Michael Hanna

The Hanna lab has a website! 🖥️

Come check it out to see what we’ll be up to 😁

sites.psu.edu/hannalab

Congrats on the fantastic work!

Much needed good news!! Our paper is just out in @jcb.org. We found a crazy antagonistic motor function that explains the elongation/retraction phenotype we see during LRRK2-dependent lysosomal tubulation. I am especially proud of Tsion, Nuria, Mia and Irene's contribution. Check it out!

How delivery of new membrane lipids to lysosomes may limit or even repair damage remains unclear. This is a big emphasis for my future work!

Loss of BLTP3A leads to increased lysosome fragility. Our working hypothesis is that CASM recruits BLTP3A to transfer lipids to damaged lysosomes in participation with other lipid transfer proteins.

We find that BLTP3A, a lipid transfer protein structurally related to VPS13 and ATG2 proteins, plays a role in the response to lysosome damage as an effector of the CASM (conjugation of ATG8 to single membranes) pathway

First, a special shout out to @helyrodriguez.bsky.social – a fantastic scientist who put in a tremendous effort on this manuscript

New paper alert! I’m very excited to share our paper published in @embojournal.org! @pdc-lab.bsky.social @yaleneuro.bsky.social

@anbangdai.bsky.social et al. @pdc-lab.bsky.social report the localization of BLTP2 in different human cell types & reveal binding partners that mediate its tethering to the PM & to PM-connected structures including certain #endosomes & #macropinosomes undergoing fusion rupress.org/jcb/article/...

A headshot of Ben Johnson, on a light blue background with dark blue text reading “Ben Johnson, PhD, De Camilli.” The "Open Science Champion" badge and ASAP logo are also present.

👏 We’re recognizing Ben Johnson (CRN Team De Camilli) as this month’s Open Science Champion!

Ben developed a color-coded Open Science compliance manual that makes ASAP policies easier to navigate and apply. Thank you for raising the bar for #OpenScience, Ben!

Check out the manual: bit.ly/46DuL6R

Faculty opening in Cornell Chemistry at the Assistant Professor level in the area of chemical biology, broadly defined! academicjobsonline.org/ajo/jobs/30338 #chemjobs

Thrilled to share that I’m starting my lab in the Department of Neuroscience at the University of Florida! We’ll study metabolism in brain aging to better understand Alzheimer’s disease. Excited to build, collab, and discover. Go Gators! 🐊
#Neuro #Aging #Alzheimers #UF
ufresearch.bsky.social‬

In a time as this— I am deeply thankful to be blessed with this honor. As a scientist and educator, the NSF CAREER award allows me to integrate the very core of who I am as a scientist and educator.

Forever grateful to past and present members of my lab for helping me accomplish this dream.

One for the Apicomplexa peeps:
ever wonder how does the IMC grow so fast during progeny formation? Where do all the lipids come from? In our latest work on malaria RBC stages we implicate this monster protein (~6000 residues!) and ER contact sites.
Happy+proud to share and keen to hear thoughts!

A bridge-like lipid transfer protein is critical for generation of invasive stages in malaria parasites Malaria blood stages build and maintain an intricate system of membranes during their cycle of rapid growth and schizogony (daughter-cell formation), requiring precise mechanisms of lipid synthesis an...

Beautiful preprint from @aguillensamander.bsky.social who uncovered an essential role for a bridge-like lipid transfer protein (PfVPS13L1) on the growth of the inner membrane complex (IMC) in P. falciparum parasites: www.biorxiv.org/content/10.1...

Congrats, Anup!

Check out this great new preprint by Sam Block et al. from @mvhlab.bsky.social @korylab.bsky.social uncovering how a range of neutral amino acids are transported in mitochondria www.biorxiv.org/content/10.1...

Thank you so much, Tara!

Thank you, Saket!

Thank you, Jeeyun!

Thank you, Mark! I'm very excited to get going

Thank you, Stephen!

Thank you so much, Sam!

Thank you thank you!

Thank you, Krishna!

Thank you, Kamal! I hope you are doing well – we should catch up

Thank you, Sho! We should definitely catch up

Thank you, Natalie!

A very special first post on Bluesky: I’m excited to share that I’ll be starting my lab at Penn State this coming January in the Dept of Biochemistry & Molecular Biology! I’ll be hiring at all levels soon. Check out updates, thoughts, and positions on the lab account: @hanna-lab.bsky.social