🐭

careersearch.stanford.edu/jobs/life-sc...

Apply and join our awesome lab!! (please share) 😎

YouTube video by PBS NewsHour Opera singer Denyce Graves takes her final bow on stage

Acclaimed mezzo soprano Denyce Graves took a final bow last month and is pivoting to teaching the next generation. She performed on the world’s top opera stages for more than 40 years.

Such a brilliant, beautiful person. And now she's speaking about the racism she faced.

#Opera #Classical #BHM

Summary of training updates discussed at NIGMS council. www.faseb.org/journals-and...