Siegenthaler Lab

Day two of #CBIAS2025 kicked off by @lankylaste.bsky.social from @crick.ac.uk and the first session is on physical and mathematical modelling chaired by @natalieah.bsky.social , with the first presenter Ewa Paluch from @cam.bsky.social

Second speaker is @teunhuijben.bsky.social from @loicaroyer.bsky.social group at @czbiohub.bsky.social #CBIAS2025
Tracking is hard because segmentation is hard, especially in whole zebra fish embryos: Ultrack can help github.com/royerlab/ult...

Therapeutic VEGFC treatment protects against traumatic brain injury-driven tauopathy pathogenesis @cp-cellreports.bsky.social
www.sciencedirect.com/science/arti...

Resolving the mysteries of brain clearance and immune surveillance: @cp-neuron.bsky.social www.cell.com/neuron/fullt...

National Academies - Statement on CDC’s Updated Vaccine Guidance National Academies respond to CDC’s updated vaccine guidance, offering scientific context and clarity on vaccine safety.

Statement from @health.nationalacademies.org "...based on our body of work on this topic and the overwhelming scientific consensus, we support the statement that vaccines do not cause autism."
www.nationalacademies.org/news/stateme...

Rad power bikes battery

CPSC Warns Consumers to Immediately Stop Using Batteries for E-Bikes from Rad Power Bikes Due to Fire Hazard; Risk of Serious Injury or Death www.cpsc.gov/Warnings/202...

Tye Leung Schulze became the first Chinese American woman to vote in a U.S. election in 1912. She worked as a translator at Angel Island and fought for immigrant women and girls. Her courage opened doors in a country that tried to keep them shut. #WomenInHistory #WomenInSTEM
shorturl.at/psm1I

NYC Mayor-elect Zohran Mamdani announces transition committees New York City Mayor-elect Zohran Mamdani​ announced Monday the creation of 17 transition advisory committees made up of more than 400 people.

Honored to serve on Mayor-elect @zohrankmamdani.bsky.social Transition Committee on Technology. For too long, too many New Yorkers have been left behind. NYC deserves governance that centers affordability, equity, and the public good-looking forward to the work ahead. www.cbsnews.com/newyork/news...

Application review launches on December 1, 2025. We want to read *your* application outlining a vision for a research program deciphering how membrane proteins collaborate to enable cell function, their biosynthesis, and the biophysics and structure of how membrane proteins change shape.

1/ Thanksgiving week is here! Between viral updates, family debates, and public health headlines, there’s a lot to cover. So let's do a quick breakdown of what’s on our radar this week so you can get back to prepping the turkey👇

8/ Some good news from science this week:
✔️ 86 million girls in high-risk countries are vaccinated against HPV. This has prevented 1.4 million deaths prevented
✔️ Clinical trial data shows the mRNA flu vaccine to be 34.5% more effective than a licensed seasonal flu vaccine

7/ The broader consequences are significant: fewer trained professionals, more barriers for students from low-income backgrounds, and added strain on already stretched health and social systems. A formal proposal will be released in the next few weeks, which launches a 30-day public comment period.

6/ The Department of Education has removed MPH & DrPH programs from their draft definition of what counts as a“professional degree.” If this sticks, it could limit federal aid, scholarships, and loan repayment for students, making it harder to enter public health careers.

Huge congratulations to Hoang Nguyen from CellSight! 🎉
His image was selected for the cover of Ophthalmology Science — an incredible recognition of his creativity and contribution to vision science.

We’re so proud to celebrate this achievement! 👏

Another proud bench mentor alert! 🌟 Congratulations to Nimo Abdi for receiving a presentation award in Biochemistry and Molecular Biology at the 2025 #ABRCMS conference!!! PS: she is also applying for summer research internships, and I highly recommend her! 🧪🔬👩🏿‍🔬 @rutterlab.bsky.social @hhmi.org

Time to start planning for ASM Microbe 2026! Among the amazing sessions announced (see link), Chris and I are thrilled to be convening “From the Rhizosphere to Pollinators: Studying Agricultural Microbiomes Across Biological Scales”. We can’t wait to see you all there! More details coming soon!

Hawkeye WR Seth Anderson showed up BIG - donating 30 turkeys to the Iowa City Catholic Worker! Defensive backs Kael Kolarik and Koen Entringer jumped in to help distribute them to volunteers who’ll roast & share them with immigrant families across our community. That’s what teamwork looks like ! 🏈🙌

Attn all human MRI/fMRI folks! The Dept of Psychology at Northeastern University is hiring a new Director of the NU Biomedical Imaging Center at the level of Associate or Full Professor. Bonus: you'll have the best Chair EVER 😉 Full ad here: northeastern.wd1.myworkdayjobs.com/careers/job/...

The data center boom in the desert The AI race is transforming northwestern Nevada into one of the world's largest data-center markets—and sparking fears of water strains in the nation’s driest state.

Data centers popping up on Indigenous lands everywhere, but especially perilous to us desert tribes where water availability for crops and for communities have new competition.

Here we go. Its ALL #NIHGrant applications. Dec 8 is the new deadline. And a one page prelim data update will be accepted for all May Council submissions. grants.nih.gov/grants/guide...

Nice overview on the knowns and unknowns about pathways and mechanisms governing brain immunity and clearance. 🫶🏻😃

“Resolving the mysteries of brain clearance and immune surveillance”

Check it out 👇🏻
authors.elsevier.com/sd/article/S...

Judge Dismisses James Comey, Letitia James Indictments A federal judge has dismissed criminal cases against former FBI Director James Comey and New York Attorney General Letitia James.

A federal judge has dismissed the criminal cases against former FBI Director James Comey and New York Attorney General Letitia James, concluding that the prosecutor who brought the charges at President Donald Trump’s urging was illegally appointed by the Justice Department.

buff.ly/0bESYEn

Check all the NIH review deets for deadlines during the shutdown here! 🧪

“Summary statements will be simplified. Narrative paragraphs summarizing committee discussion will not be used. Instead, summaries will have a sentence describing the degree of consensus in the committee vote, plus bullets listing the main score driving points.” FYI

Some very profound changes. NDs will be split into competitive vs non-competitive, and competitive NDs could conceivably still get funded.

And summary statements will be very abbreviated with a sentence on level of SS consensus, and then bullet points on score driving strengths and weaknesses.

Updated guidance on NIH grant application due dates (10/1/2025-12/5/2025), along with some other Info. grants.nih.gov/grants/guide...

Applications are now open for the 2026 Developing Future Biologists Short Course at the University of Michigan!

Visit our website or email contactdfb@umich.edu to learn more and apply. #GoBlue

Tell your undergrads about this. It’s a fantastic short-course in Ann Arbor, all expenses covered. Do some experiments in developmental biology and learn about careers in research and life as a grad student 🧪

Unfortunately, I can confirm that this is true.

I have known Carl for 2 decades and he is smart, dedicated, and quite apolitical, focused on science and getting stuff done on important problems.

Huge unnecessary loss of leadership and expertise.

'Nobody wants to come': What if the U.S. can no longer attract immigrant physicians? Immigrants make up a significant proportion of all the country's doctors. New policies are making it harder and less appealing for foreign-born physicians to come to the U.S.

In the least surprising news ever:
"It feels like my contribution is — just because I was not born in this country — less valued," Liu says…defunding scientific research and public health have damaged the U.S.'s reputation…top international talent are no longer interested in coming to America.”