Uri Manor

Thrilled to share a new preprint! 📝 🎉 Lewis lab PhD student Casadora wondered: Do mtDNA synthesis and lipid droplet biogenesis co-occur at the same membrane contact sites? Or can we discern distinct ER-mito contact classes? Evidence suggests the latter, relevant in overnutrition!

Omg

I need feedback on my application. Do I know anyone with a Sloan award or, even better, has reviewed such applications in the past?

Associate Editor or Senior Editor, Nature Methods Title: Associate or Senior Editor, Nature Methods Organization: Nature Portfolio Locations: New York, Jersey City, Shanghai or Beijing Closing Date: August 3, 2025    About Springer Nature Springer Na...

Nature Methods is also hiring to replace me (applications close August 4th!!!) and I will do everything I can to support their next bioimaging editor (ask me anything!). springernature.wd3.myworkdayjobs.com/SpringerNatu...

Associate or Senior Editor, Nature Biomedical Engineering Job Title: Associate or Senior Editor, Nature Biomedical Engineering Organization: Nature Portfolio Location: New York, Jersey City, Shanghai or Beijing – Hybrid Working Closing date: August 20, 2025 ...

If you’d like to join me on this journey, NBME is hiring!! This is a fantastically rewarding career that keeps you very much in science. springernature.wd3.myworkdayjobs.com/SpringerNatu...

This is 100% true, although I cannot speak to any times of imperfection - Rita is the ideal editor, and is in my opinion the strongest possible argument for why science as a whole benefits from edited journals (in spite of all the issues).

Congrats, Rita - they're so lucky to have you!!!

a bunch of balloons are flying in the sky . ALT: a bunch of balloons are flying in the sky .

I have some BIG NEWS to share today!

Today I begin my next adventure as

Chief Editor of Nature Biomedical Engineering!!

(a thread) @natmethods.nature.com @natbiomedeng.nature.com @natureportfolio.nature.com

Sharing since I’m seeing lots of posts about this article and I myself was quite distraught when I saw it. Let’s see.

😱😱😱

A major NIH grant to study ways to restore hearing was terminated by the Trump administration bc it was awarded through a DEI initiative—to a researcher who qualified bc of his own hearing loss www.cnn.com/2025/07/29/h... @manorlaboratory.bsky.social

It's gorgeous! That spiral structure of hair cells is almost like a row of piano keys - they each respond to different tones across a gradient and send them to the audio cortex, which has a similar map of tones in the first layer of cortical neurons. Your brain and ear form a piano made of neurons!

really nice cochlea whew!

I think we used Arivis or ZEISS ZEN software for this one

We are working hard on ways to bridge the large FOV lightsheet imaging with our super-resolution imaging of subcellular structures using sample preparation, optical, and computational tricks (e.g. deep learning-based methods).

This imaging method allows us to see the complex tissue context organization of the cochlea without distorting it, which is usually required for higher resolution confocal imaging.

A beautiful tour through an AAV-PHP.B-GFP-transduced intact cochlea as visualized via lightsheet microscopy after tissue clearing. Magenta is a hair cell marker, yellow is a neuron marker, and green is AAV-GFP (relatively low hair cell transduction rate in this specific sample).

Thank you ❤️

Hearing Loss May Be the Canary in the Coal Mine for Dementia Uri Manor’s own hearing loss may not have originally inspired his research path, but his work on the topic now may lead to new treatments and insights on aging.

Very flattering article about my path in science

www.the-scientist.com/hearing-loss...

Interview: How a Hearing-Loss Grant Got Cut in the Fight Over DEI “It felt like the floor dropped out,” researcher Uri Manor said after the sudden suspension of his lab’s award.

How a Hearing-Loss Grant Got Cut in the Fight Over DEI undark.org/2025/07/11/i... via @undark.org

It has been a dream come true to lead a rotation in the @mblscience.bsky.social Physiology course - thanks to the amazing Directors @gladfelterlab.bsky.social and @brangwynnelab.bsky.social, course staff, TAs, and students!

Interview: How a Hearing-Loss Grant Got Cut in the Fight Over DEI “It felt like the floor dropped out,” researcher Uri Manor said after the sudden suspension of his lab’s award.

undark.org/2025/07/11/i...

Crazy full for Uri Manor @manorlaboratory.bsky.social giving the closing plenty #mmc2025

@royalmicrosoc.bsky.social @globalbioimaging.bsky.social @bioimaginguk.bsky.social @eurobioimaging.bsky.social

That worked!!!

That worked!!!

Gifs don’t work on bluesky? :-(

Excited and honored to speak at the @royalmicrosoc.bsky.social meeting tomorrow where I'll talk about our latest AI tools. Meanwhile, check out Vijay&Arlo's Napari "bootstrapper" plugin for massively accelerated segmentation of multidimensional imaging datasets

Github: github.com/ucsdmanorlab...

So great to see you - it's been way too long! Thank you for all your advice/guidance!!!

With @manorlaboratory.bsky.social

Nice to meet @manorlaboratory.bsky.social in Canada and learn of his work on label-free imaging!