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Filippo Binci

@filbinci.bsky.social

Post-Doc at UniPD. Working on calcium signalling in plant development and plant-microbe interactions #PlantScience #MPMI

125 Followers  |  496 Following  |  16 Posts  |  Joined: 06.11.2024  |  2.3142

Latest posts by filbinci.bsky.social on Bluesky

Plan U, for universal, is the necessary standard. Post everything as a preprint at or before point of submission. Then publish in any journal you want but never pay exorbitant APCs.

24.09.2025 20:04 β€” πŸ‘ 6    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

Dear @dfg.de & @erc.europa.eu Why don't you do the same? What's stopping us from adopting this model to all tax-payer funded research in Europe? journals.plos.org/plosbiology/...

25.09.2025 05:40 β€” πŸ‘ 21    πŸ” 11    πŸ’¬ 1    πŸ“Œ 0

6/6) Overall, LjMLO4 is a key molecular hub between peptide signalling, Ca2+ transport and root system architecture, highlighting MLO integration of developmental, nutrition and symbiotic cues.

Thanks to my supervisors, collaborators and MSc students!

Feel free to get in touch for comments!

22.09.2025 08:05 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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5/6) Then, we tested mlo4 responsiveness to exogenous treatments with Lj RALF peptides. We found that mutants are less sensitive to LjRALF34 than WT in terms of root growth inhibition and Ca2+ signalling, supporting recent evidence of MLO as signal amplifiers of the RALF/CrRLK1L signalling

22.09.2025 08:05 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

4/6) Given the recently proposed role of MLO functioning as Ca2+ channel downstream of RALFs, first we tested that LjMLO4 can mobilize Ca2+ across biological membranes by heterologous expression in E. coli.

22.09.2025 08:05 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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3/6) Surprisingly, no major AM-related phenotypes were visible in mlo4 mutants, but we uncovered clear root developmental phenotypes irrespective of root colonization by AM fungi. mlo4 mutants have shorter and fewer lateral roots, and this is dependent on exogenous Ca2+ levels.

22.09.2025 08:05 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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2/6) We found that the promoter of LjMLO4 has a dual expression pattern in roots: strongly activated in arbusculated cells and a basal expression at lateral root primordia and root tips

22.09.2025 08:05 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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A symbiotic MLO gene regulates root development via RALF34-triggered Ca2+ signalling in Lotus japonicus Mildew Locus O (MLO) genes, initially identified as powdery mildew susceptibility factors, are increasingly recognized as multifunctional regulators implicated in diverse processes including plant rep...

1/6) Third effort from my PhD with @magiovan.bsky.social and @lorellanavazio.bsky.social, happy to see it online!

We show that a symbiotic clade IV MLO (LjMLO4) regulates root development and responses to endogenous RALF34 via calcium signalling in Lotus japonicus

www.biorxiv.org.

22.09.2025 08:05 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 1    πŸ“Œ 1

In the MSCA global fellowship there is a mandatory "outgoing phase", for mobility from the chosen european host to an "outgoing country" out of Europe and back.. EU bureaucratic language can be misleading :)

14.09.2025 16:59 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

I think both graphs gather applications for the chosen destination (in Europe or abroad). No data here about the country of origin of applicants, but only where they would like to go

14.09.2025 16:14 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
MSCA Postdoctoral Fellowships 2025 receives record number of 17,058 proposals This year’s annual MSCA Postdoctoral Fellowships call has attracted considerable interest from the research community with 17,058 proposals submitted.

record 17,058 Marie Curie proposals in 2025 vs. 10,360 in 2024!!! the reason is pretty obvious, but wow that is a huge jump marie-sklodowska-curie-actions.ec.europa.eu/news/msca-po...

13.09.2025 18:04 β€” πŸ‘ 39    πŸ” 23    πŸ’¬ 2    πŸ“Œ 11
The image shows one straight magenta line and, close to it, another wavy green line.

The image shows one straight magenta line and, close to it, another wavy green line.

This might be one of the simplest images I captured, but very fascinating nonetheless, as it shows how tight the cytoplasm in a plant cell is. The cytosol and all other organelles are squished between the plasma membrane (magenta) and the central vacuole (its membrane is green)
#MicroscopyMonday

08.09.2025 16:22 β€” πŸ‘ 117    πŸ” 30    πŸ’¬ 7    πŸ“Œ 2
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Head of Service Unit Proteomics

Attention plant proteomics specialists: We are looking for a Head of our new Proteomics Unit at our international and dynamic Max Planck Institute of Molecular Plant Physiology. @mpi-mp-potsdam.bsky.social Applications are welcome until 30. Sept 2025: jobs.mpimp-golm.mpg.de/jobposting/8...

23.08.2025 08:27 β€” πŸ‘ 36    πŸ” 54    πŸ’¬ 0    πŸ“Œ 0

"If you’re a scientist, you’re in the business of producing and communicating knowledge.

It’s worth reminding ourselves: the goal isn’t simply to publish papers. The goal is to produce knowledge that yields predictable outcomes β€” science that stands the test of time"

04.08.2025 13:01 β€” πŸ‘ 7    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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A plant Lysin Motif Receptor-Like Kinase plays an ancestral function in mycorrhiza | PNAS Arbuscular mycorrhiza (AM) with soilborne Glomeromycota fungi was pivotal in the conquest of land by plants almost half a billion years ago. In flo...

I’m very happy that my main PhD work, under the supervision of @malick-mbengue.bsky.social, found a home in @pnas.org
Two days before my PhD defence! πŸŽ‰ (1/6)

12.06.2025 08:27 β€” πŸ‘ 46    πŸ” 27    πŸ’¬ 2    πŸ“Œ 4
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The latest publication from our lab!

The famous "glomalin" from arbuscular mycorrhizal (AM) fungi is not a protein but a polysaccharide from AM fungi, so we renamed it "glomalose". Glomalin-related proteins are bacterial proteins stuck in this glomalose.
nph.onlinelibrary.wiley.com/doi/10.1111/...

06.06.2025 13:54 β€” πŸ‘ 73    πŸ” 40    πŸ’¬ 3    πŸ“Œ 0
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Functional divergence of plant SCAR/WAVE proteins is determined by intrinsically disordered regions Intrinsically disordered regions in SCAR/WAVE proteins drive diverse functions in root hair and leaf trichome development.

Excited to share that our preprint has found a home in Science Advances. We show that intrinsically disordered regions determine the functional diversification of actin-regulatory SCAR proteins in Medicago. 🧡 1/3
www.science.org/doi/full/10....
#ScienceAdvances #PlantScience #IDRs

21.05.2025 19:27 β€” πŸ‘ 42    πŸ” 17    πŸ’¬ 2    πŸ“Œ 1
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The burning glass effect of water droplets triggers a high light-induced calcium response in the chloroplast stroma Plants rely on water and light for photosynthesis, but water droplets on leaves can focus light into high-intensity spots, risking photodamage. Excess…

What started as a 'funky' observation back in 2017 while visiting the lab of @labcosta.bsky.social, and after skilfull execution of Dominic Kuang, Shanna Romand, and many more, now found a home in Current Biology. www.sciencedirect.com/science/arti...

20.05.2025 15:21 β€” πŸ‘ 14    πŸ” 8    πŸ’¬ 2    πŸ“Œ 0

Proud to have contributed to this during my MSc thesis @carogutj.bsky.social lab. Thanks to Michi Paries and congrats to all involved!

20.05.2025 11:13 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Contratti per i ricercatori: sciopero contro tagli, precarietà e guerra Torino, Milano, Siena, Bologna, Roma, Palermo, Napoli, Venezia e molte altre città il 12 maggio scorso hanno visto scendere in piazza i precari delle università. È stato il primo sciopero nazionale ad...

In molte cittΓ  italiane il 12 maggio scorso i precari delle universitΓ  sono scesi in piazza. Al centro del dibattito c’è il contratto di ricerca istituito dal governo Draghi in sostituzione degli assegni di ricerca. Contestate le modifiche proposte dal governo

www.scienzainrete.it/articolo/con...

15.05.2025 08:43 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1

Congrats Sagar!

15.04.2025 06:34 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Absolutely thrilled to share our storyβ€”please take a moment to check it out! Huge thanks to all the contributors and my amazing supervisor @lmueller.bsky.social . This was truly a team effort! #peptides #mycorrhiza

www.pnas.org/doi/10.1073/...

15.04.2025 00:15 β€” πŸ‘ 18    πŸ” 7    πŸ’¬ 3    πŸ“Œ 0

Excited to share our latest publication in bioRxiv regarding the response of lettuce to a soil microbial consortium πŸ₯¬πŸ¦ .
@magiovan.bsky.social

03.04.2025 07:08 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 1    πŸ“Œ 1

Plant genetic and root-associated microbial diversity modulate Lactuca sativa responsiveness to a soil inoculum under phosphate deficiency https://www.biorxiv.org/content/10.1101/2025.04.02.646582v1

02.04.2025 16:03 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Il lato umano della scienza: la ricerca come attivitΓ  sociale | Il Bo Live UniPD La scienza Γ¨ neutrale? I dati sono solo una rappresentazione dei fatti? A queste questioni si dedica la ricerca di Sabina Leonelli, filosofa della scienza, a cui abbiamo posto alcune domande sulla nat...

Italian readers: articolo intervista sul β€œlato umano della scienza” e la relazione tra #scienza e #filosofia, messo insieme da Sofia Belardinelli a Padova: ilbolive.unipd.it/it/news/scie... #philsci πŸ§ͺ

31.03.2025 05:56 β€” πŸ‘ 14    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
Homepage - openRxiv openRxiv is an independent non-profit, the new organizational home for bioRxiv and medRxiv, enabling researchers to instantly share groundbreaking findings with the global scientific community.

Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n

11.03.2025 13:20 β€” πŸ‘ 2573    πŸ” 851    πŸ’¬ 55    πŸ“Œ 42
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Conservation of symbiotic signaling since the most recent common ancestor of land plants | PNAS Plants have colonized lands 450 million years ago. This terrestrialization was facilitated by developmental and functional innovations. Recent evo-...

Really pleased to transition from 2024 to 2025 with Tatiana Vernie's work on the evolution of the common symbiosis pathway published @pnas.org πŸ”½

We finally demonstrate that ☘️ have maintained a genetic pathway to engage withπŸ„for half a billion years!

www.pnas.org/doi/10.1073/...

01.01.2025 12:05 β€” πŸ‘ 129    πŸ” 60    πŸ’¬ 4    πŸ“Œ 3
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I want this: Genome-edited Chardonnay grapes resistant or tolerant to mildew & powdery mildew!
Did you know that grapes are grown on only ~5% of European agricultural land, but account for ~2/3 of all fungicide sprayed in Europe?
onlinelibrary.wiley.com/doi/full/10....
#plantscience

13.12.2024 17:47 β€” πŸ‘ 137    πŸ” 52    πŸ’¬ 5    πŸ“Œ 3

Cytoplasmic calcium influx mediated by Lr14a regulates stomatal immunity against leaf rust in wheat https://www.biorxiv.org/content/10.1101/2024.12.10.627212v1

12.12.2024 10:04 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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In one year, I genetically engineered the boring Arabidopsis into a beautiful ornamental flower 🧬🌹

Here is how and why I gave this model organism a visual upgrade 🧡(1/7)

12.12.2024 11:23 β€” πŸ‘ 466    πŸ” 180    πŸ’¬ 22    πŸ“Œ 38

@filbinci is following 20 prominent accounts