Asaf Levy

This is hilarious for Nobel week.
The headstones of two late Yale chemists who shared the department at the same period.
One has his CV written on the headstones
The other: Nobel Laureate etc.

And the funny story about Onsager's son adding "* ETC" after many years:
freakonomics.com/2009/09/etc-...

Two years into this bloody war that caused so much pain and loss.

RFK Jr. should definitely get a Nobel in economics for reducing housing prices in the US

40 years ago Carol Greider and Elizabeth Blackburn reported about a new enzyme in the protozoon Tetrahymena called "telomere terminal transferase"
Known today as telomerase.
They received the 2009 Nobel in physiology and medicine.
The same organism also 'contributed' to science the 1st ribozyme.

Photosynthate distribution determines spatial patterns in the rhizosphere microbiota of the maize root system - Nature Communications The combination of isotopic tracers with root phenotyping reveals specific patterns in photosynthate allocation. These patterns are reflected in rhizodeposition and result in spatially distinct microbiomes within the plant root system.

A very cool work on plant carbon exudation into the root and rhizosphere by Claudia Knief

www.nature.com/articles/s41...

he Department of Plant Pathology at the University of California, Davis is seeking applications for a fulltime, tenure-track Assistant Professor position in Mycology, with a focus on plant pathogenic, symbiotic, or mycotoxigenic fungi and fungal-like organisms (e.g., oomycetes). We are looking for a highly motivated and creative scientist with a strong background in mycology and/or the biology of fungi and fungal-like organisms that interact with plants. The successful candidate will be expected to develop a world-class, externally funded research program that integrates both fundamental and applied aspects of fungal biology within the context of plant pathology. We welcome applicants pursuing a wide range of research topics related to plant-associated fungi, including but not limited to mechanisms of fungal pathogenesis or symbiosis with plants, population genomics and evolution of fungal plant pathogens, plant-associated fungal microbiomes and plant-microbe interactions, and/or one health approaches to fungal diseases and antifungal resistance. Applicants working in other relevant research areas involving pathogenic, symbiotic, or mycotoxigenic fungi or fungal-like organisms that affect plant health are also encouraged to apply. The successful candidate will have significant opportunities for collaboration with faculty in plant pathology, microbiology, genomics, and agricultural sciences, and to contribute to addressing issues of importance to California’s agricultural and natural ecosystems. The appointee primary teaching responsibilities will be teaching Introductory Mycology, an upperdivision lab class, and SAS 30, Mushroom, Molds & Society, a general education class for non-majors. Additional graduate and undergraduate teaching responsibilities may be assigned based on departmental needs and the candidate’s expertise. The department offers modern instructional facilities, including a newly renovated teaching laboratory.

Please repost -- The Univ. California Davis dept of Plant Pathology is hiring a Fungal biologist / Mycologist

Applications due Dec 1

Application portal: recruit.ucdavis.edu/JPF07339

Screenshot shows part of the job posting (with alt-text of the same text)

Nobel prize week is approaching.

In 1980 Paul Berg was awarded the Nobel prize on recombinat DNA development.

Does anyone know why were Herbert Boyer (Genentech co-founder) and Stanley Cohen left out of this honor?
Both of them are still alive to correct a mistake...

uniQure company reports gene therapy clinical trial results showing that miRNA-like silencing of the huntingtin gene slowed progression of the Huntington’s disease by 75% after three years.
The miRNA is delivered by AAV via a neurosurgery.

Amazing.
I don't hold their stocks...

Quite insane if true

Proteolytically activated antibacterial toxins inhibit the growth of diverse Gram-positive bacteria Many species of bacteria produce small-molecule antibiotics that enter and kill a wide range of competitor microbes. However, diffusible antibacterial proteins that share this broad-spectrum activity ...

A recent cool preprint by John Whitney's lab on a new family of antibacterial proteins secreted by Gram-positive bacteria that enter and kill a broad spectrum of bacteria. Cell entry is receptor-independent and relies on cleavage by a co-secreted protease and the PMF.
www.biorxiv.org/content/10.1...

40 years ago Eyal Bartov took a picture of one of the last beautiful leopards in Israel, resting next to the dead sea. Unfortunately they have probably gone extinct in Israel.
The last one was seen in 2007.

Classic name

Shana Tova.
Happy new Jewish year.

Wishin for a scientifically productive and a peaceful year, with normal leadership around the world.

With the depressing reality of the ongoing horrible war (including a mssile alarm during the ceremony) there is a small moment of joy:
Three students from the lab received MSc degrees today:
Ofir Segev, summa cum laude
Aleks Danov, magna cum laude
Avital Akerman, magna cum laude

#uberProudPI

Benicio del Toro (center) was not famous enough to be mentioned on the poster.

Keyser Söze was introduced 30 years ago.

The pictures are quite dark but clear.

@isbergralph.bsky.social

E. coli K-12 strain into an organism capable of invading cultured animal cells."

The protein name "invasin" was coined by them in their following Cell 1987 paper.

On this week, 40 years ago, my friend Ralph Isberg, then a postdoc with Stan Falkow, reported the discovery of the 1st invasin gene in @nature.com "We report here the identification of a single genetic locus from this organism (Y. pseudotuberculosis) that is sufficient to convert the innocuous

Thanks, Jean-Michel!

Lab's 7th birthday, farewell to summertime in Palmahim beach.

Postdoctoral candidates must be citizens of the United States or Canada or have a documented status that allows them to remain permanently in the US.

Zuckerman STEM Leadership Program | Empowering Future Scientific Leaders The Zuckerman STEM Leadership Program supports top scholars in science, technology, engineering, and math through research opportunities in the U.S. and Israel.

Are you interested in joining our lab as a molecular microbiologist postdoc fellow to study new antimicrobial proteins or new bacterial genes that facilitate adaptation to different hosts?

Check out The Zuckerman STEM Leadership Program which offer generous funding.
zuckermanstem.org

Why was there so much resistance in the beginning of 20th century @baym.lol ?

By Alex Taubin

Try the 9mer DnaA box sequence. It interrupts with chromosomal DNA replication.

A vast collection of microbial genes that are toxic to bacteria In the process of clone-based genome sequencing, initial assemblies frequently contain cloning gaps that can be resolved using cloning-independent methods, but the reason for their occurrence is large...

We developed PanDaTox many years ago of genes that are toxic to E. coli. Not sure it is still online. "A vast collection of microbial genes that are toxic to bacteria" - PMC share.google/AYEOitn13a4o...

Gamma-Mobile-Trio systems are mobile elements rich in bacterial defensive and offensive tools - Nature Microbiology GMT-containing genomic islands in Vibrio parahaemolyticus and other diverse bacteria serve as a stockpile of immune and anti-phage defence systems, antibiotic-resistance genes and offensive tools such...

We covered the highly elegant Gamma-Mobile-Trio paper in our lab's journal club.
Highly recommended reading,
by my colleagure @drdorsalomon.bsky.social

www.nature.com/articles/s41...