Florey Lab

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Don't know about him joining ICE.....

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It is disappointing. Some real results are sunk by lazy and deceitful decisions on others. How many research hours/$$££ are wasted following some of those observations?

Another excellent study showing #CASM at play in plant stress responses!

My guess... the LC3B structures are not all autophagosomes #CASM

Neighbors may not like our overgrown lawn. But if it lets wild flowers like this grow, who cares! Bee Orchid #biodiversity

Thanks, and the same to you too.

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7 months later....BBSRC grant scored 6,6,5,4 (out of 6) - rated excellent. Committee D: Not funded.

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How I arrived on Bluesky

Say Hi to Mike Overholtzer if you see him!

Sometimes science can wait

Unbelievable. Richard Youle, winner of the Breakthrough Prize for Life Sciences, just got fired from the NIH. If you want to know what madness looks like, here it is, my friend.

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It was wonderful to be part of this story. Well done everyone. We enjoyed hosting you and look forward to your return this summer!!

🚀Our latest work reveals how RAB5c orchestrates LC3-associated phagocytosis (LAP) to boost macrophage defense against A. fumigatus! 🦠🔬
🧵 Dive into the mechanisms linking endosomal traffic to innate immunity!
#Immunology #Autophagy #Phagocytosis #Macrophage #Preprint
doi.org/10.1101/2025...

Congrats to Ian Ganley of Dundee University on winning the #BSCB Hooke Medal 🥇for his outstanding work on mitophagy 🎉🎉🌟

Mycobacterium tuberculosis phagosome Ca2+ leakage triggers multimembrane ATG8/LC3 lipidation to restrict damage in human macrophages Ca2+ leakage triggers LC3 lipidation on multimembrane as Mtb phagosome damage response, independent of autophagy.

Happy to share the latest work from the lab @crick.ac.uk. Outstanding work from Di Chen and Tony Fearns showing the link between Mtb membrane damage, calcium leakage and ATG8/LC3 lipidation in macrophages. Congratulations Di and Tony!
www.science.org/doi/10.1126/...

Really cool story. Congrats all ! (although, I would still call this process CASM 😉, multimembrane compartment probably started out as a single membrane one)

Uhh yeah. What is it good for? Absolutely nothing

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Twitter suffered an outage….. and I didn’t even notice.

Spontaneous transformation/emt? Can happen in mcf10a cells if a bit old and left too confluent.

VitA and nutrition for measles, are the thoughts and prayers for mass shootings

War and Peace novel: 560,000 words long
What's it about: war and peace

I feel seen.

Maybe they just turned it off in Cambridge

UK safari not working

American politics is a joke. With a chief joker. Heartbreaking for the world

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I wonder when Trump will start referring to the Ukraine war as "the Russian humanitarian effort"

Honored to be involved with this event. Celebrating Len and Phill, titans of lipid signalling!

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Fantastic story. Well done all!

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Quick, US colleagues. Add something about Ley Lines and nanobots into your NIH grants! Good luck

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Sad. He did some of my favorite screen things.